Protein Alignment nod and CIN8

DIOPT Version :9

• Sequence 1: NP_001285129.1
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_010853.2
• Gene: CIN8 / 856648
• SGDID: S000000787
• Length: 1000
• Species: Saccharomyces cerevisiae
• Alignment Length: 871
• Identity: 187/871 - (21%)
• Similarity: 313/871 - (35%)
• Gaps: 291/871 - (33%)

  Fly     9 VRIAVREAPYRQFLGRREPS-------VVQFPPWSDGKSLIV------------DQNEFHFDHAF 54
            :.:|||      ..||.|..       ||..|..:..|.:.:            :...:..|..|
Yeast    37 ITVAVR------CRGRNEREISMKSSVVVNVPDITGSKEISINTTGDTGITAQMNAKRYTVDKVF 95

  Fly    55 PATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPP---GEILPEHLGILPRA 116
            ....|||.::..:..||....::|:.||.|.||.|.|||:|:|.....   || |.:..||:||.
Yeast    96 GPGASQDLIFDEVAGPLFQDFIKGYNCTVLVYGMTSTGKTYTMTGDEKLYNGE-LSDAAGIIPRV 159

  Fly   117 LGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLGS-------------------------- 155
            |..:|:.:..:|.:    ..|..||||:|||:..|||.|
Yeast   160 LLKLFDTLELQQND----YVVKCSFIELYNEELKDLLDSNSNGSSNTGFDGQFMKKLRIFDSSTA 220

  Fly   156 --------------------------TPHMPMVAARC---------------------------- 166
                                      ||...::..|.
Yeast   221 NNTTSNSASSSRSNSRNSSPRSLNDLTPKAALLRKRLRTKSLPNTIKQQYQQQQAVNSRNNSSSN 285

  Fly   167 -----------------QRCTCLP--------LHSQADLH--------HILELGTRNRRVRPTNM 198
                             ||.:..|        :.:..:.|        ::|:.|.::|:|..|.|
Yeast   286 SGSTTNNASSNTNTNNGQRSSMAPNDQTNGIYIQNLQEFHITNAMEGLNLLQKGLKHRQVASTKM 350

  Fly   199 NSNSSRSHAIVTIHVKSKTHH------SRMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSIN 257
            |..|||||.|.||.:..| |.      |:||:|||||||.:.|:|......:|..:||..||::.
Yeast   351 NDFSSRSHTIFTITLYKK-HQDELFRISKMNLVDLAGSENINRSGALNQRAKEAGSINQSLLTLG 414

  Fly   258 KVVMSMA--AGHTVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKL 320
            :|:.::.  :||  ||:|:|.||.:||.||...:....:|.|||.:....||.|||.:.:.||.:
Yeast   415 RVINALVDKSGH--IPFRESKLTRLLQDSLGGNTKTALIATISPAKVTSEETCSTLEYASKAKNI 477

  Fly   321 RLNP----------------MQVARQKQSLAARTTHVFRQALCTSTAIKSNAANHNSIVVPKSKY 369
            :..|                |::|:.|..|             .||..|      ..|.:.:..|
Yeast   478 KNKPQLGSFIMKDILVKNITMELAKIKSDL-------------LSTKSK------EGIYMSQDHY 523

  Fly   370 STTKPLSAVLHRTRSEL--------GMTPKAKKRARELLELEETTLELSSIHIQDSSLSLLGFHS 426
               |.|::.|...::|:        .:|.|.....::.|:.:||   :.|.:.|..||.....|.
Yeast   524 ---KNLNSDLESYKNEVQECKREIESLTSKNALLVKDKLKSKET---IQSQNCQIESLKTTIDHL 582

  Fly   427 DSDKDRHLMPPPTGQEPRQASSQNSTLMGIVE------------ETEPKESSKVQQSMVAPTVPT 479
            .:..|:.      .:...:.|..|:.|..:.|            |.:..:..::..:.....:.:
Yeast   583 RAQLDKQ------HKTEIEISDFNNKLQKLTEVMQMALHDYKKRELDLNQKFEMHITKEIKKLKS 641

  Fly   480 TVRCQLFNTTISPISLRASSSQRELSGIQPMEETVVASPQQ-------PCLRRSVRLASSMRSQN 537
            |:..|| ||......|:.::.|..|..|:....|::.:.|:       .|:::.:..:
Yeast   642 TLFLQL-NTMQQESILQETNIQPNLDMIKNEVLTLMRTMQEKAELMYKDCVKKILNES------- 698

  Fly   538 YGAIPKVMNL-----------------RRSTRLAGIREHATSV-------VVKNETDAI--PHLR 576
                ||..|:                 ..:..|:.|.|...::       ..||....:  .|:.
Yeast   699 ----PKFFNVVIEKIDIIRVDFQKFYKNIAENLSDISEENNNMKQYLKNHFFKNNHQELLNRHVD 759

  Fly   577 STVQKKRTRNVKPAPKAWMANNTKCFLDLLNNGNVKQLQEIPGIGPKSAFSLALHRSRLGCFENL 641
            ||.:     |::.....::.|..|...|.|:......:|.:     .:|.|..:.:..     :|
Yeast   760 STYE-----NIEKRTNEFVENFKKVLNDHLDENKKLIMQNL-----TTATSAVIDQEM-----DL 809

  Fly   642 FQVKSLPIWSGNKWER-FCQINCLDT 666
            |:.|.:      |||. |..||..|:
Yeast   810 FEPKRV------KWENSFDLINDCDS 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_001285129.1	KISc	8..325	CDD:214526	117/474 (25%)
		KISc	8..318	CDD:276812	114/451 (25%)
		ComEA	540..648	CDD:224472	22/133 (17%)
CIN8	NP_010853.2	KISc_BimC_Eg5	34..486	CDD:276815	117/462 (25%)
		Smc	<493..>772	CDD:224117	53/326 (16%)
		CCDC158	677..>928	CDD:318193	31/185 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930