DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1561 and T16G1.7

DIOPT Version :9

Sequence 1:	NP_996412.1	Gene:	CG1561 / 32108	FlyBaseID:	FBgn0030317	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_506233.1	Gene:	T16G1.7 / 179774	WormBaseID:	WBGene00011801	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	482	Identity:	100/482 - (20%)
Similarity:	178/482 - (36%)	Gaps:	112/482 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 EAKSKDELAENADREKLAEISASEIQ-LTGNLAAPAEQVDQKEAEPDPHEDTE----DERNGEVN 199
            ||:.|..:.:|.|......:...::| :.|         :|...|....::|:    .:.||.::
Worm     3 EAEKKSTILDNGDGLFQTHVQLDDVQDVIG---------EQMNTEARLGKNTKYTVVGDGNGFMS 58

  Fly   200 REHPDRMESPVEQQEDTAKPDEDLPNEQVTQFLRQLVSQLWPELGANPELRLERASAKGDNYLGV 264
            |        .:..:.:...|||.||.    :|:.::.|.|                    :..|:
Worm    59 R--------VILVEPEWTVPDEHLPE----KFILKITSCL--------------------HVHGL 91

  Fly   265 VWRLQAASDSKRSLVVKLPPQNRVRRKQFF---ARPCFLRETAAYEVFLPLTALIQDKWKIIGDD 326
            |.:::..|..      ..|.:........|   |:....||...|:        |.:||.  .::
Worm    92 VEKMKGKSPG------AFPAEQEAALWAIFENEAQQLHNREVNLYK--------ITEKWN--KNE 140

  Fly   327 RFRQHALCFGTRQDEPNEC-----------IVLEDLSCAG--FSLHNRFLDLSVEHVRRVMLTYA 378
            ......:.|..:.|..|:.           :.:..|.|..  :.||.....|:......:.||..
Worm   141 TMLSPKIYFYKKFDAENKTKGILGMEFVSDVTIRHLYCNAKPYELHPVLRSLATLQAGSLHLTED 205

  Fly   379 KLHAISLAGKRQLPEKMQQLQQLVDIFEQRRDDHALGVYFENLKESALSALLAPADDAYRVRLEA 443
            ::::||....:|:...|...:.:.:|:||.|:     :..|.|.|...:             :||
Worm   206 EINSISGFDFKQMMGAMMNEEGMKNIYEQTRE-----INPERLTEKTNT-------------VEA 252

  Fly   444 YFARGSYFELLLPLVSGFNCEPFAVICHGDCWNNNILYKSTERGELEDVRLIDWQLMRYASPVTD 508
            :......|||...|......|. .|:.|||.|..|||:|....|:....::||:||:...:|..|
Worm   253 FGLEVVNFELSCNLNKYVGIER-DVLVHGDLWAANILWKEENDGKFSVSKVIDYQLIHMGNPAED 316

  Fly   509 LAYFLFTCTSRRFRQRHLENMLEDYYEELGLQLIRLGERVEQLFPRPAFD-EQVATK-----AAV 567
            |.....:..|...||.|.|.:||.:||..   |..||:      .:|.:. ||:...     .:.
Worm   317 LVRVFLSTLSGADRQAHWERLLEQFYEYF---LEALGD------DKPPYSLEQLKESYRCYFVSG 372

  Fly   568 GLLLAMMVLPIVTMQGQDVPDLQAISE 594
            ||::..|..||..::.....|.:::.|
Worm   373 GLVMMPMYGPIAQVKLSYSNDTESVEE 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1561	NP_996412.1	EcKinase	257..546	CDD:281023	68/304 (22%)
T16G1.7	NP_506233.1	DUF1679	10..423	CDD:369592	97/475 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2AMXB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433354at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820