Protein Alignment nod and si:dkey-26i13.8

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_009304780.1
• Gene: si:dkey-26i13.8 / 797363
• ZFINID: ZDB-GENE-090312-134
• Length: 991
• Species: Danio rerio
• Alignment Length: 711
• Identity: 169/711 - (23%)
• Similarity: 285/711 - (40%)
• Gaps: 184/711 - (25%)

  Fly     2 EGAKLSAVRIAVREAPYRQFLGRREPSVVQFPPWSDGKSLI----VDQNEFHFDHAFPATISQDE 62
            |||.:.|.:|             ....||...|..|..:::    ..:..:.||.||..|.:|::
Zfish    29 EGATIVAHKI-------------DNQMVVLMDPCEDSDNVLRAHRSREKTYMFDLAFDYTATQED 80

  Fly    63 MYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPEHLGILPRALGDIFERVTA 126
            :|.|....|:|.::.|:..|..|||.||.||:::| |       |....||..|.|.|:|..:
Zfish    81 VYVATTKNLIDGVIAGYNATVFAYGPTGAGKTHTMLG-------LDSEPGIYIRTLNDLFRAI-- 136

  Fly   127 RQENNKDA-IQVYASFIEIYNEKPFDLLG-STPHMPM---------VAARCQRCTCLPLHSQADL 180
             :::.:|. ..||.|:||||||...|||. |:.::.:         :|...:..||    :..::
Zfish   137 -EDSTEDLDCSVYMSYIEIYNEMIRDLLNPSSGYLELREDGKGEIRIAGITEFSTC----NAKEI 196

  Fly   181 HHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSKTHHSRMN---------IVDLAGSEGVRRT 236
            ..:|..|.:.|....|..|..|||||||:.:.||.|:....:|         :|||||:|...:|
Zfish   197 MALLTKGNKQRTQESTAANKTSSRSHAILQVTVKQKSRVKDINEEVRVGKLFMVDLAGTERASQT 261

  Fly   237 GHEGVARQEGVNINLGLLSINKVVMSMA----AGHTVIPYRDSVLTTVLQASLTAQSYLTFLACI 297
            .:.|...:||.:||..||::...:.:::    .|...:.||||.||.:|:.:|...|....:..|
Zfish   262 QNRGKRMKEGAHINRSLLALANCINALSEKGGKGAQFVNYRDSKLTRLLKDALGGNSRTVMITHI 326

  Fly   298 SPHQCDLSETLSTLRFGTSAK----KLRLNPMQV----ARQKQSLAARTTHVFRQAL----CTST 350
            ||...:..|:.:||.:...||    |::.|.|.|    |:..:.:|...:.:.|...    .:..
Zfish   327 SPASSNFEESRNTLVYADKAKNIRTKVKRNLMNVSYHLAQYTRIIADLRSEIERLRAKIDQQSQD 391

  Fly   351 AIKSNAANHNSIVVPKSKYS-------TTKPLSAVLHRTRSELGMTPKAKKRARELLELEETTLE 408
            .:|...|:..:|.....:||       ..:.|||  .|.:.|:         .|.|:|||...:|
Zfish   392 QLKGEKADIRNIQAEVQQYSHGEMALLQEQLLSA--FREQMEI---------RRSLMELENCNME 445

  Fly   409 LSSIHIQDSSLSLLGF----------------------HSDSDKDRHLMPPPTGQEPRQASSQNS 451
            |   || |:|..||..                      |:|.::::..||    :||:..::...
Zfish   446 L---HI-DTSRHLLTISDWERDRARARREKDELSGQKKHTDKEEEQESMP----EEPQYVTAARE 502

  Fly   452 TL----------MGIVEETEPK------ESSKVQQSMVAPTVPTTVR------CQLFNTTISPIS 494
            .:          |.:..|.|.|      :|||:::.:......|..|      |::....:....
Zfish   503 EIGPLLAEQRKTMELKRELEEKLLNMKLKSSKIEELLPKRISNTEQRDILMLLCKVHELELEKTE 567

  Fly   495 LRAS------------------SSQRELSGIQPMEETVVASPQQPCLRRSVRLASSM--RSQNYG 539
            ::::                  ..||.|......::.::...|..|:...::...|:  ...:.|
Zfish   568 IQSAVLCKENVLRTKDFIIQRHEQQRTLCDDIIHQQKMLIEDQGLCVPEGLQELYSLYFGELSDG 632

  Fly   540 AIPKVMNLR---------RSTRLAGIREHATSVVVKNETDAIPHLRSTVQKKRTRNVKPAP 591
            .|.:::||.         |..||                |.|.:|.. ..|....|||.:|
Zfish   633 IIDQILNLHTFTTNNLNARQLRL----------------DVISNLEE-ADKAEQSNVKFSP 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	97/338 (29%)
		ComEA	606..>645	CDD:441164
si:dkey-26i13.8	XP_009304780.1	KISc_KIP3_like	12..349	CDD:276821	102/346 (29%)