Protein Alignment pkm and E02C12.9

DIOPT Version :10

• Sequence 1: NP_996412.1
• Gene: pkm / 32108
• FlyBaseID: FBgn0030317
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001343650.1
• Gene: E02C12.9 / 183988
• WormBaseID: WBGene00017094
• Length: 352
• Species: Caenorhabditis elegans
• Alignment Length: 272
• Identity: 59/272 - (21%)
• Similarity: 111/272 - (40%)
• Gaps: 44/272 - (16%)

  Fly   287 RVRRKQFFARPCFLRETAAYEV-----FLPLTALIQDKWKIIG-----DDRFRQHALCFGTRQDE 341
            ::.:|:|..:..|..:..|..:     ::.:.|||...|..:.     ..:|..:.|.....:::
 Worm    22 KMMQKKFETKAKFGEDKNATNISEMKGYMSIIALINADWVDVEKGKNVPSKFAVYGLKKFIDEND 86

  Fly   342 PNECIVLEDLSCAGFSLHNRFLDLSVEHVRRVML-----TYAKL------HAISLAGKRQLPEKM 395
            ....::::.:|.|    |:..:.||:.....:.|     |::.|      :....||.....|:|
 Worm    87 MKGFLIVDFVSNA----HDVGMYLSIPADELIPLVRGISTFSALGEKLSDNEKKFAGGSDFLERM 147

  Fly   396 QQLQQLVDIFEQRRDDHALGVY--FENLKESALSALLAPADDAYRVRLEAYFARGSYFELLLPLV 458
              ..||.:....::  |..|:|  ||..|...:..|: .....|:..|:.|   ....|||
 Worm   148 --FSQLFNSSSLQK--HFQGMYSVFEKEKYYQVDGLI-ETFVVYQKLLKKY---TKISELL---- 200

  Fly   459 SGFNCEPFAVICHGDCWNNNILYKSTERGELEDVRLIDWQLMRYASPVTDLAYFLFTCTSRRFRQ 523
             ||.    :|:.|||.|.:|:::.....|:|:...:||||......|..|.|..:..|.|...|:
 Worm   201 -GFK----SVLNHGDLWQSNMIHSMENNGKLKLEAIIDWQSTVILPPGLDTAELIVGCLSAEDRR 260

  Fly   524 RHLENMLEDYYE 535
            ....::|..|::
 Worm   261 EKGHDLLLLYHK 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pkm	NP_996412.1	PTZ00121	<7..222	CDD:173412
		EcKL	257..546	CDD:397213	59/272 (22%)
E02C12.9	NP_001343650.1	Protein Kinases, catalytic domain	3..343	CDD:473864	59/272 (22%)