DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment nod and cana

DIOPT Version :9

Sequence 1:NP_001285129.1 Gene:nod / 32107 FlyBaseID:FBgn0002948 Length:666 Species:Drosophila melanogaster
Sequence 2:NP_001027247.1 Gene:cana / 3771934 FlyBaseID:FBgn0040233 Length:1931 Species:Drosophila melanogaster


Alignment Length:704 Identity:166/704 - (23%)
Similarity:275/704 - (39%) Gaps:168/704 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEGAKLSAVRIAVREAPYRQFLGRREPSVVQFPPWSDGKSL-IVDQN--EFHFDHAFPATISQDE 62
            |.....|::::.::..|.       ||.:.......:|:|: :.|.:  .:.||:.|....|..|
  Fly     1 MSTKNASSIQVCIKVRPC-------EPGLTSLWQVKEGRSIQLADSHAEPYVFDYVFDEGASNQE 58

  Fly    63 MYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILPRALGDIFERVTAR 127
            ::..:...:|...::|...|..|||||.:||:|:|    .|:  .::.|::..|..:||::::: 
  Fly    59 VFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTM----MGD--EQNPGVMVLAAKEIFQQISS- 116

  Fly   128 QENNKDAIQVYASFIEIYNEKPFDLLGSTPH--------MPMVAARCQRCTCLPLHSQADLHHIL 184
             |..:|.: :...:|||||||.:|||.....        ..:|...|:...   :.|:.||...|
  Fly   117 -ETERDFL-LRVGYIEIYNEKIYDLLNKKNQDLKIHESGNGIVNVNCKESI---VTSEDDLLRQL 176

  Fly   185 ELGTRNRRVRPTNMNSNSSRSHAIVTIHVKS-KTHHSR--------MNIVDLAGSEGVRRTGHEG 240
            .:|.:.|.|..||||..|||||||..|.::| |:.||.        :::|||||||.|....|..
  Fly   177 YMGNKERVVGETNMNERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGSEQVDPADHAS 241

  Fly   241 VARQEGVNINLGLLSINKVVMSMAAGHTVIP--YRDSVLTTVLQASLTAQSYLTFLACISPHQCD 303
                       .|:....:|.|::......|  :|||.|..::..||......:.:..|:|  ..
  Fly   242 -----------SLMIFRNLVKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITP--SF 293

  Fly   304 LSETLSTLRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQ-----ALCTSTAIKSNAANHNSIV 363
            :.|:.||:.|||.|||:|..| ||.:    :.:.|| :.||     ::......|....|.:.:|
  Fly   294 VEESSSTISFGTCAKKIRCKP-QVCK----IDSETT-MMRQLDRGISMLKDKLAKKKIKNESQLV 352

  Fly   364 VP----KSKYSTTKPLSAV------LHRTRSELGMTPKAKKRARELLEL---EETTLELSSIHIQ 415
            :.    :.|....|.:|:.      |.:.|....:|....:....:|.|   ||:.|...|    
  Fly   353 LQELEGRIKRDMLKIVSSASLDDYRLQKRRRTWTLTASGSEGDAPVLALPEPEESRLPRPS---- 413

  Fly   416 DSSLSLLGFHSDSDKDRHLMPPPTG-----QEPRQASSQNSTLMGIVEETEPKESSKVQQSMVAP 475
                .|........:.|.:.|...|     :|.|..:....|:.|..::...:.:|::...|::.
  Fly   414 ----KLTNLPKPLFQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVMMSK 474

  Fly   476 TVPTTV-RCQLFNTTISPISL-------------------------------------------R 496
            ....:| .|....|.||.::.                                           :
  Fly   475 KYQESVPNCDAPQTEISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHK 539

  Fly   497 ASSSQRE---LSGIQPMEETVVASPQQPC--LRRSVRLASSMRSQNYGAIP-----------KVM 545
            |.|.|.|   ||.|...:.|:| |.||..  |.|.| |.:|...|.....|           |.:
  Fly   540 AKSKQMEEELLSSISEKDSTIV-SLQQSLEELSRDV-LRNSKEDQMRSMCPELESSCERICNKCL 602

  Fly   546 NLRRSTRLAG-------------IREH--ATSVVVKNETDAIPHLRSTVQKKRT 584
            .|.|...||.             :|..  ||.:.:::......|....|.:|.|
  Fly   603 ELERLLPLASASGLDSVACQFDQLRSEIAATRMKLESMLSTFSHASCEVSQKTT 656

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nodNP_001285129.1 KISc 8..325 CDD:214526 96/338 (28%)
KISc 8..318 CDD:276812 92/331 (28%)
ComEA 540..648 CDD:224472 13/71 (18%)
canaNP_001027247.1 KISc 8..316 CDD:214526 97/340 (29%)
Motor_domain 8..310 CDD:277568 94/333 (28%)
SMC_prok_B <471..1270 CDD:274008 37/188 (20%)
Mplasa_alph_rch 924..1647 CDD:275316
CENP-H 1204..>1266 CDD:283493
CALCOCO1 <1489..1850 CDD:285171
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45437928
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.