Protein Alignment nod and kif18a

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001016245.2
• Gene: kif18a / 548999
• XenbaseID: XB-GENE-990470
• Length: 947
• Species: Xenopus tropicalis
• Alignment Length: 812
• Identity: 174/812 - (21%)
• Similarity: 301/812 - (37%)
• Gaps: 265/812 - (32%)

  Fly     7 SAVRIAVREAPYRQFLGRREPS-----VVQFPPWSDGKSLIVDQN-------------------- 46
            |.||:.||..|..:    :|..     |||.   .|...|:.|..
 Frog    10 SHVRVVVRVRPENE----KEKQGNFSRVVQV---VDNHILVFDPKVEEVGFFHGRSAANRDITKR 67

  Fly    47 -----EFHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEIL 106
                 :|.||..|..:.:|.|:::.....:::.:|.|:.||.||||.||.||:::| :..|||
 Frog    68 KNKDLKFVFDCVFDDSSTQLEVFEQTTKIVLEGVLNGYNCTVLAYGATGAGKTHTM-LGSPGE-- 129

  Fly   107 PEHLGILPRALGDIFERVTARQENNKD--AIQVYASFIEIYNEKPFDLLGSTPHMPMVAARCQRC 169
            |   |::...:.:::.|:    |:.||  ...|..|::|:|.|:..|||.::..: .|....|:.
 Frog   130 P---GVMYLTMMELYNRI----ESVKDEKVCNVAISYLEVYIEQIRDLLSNSGAL-AVREDAQKG 186

  Fly   170 TC---LPLH---SQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSKTHHSRMN----- 223
            ..   |.||   |..::..:|:.|.:||...||:||::||||||:..|:::.:...:.:|
 Frog   187 VVVQGLTLHQPKSAEEILQMLDYGNKNRTQHPTDMNASSSRSHAVFQIYLRQQDKTASINQNVRI 251

  Fly   224 ----IVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMA---AGHTVIPYRDSVLTTVL 281
                ::||||||....|..:|...:||.|||..||::..|:.::|   :....||||:|.||.:|
 Frog   252 AKMCLIDLAGSERASATNAKGERLREGTNINRSLLALGNVINALADPKSKKQHIPYRNSKLTRLL 316

  Fly   282 QASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLR----------------------LNP 324
            :.||........:|.:||......:|.:||::...||.::                      ...
 Frog   317 KDSLGGNCRTIMIAAVSPSSLSYDDTYNTLKYANRAKDIKSAVKSNVVSLDSHISQYVKICEQQK 381

  Fly   325 MQVARQKQSLAA----------------------------RTTHVFR------------------ 343
            .::|..|:.|.|                            |...:.|
 Frog   382 KEIAALKEKLKAYEDQKAIAPGKPKQNVLLPPCQNQAEIKRFQEILRCLFTNREEIRAEYLNLEM 446

  Fly   344 -------------------QALCT-STAIKSN--------AANHNSIVVPKSKYSTTKPL---SA 377
                               |.||: ..|:|::        ...:.::::.|.|....|.|   :.
 Frog   447 RFKENELKTYYQKQCFEQIQMLCSQEKAVKASCKRDHRVEVLKNQNVLLQKKKEDELKRLEENTT 511

  Fly   378 VLHRTRSELGMTPKAKKRAREL---LELEETTLELSSIHIQDSSLS---------------LLGF 424
            .|||..||:.:.....|...||   |:....|||::.:..|...::               |:..
 Frog   512 WLHRLESEMKLLNNDGKMPEELGKDLQCHHLTLEVTDLKTQIKHMTRLVALQERENRYNEKLVNA 576

  Fly   425 HSDSDKDRHLMPPPTGQEPRQASSQNSTLMGIV---------EETEPKESSKVQQSMVAPTV--- 477
            ...|.:.::|:....|.......:....:..:|         ::.|..|::|...|.:|..|
 Frog   577 LLPSLRRQYLLLSQVGLADTCVEADFKKIEQLVQREKAVVWADQAESDEANKCDDSEIAAVVTFP 641

  Fly   478 ----PTTVRC------QLFNTT------ISPISLRASSSQRELSGIQPMEETVVASPQQ-----P 521
                ..|..|      ||..:.      .:|:::....:..:.|..:..:|.|   ||:     |
 Frog   642 HLKYSQTTPCKEEKCAQLIQSAEKMAQKENPLAIVRHFTGAQNSQTEEFKENV---PQKAINVVP 703

  Fly   522 CLRRSVRLASSMRSQNYGAIPKVMNLRRSTRLAGIREHATSVVVKNETDAIPHLRSTVQKKRTRN 586
            ..:|:.|              |:|:...||     ..|..:..:.:|...|.:...|
 Frog   704 PRKRTRR--------------KLMDSPMST-----ESHQQNDSISDELSPIVYTPET-------- 741

  Fly   587 VKPAPKAWMANNTKCFLDLLNNGNVKQLQEIP 618
                     :|||...|        ||:.:||
 Frog   742 ---------SNNTVTLL--------KQVAKIP 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	103/359 (29%)
		ComEA	606..>645	CDD:441164	4/13 (31%)
kif18a	NP_001016245.2	KISc_KIP3_like	20..355	CDD:276821	101/352 (29%)