Protein Alignment nod and Klp61F

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Alignment Length: 740
• Identity: 174/740 - (23%)
• Similarity: 300/740 - (40%)
• Gaps: 172/740 - (23%)

  Fly    47 EFHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEIL----- 106
            :|.||.:|.....|.::|..::.||::::|.|:.||..|||||||||:::|......|:.
  Fly    63 KFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWED 127

  Fly   107 PEHLGILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLG------------STPHM 159
            ...:||:||||..:|:.:...:......|    |::|:|||:..|||.            ||...
  Fly   128 DSDIGIIPRALSHLFDELRMMEVEYTMRI----SYLELYNEELCDLLSTDDTTKIRIFDDSTKKG 188

  Fly   160 PMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAI--VTIHVKSK------ 216
            .::....:.   :|:||:.|::.:||.|...|:...|.||:.|||||.:  :.:|::..
  Fly   189 SVIIQGLEE---IPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGED 250

  Fly   217 -THHSRMNIVDLAGSEGVRRTGHE-GVARQEGVNINLGLLSINKVVMSMAAGHTVIPYRDSVLTT 279
             ....::|:|||||||.|.:.|:| |:..:|.||||..||::.:|:.::......:|||:|.||.
  Fly   251 MLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRESKLTR 315

  Fly   280 VLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNP-------------------- 324
            :||.||..::..:.:|.|||...|:.||||||.:...||.::..|
  Fly   316 LLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEID 380

  Fly   325 -----MQVARQKQS--LAART-----------THVFRQALCTSTAIKSNAANHNSIV--VPKSKY 369
                 :..||.|..  ||..|           .....:.:....|:|....|...|.  |..|..
  Fly   381 KLKRDLMAARDKNGIYLAEETYGEITLKLESQNRELNEKMLLLKALKDELQNKEKIFSEVSMSLV 445

  Fly   370 STTKPLSAV---LHRTRSELGMT----PKAKKRARELLELEETTLELSSIHIQDSSLSLLG---- 423
            ..|:.|...   |..|:..|.:|    .|.|:|.:|..||..:.::...: :...:..:|.
  Fly   446 EKTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKELVASHMKTEQV-LTTQAQEILAAADL 509

  Fly   424 -------FHSDSDKDRHLMPPPTGQEPRQASSQ-------NSTLMG----IVEETEPKESSKVQQ 470
                   .|...::.|.|     .::.|::..|       |..::|    :.::.:.....::.|
  Fly   510 ATDDTHQLHGTIERRREL-----DEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQ 569

  Fly   471 SMVAPTVPTTVRCQLFNTTISPISLRASSSQRELSGIQPMEETVVASPQQPC-----LRRSVRLA 530
            .||             |::.....|..:||:    .|:.::|....|.|...     |...|...
  Fly   570 EMV-------------NSSYVSQRLALNSSK----SIEMLKEMCAQSLQDQTNLHNKLIGEVMKI 617

  Fly   531 SSMRSQNYGAIPKVM------------------------NLRRSTRLAGIREHATSVVVKNETDA 571
            |...||.:  :.|:|                        |.|....|..::|...:::..:....
  Fly   618 SDQHSQAF--VAKLMEQMQQQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSV 680

  Fly   572 IPHLRSTVQKKRTRNVKPAPKAWMANNTKCFL----------DLLNNGNVKQLQEIPGIGPKSAF 626
            ..|.:...:|.........|.|....|.:..|          |.|....:.|:::|..:..|::.
  Fly   681 EEHAKQMHKKLEQLGAMSLPDAEELQNLQEELANERALAQQEDALLESMMMQMEQIKNLRSKNSI 745

  Fly   627 SLALH-----RSRLGCFENLFQVKS 646
            |:::|     .|||.....:..:||
  Fly   746 SMSVHLNKMEESRLTRNHRIDDIKS 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	99/297 (33%)
		ComEA	606..>645	CDD:441164	9/43 (21%)
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	102/308 (33%)
		SMC_prok_B	<408..728	CDD:274008	56/344 (16%)
		SMC_prok_B	<651..>921	CDD:274008	22/120 (18%)
		Microtub_bind	923..>1004	CDD:464048