Protein Alignment nod and unc-104

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_611155.3
• Gene: unc-104 / 36876
• FlyBaseID: FBgn0267002
• Length: 1739
• Species: Drosophila melanogaster
• Alignment Length: 855
• Identity: 199/855 - (23%)
• Similarity: 321/855 - (37%)
• Gaps: 242/855 - (28%)

  Fly     6 LSAVRIAVREAPYR-QFLGRREPSVVQF-------------PPWSDG-KSLIVDQNEFHFDHAFP 55
            :|:|::|||..|:. :.:.|....:::.             |..||. |....|.:.:..||...
  Fly     1 MSSVKVAVRVRPFNSREIARESKCIIEMAGATTAITNPKVPPNTSDSVKRFNFDYSYWSHDHHDA 65

  Fly    56 ATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILPRALGDI 120
            ...:|..:|:.:...::....:|:.....||||||.||||:|    .|....:..||:|....|:
  Fly    66 DFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTM----MGRQEEQQEGIIPMICKDL 126

  Fly   121 FERVTARQENNKDAIQ--VYASFIEIYNEKPFDLLG-------STPHMPMVAARCQRCTCLPLHS 176
            |.|:   |:...|.::  |..|::|||.|:..|||.       .....|::....:..:.|.:..
  Fly   127 FTRI---QDTETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTD 188

  Fly   177 QADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSKTHH----------SRMNIVDLAGSE 231
            ..|:|.:::.|.:.|.|..||||..||||||:.||....:.|.          |::::|||||||
  Fly   189 YQDIHDLIDEGNKARTVAATNMNETSSRSHAVFTIFFTQRRHDLMTNLTTEKVSKISLVDLAGSE 253

  Fly   232 GVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGHT---------VIPYRDSVLTTVLQASLTA 287
            ....||.:|...:||.|||..|.::.||:.::|...:         .||||||.||.:|:.:|..
  Fly   254 RADSTGAKGTRLKEGANINKSLTTLGKVISALAEVASKKKNTKKADFIPYRDSALTWLLRENLGG 318

  Fly   288 QSYLTFLACISPHQCDLSETLSTLRFG---------------TSAKKLRLNPMQVARQKQSLAAR 337
            .|....:|.|||...:..|||||||:.               .:||.:|....::.:.:..|.|.
  Fly   319 NSKTAMIAAISPADINYDETLSTLRYADRAKQIVCKAVVNEDANAKLIRELKEEIQKLRDLLKAE 383

  Fly   338 TTHVFRQ-ALCTSTAIKSNAANHN----SIVVPKSKYSTTKPLSAVLHRT--------------- 382
            ...|..: .|..||.|||...:.|    :..:...:...::.|.|.|:.|
  Fly   384 GIEVQEEDELTKSTVIKSPTKSRNRNGSTTEMAVDQLQASEKLIAELNETWEEKLKRTEEIRVQR 448

  Fly   383 ---RSELGMTPK---------AKKRARELLELEE---------------------------TTLE 408
               .:|:|:..|         :.|:...|:.|.|                           ..::
  Fly   449 EAVFAEMGVAVKEDGITVGVFSPKKTPHLVNLNEDPNLSECLLYYIKEGLTRLGTHEANVPQDIQ 513

  Fly   409 LSSIHI---------QDSSLSLLGFHSDS---DKDRHLMPP---PTGQ-------------EPRQ 445
            ||..||         ::|:::||. |.|:   ...|.|:.|   .||.             .|.|
  Fly   514 LSGSHILKEHCTFENKNSTVTLLP-HKDAIIYVNGRKLVEPEVLKTGSRVILGKNHVFRFTNPEQ 577

  Fly   446 ASSQNSTLMGIVEETEPKESSKVQQSMVAPTVPTTVRCQLFNTTISPISLRASSSQR-------- 502
            |......:     |||.:..::|:::..........:|:|...  ..|.|:|...:|
  Fly   578 ARELRDKI-----ETENEAENEVEKTDTQQVDWNFAQCELLEK--QGIDLKAEMKKRLDNLEEQY 635

  Fly   503 ---ELSGIQPMEE---TVVASPQQPCLRRSVRLASSMRSQNYGAIPKVMNLRR------------ 549
               :|...|..||   |..|  :...|::.|...|...|......|:..:...
  Fly   636 KREKLQADQQFEEQRKTYEA--RIDALQKQVEEQSMTMSMYSSYSPEDFHQEEDVYTNPMYESCW 698

  Fly   550 STRLAGI--------REH--------------------ATSVVVKNE--------TDAI-----P 573
            :.|.||:        |.|                    |.||.:|.:        ||.:     |
  Fly   699 TAREAGLAAWAFRKWRYHQFTSLRDDLWGNAIFLKEANAISVELKKKVQFQFTLLTDTLYSPLPP 763

  Fly   574 HLRSTVQKKRTRNVKPAPKAWMANNTKCFLDLLNNGNVKQLQEIPGIGPKSAFSLALHRSRLGCF 638
            .|.|||......:...||.   .:.|...:::.:..|          |....:||...|.||...
  Fly   764 ELASTVAPVHQEDEFGAPP---VSKTLVAVEVTDTKN----------GATHHWSLEKLRYRLELM 815

  Fly   639 ENLFQVKSLP 648
            ..::.|:|.|
  Fly   816 RQIYNVESPP 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	107/367 (29%)
		ComEA	606..>645	CDD:441164	7/38 (18%)
unc-104	NP_611155.3	KISc_KIF1A_KIF1B	2..358	CDD:276816	108/362 (30%)
		Kinesin_assoc	355..498	CDD:465047	24/142 (17%)
		FHA_KIF1	474..574	CDD:438757	17/100 (17%)
		YhaN	<575..>666	CDD:443752	21/99 (21%)
		KIF1B	878..924	CDD:463574
		DUF3694	1199..1347	CDD:463599
		PH_KIFIA_KIFIB	1602..1704	CDD:269939