Protein Alignment pkm and LOC11175451

DIOPT Version :10

• Sequence 1: NP_996412.1
• Gene: pkm / 32108
• FlyBaseID: FBgn0030317
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_003435871.2
• Gene: LOC11175451 / 11175451
• VectorBaseID: AGAMI1_004011
• Length: 622
• Species: Anopheles gambiae
• Alignment Length: 646
• Identity: 180/646 - (27%)
• Similarity: 314/646 - (48%)
• Gaps: 68/646 - (10%)

  Fly    30 NSPDSTESYPDVDQKSPKRIDVEEPKEENSNNSE-AVQDLEDNRVK------KEELVAEL--EEP 85
            ::.:|....|.|.:::......|...|::|:..: ||:.:|:.:|.      ::||:|::  ||.
Mosquito     5 HNTESGAEQPVVSERATATTPTEASVEKSSDAVDAAVEIVEEKKVDQQQETVQQELIADVVEEEK 69

  Fly    86 RGAEVEHIEKQLAKEIDSKVIDKQELKGIEELDKKIPQLNQTFGDQLLE----------GDDEPE 140
            ...:.|.::..:.:|..::|::          :||..|..:|..|.|.|          |..|..
Mosquito    70 PEQQQETVQDHVREENVAEVVE----------EKKPEQQQETVQDALPEASVEKVLVDGGMAEET 124

  Fly   141 AKSKDELAENADREKLAEISASEIQLTGNLAAPAEQVDQKEAEPDPHEDTEDERNGEVNRE---- 201
            :.:..::.|....|..:::|..| :...:::|..||::..|     :..|.::.|.|:.:.
Mosquito   125 SAAVQKIVEEPHHEDSSDVSVKE-EAVADVSAVTEQIEAVE-----NNVTSEQANSELEKTALLN 183

  Fly   202 -HPDRMESPVEQQEDTAKP----DEDLPNEQVTQFLRQLVSQLWPELGANP---ELRLERASAKG 258
             ..|..|.||..:|.:..|    |....:.::.|:|...:.|:..|.|...   ::..:..|.||
Mosquito   184 GETDAAEHPVASEESSTAPPAVADAASSSGELPQYLYNAMEQVAIEQGFTAGKFKIEFDVGSNKG 248

  Fly   259 DNYLGVVWR--LQAASDSKRSLVVKLPPQNRVRRKQFFARPCFLRETAAYEVFLPLTALIQDKWK 321
            |.::|.:::  || ..|.:...:.|:||.|..||:||.:...|.|||.||:..|||....|::..
Mosquito   249 DGFVGQMFKAFLQ-EGDRREVYLCKIPPLNEARRQQFQSMTIFSRETLAYKSLLPLIFTYQEEKG 312

  Fly   322 IIGDDRFRQHALCFGTRQDEPNE--CIVLEDLSCAGFSLHNRFLDLSVEHVRRVMLTYAKLHAIS 384
            |..:|.|.....|:....||..|  .|::|||....:.:.|:.:.::.||.|..|....:|||:|
Mosquito   313 ISREDGFFNVPKCYYAECDETTEQSVIIMEDLRLKDYRMWNKLVPVNYEHARLTMQQLGRLHAVS 377

  Fly   385 LAGKRQLPEKMQQLQQLVDIFEQRRDDHALGVYFENLKESALS---ALLAPADDAYRVRLEAYFA 446
            ||.||..|...:|. ::.|..|....:   |..||.:....|:   ..|.|.:...|.:::...
Mosquito   378 LAMKRDRPADFEQF-KVPDPLEVMMPE---GSPFEAMMIKMLTDAKETLEPHETKERTKMQKLI- 437

  Fly   447 RGSYFELLLPLVSGFNCEPFAVICHGDCWNNNIL--YKSTERGELEDVRLIDWQLMRYASPVTDL 509
             .:..:.:.....|...||:||:.|||||.||.:  ||:   |..|.|.|:|||:.||.||||||
Mosquito   438 -DNMRQEMKTCTDGALAEPYAVLGHGDCWVNNFMFHYKN---GAPEHVILLDWQITRYVSPVTDL 498

  Fly   510 AYFLFTCTSRRFRQRHLENMLEDYYEELGLQLIRLGERVEQLFPRPAFDEQVATKAAVGLLLAMM 574
            :||:|.||...||:||.:.|:..||..|...|.:||...:::|||.|...|:......|:|:|:.
Mosquito   499 SYFIFCCTDGEFRRRHYDEMMSIYYNSLEALLEKLGHNPQEVFPRTALMRQLRRFGRFGILMAIF 563

  Fly   575 VLPIVTMQGQDVPDLQAISERIEAGATTDLHGAGFLGAGNEATFKQRIREVILDCVDFNYI 635
            ::|::..:.:|:||:...:|:.......||: |..|.| |:..:::|:...|.|.|.:.|:
Mosquito   564 LVPMLCTRNEDLPDMDEAAEKYRETNEMDLN-AMTLNA-NQRAYRERMSSAIRDMVQYGYL 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pkm	NP_996412.1	PTZ00121	<7..222	CDD:173412	45/219 (21%)
		EcKL	257..546	CDD:397213	104/297 (35%)
LOC11175451	XP_003435871.2	None