DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1561 and CG5126

DIOPT Version :9

Sequence 1:	NP_996412.1	Gene:	CG1561 / 32108	FlyBaseID:	FBgn0030317	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_608584.1	Gene:	CG5126 / 33306	FlyBaseID:	FBgn0031320	Length:	455	Species:	Drosophila melanogaster

Alignment Length:	476	Identity:	104/476 - (21%)
Similarity:	186/476 - (39%)	Gaps:	95/476 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 EQVTQFLRQLVSQLWPELGANPELRLERASAKG----DNYLGVVWRLQ---AASDSKRS--LVVK 281
            :|:....|.||..::...|  |...||..|.:.    |.::..::.:.   ..::.||:  ::||
  Fly     6 QQLDYIERHLVYDIFKNFG--PSASLESHSVECSNGLDGFMSALYTVTLDVVIAERKRTEVVLVK 68

  Fly   282 LPPQNRVRRKQFFARPCFLRETAAYEVFLP----------LTALIQDKWKIIGDDRFRQHALCFG 336
            ........|:...:...|..|..||...||          |.:.:...|.          ..|:.
  Fly    69 FMKGTEEFRESSNSYIQFSNEIFAYAEILPAYENVLRTSHLESEVVKNWV----------PCCYF 123

  Fly   337 TR-------QDEPNECIVLEDLSCAGFSLHNRFLDLSVEHVRRVMLTYAKLHAISLAGKRQLPEK 394
            .|       .:.....:.|:.|...|:.|..| |.|..:.:..::......||:..|.|...|..
  Fly   124 ARFGHVEGLGNGRESVLALKHLKGDGYQLGPR-LTLRRDQLEAMVGLVGPFHALGYATKILQPNV 187

  Fly   395 MQQLQQ-LVD----------IFE--QRRDDHALGVYFENLKESALSALLAPADDAYRVRLEAYFA 446
            ..:|:. :||          ||:  .|........:::..||.    ||..||..:...:|.  .
  Fly   188 HARLRAGVVDMPFVSSSGKGIFDVLYRVAFDRFYEFYDRQKEQ----LLQGADPGFGAAIER--L 246

  Fly   447 RGSYFE---LLLPLV--SGF-NCEP---FAVICHGDCWNNNILYKSTERGELEDVRLIDWQLMRY 502
            |..||:   |||..:  |.| ..:|   ||...|||...||:|:......:::.::.||:|.:|:
  Fly   247 REKYFKQPTLLLERIRTSSFAEDQPDSHFATFLHGDYNRNNVLFHYGAEDKVDAIKAIDFQELRF 311

  Fly   503 ASPVTDLAYFLFTCTSRRFRQRHLENMLEDYYEELGLQLIRL----------GERVEQLFPRPAF 557
            ::...||::|::..|....|:....::|..|:..: ::::.|          .:||:||....:|
  Fly   312 STTAIDLSFFMYMNTPSEGRKEIYADLLRKYHRSM-IEMLELVLRRNRNELTDDRVDQLLQEYSF 375

  Fly   558 DE---QVATKAAVGLLLAMMVLPIVTMQGQDVPDLQAISERIEAGATTDLHGAGFLG-----AGN 614
            :.   .....|..|.::.|..||.:....:|..:|..:.|       ||:||..|..     ||:
  Fly   376 ERFNAHFKRYAFYGPMVCMHFLPWLLGTEKDCAELSRLFE-------TDMHGPAFHQLSLDIAGD 433

  Fly   615 EATFKQRIREVILDCVDFNYI 635
            ||  .|.|.:.:....:..|:
  Fly   434 EA--NQEIFKTVRHAYEHGYM 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1561	NP_996412.1	EcKinase	257..546	CDD:281023	70/346 (20%)
CG5126	NP_608584.1	EcKinase	41..353	CDD:281023	69/329 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010