Protein Alignment nod and Khc

DIOPT Version :9

• Sequence 1: NP_001285129.1
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 673
• Identity: 170/673 - (25%)
• Similarity: 275/673 - (40%)
• Gaps: 173/673 - (25%)

  Fly    29 VVQFPPWSDGKSLIVDQNEFHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGK 93
            ||:||...:...:.:....:.||..|....||:::|......:|..:|.|:..|..|||||.:||
  Fly    34 VVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGK 98

  Fly    94 SYSM-GMTPPGEILPEHLGILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLGSTP 157
            :::| |:.  |:.:.:  ||:||.:.|||..:.|.:.|.:..|:|  |:.|||.:|..|||..:.
  Fly    99 THTMEGVI--GDSVKQ--GIIPRIVNDIFNHIYAMEVNLEFHIKV--SYYEIYMDKIRDLLDVSK 157

  Fly   158 ----------HMPMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIH 212
                      .:|.|....:|....|    .|:..::|.|..||.:..||||.:|||||::..|:
  Fly   158 VNLSVHEDKNRVPYVKGATERFVSSP----EDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLIN 218

  Fly   213 VK------SKTHHSRMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGH-TVI 270
            ||      .|....::.:|||||||.|.:||.||....|..|||..|.::..|:.::|.|: |.|
  Fly   219 VKQENLENQKKLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKTHI 283

  Fly   271 PYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSLA 335
            |||||.||.:||.||...:..|.:.|.||...:.|||.|||.||..||.:
  Fly   284 PYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTV--------------- 333

  Fly   336 ARTTHVFRQALCTSTAIKSNAANHNSIVVPKSKYSTTKPLSAVL---------HRTRSELGMTPK 391
                   :..:|.:..:.:...        |.:|...|..:|.|         ...|...|.|.|
  Fly   334 -------KNVVCVNEELTAEEW--------KRRYEKEKEKNARLKGKVEKLEIELARWRAGETVK 383

  Fly   392 AKKR--ARELLELEETTLEL---------SSIHIQDSSLSLLG------------------FHSD 427
            |:::  ..:|:|.....||:         :::..|.::|:.:.                  :...
  Fly   384 AEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLATECERLYQQL 448

  Fly   428 SDKDRHLMPPPTGQEPRQASSQNSTLMGIVE---------ETEPKESSKVQQSMVAPTVPTTVRC 483
            .|||..:     .|:.:.|......:|...|         ||...|.:::||.
  Fly   449 DDKDEEI-----NQQSQYAEQLKEQVMEQEELIANARREYETLQSEMARIQQE------------ 496

  Fly   484 QLFNTTISPISLRASSSQRELSGIQPMEETVVASPQQPCLRRSVRLASSMRSQNYGAIPKVMNLR 548
                        ..|:.:.....:|.:||..|...|     :|..:.:  ::::..|:.:.:..:
  Fly   497 ------------NESAKEEVKEVLQALEELAVNYDQ-----KSQEIDN--KNKDIDALNEELQQK 542

  Fly   549 RSTRLAGIREHATSVVVKNETDAIPHLRSTVQKKRTRNVKPAPKAWMANNTKCFLDLLNN-GNVK 612
            :|.      .:|.|..::...|...|     ||||.              |:...:||.: |.|.
  Fly   543 QSV------FNAASTELQQLKDMSSH-----QKKRI--------------TEMLTNLLRDLGEVG 582

  Fly   613 QLQEIPGIGPKSAFSLALHRSRL 635
            |     .|.|..: |:.|..|.|
  Fly   583 Q-----AIAPGES-SIDLKMSAL 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_001285129.1	KISc	8..325	CDD:214526	112/313 (36%)
		KISc	8..318	CDD:276812	110/306 (36%)
		ComEA	540..648	CDD:224472	22/97 (23%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	112/308 (36%)
		KISc	12..340	CDD:214526	113/337 (34%)
		Apolipoprotein	595..744	CDD:279749	2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437913
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940