Protein Alignment nod and Kif18a

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001421255.1
• Gene: Kif18a / 362186
• RGDID: 1561740
• Length: 886
• Species: Rattus norvegicus
• Alignment Length: 795
• Identity: 165/795 - (20%)
• Similarity: 289/795 - (36%)
• Gaps: 265/795 - (33%)

  Fly    47 EFHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPEHL 110
            :|.||..|..|.:|.|:::....|::...|.|:.||..|||.||:||:::| |.|       ...
  Rat    73 KFVFDAVFDETSTQMEVFEHTTKPILHSFLNGYNCTVFAYGATGSGKTHTMLGST-------AEP 130

  Fly   111 GILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLL-------------------GST 156
            |::...:.|:|:.:...::..:.:..|  |::|:|||:..|||                   |.|
  Rat   131 GVMYLTMLDLFKCMDEVKDEKECSTAV--SYLEVYNEQIRDLLTNSGPLAVREDAQKGVVVQGLT 193

  Fly   157 PHMPMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSK----- 216
            .|.|              .|..::..:|:.|.:||...||:||:.||||||:..|:::.:
  Rat   194 LHQP--------------KSSEEILQLLDNGNKNRTQHPTDMNAASSRSHAVFQIYLRQQDKTAS 244

  Fly   217 ----THHSRMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMA---AGHTVIPYRD 274
                .|.::|:::||||||....:|.:|....||.|||..||::..|:.::|   ..:..||||:
  Rat   245 INQNVHIAKMSLIDLAGSERASISGTKGTRFVEGTNINKSLLALGNVINALADTKRRNQHIPYRN 309

  Fly   275 SVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLR------------------ 321
            |.||.:|:.||........:|.:||......:|.:||::...||.::
  Rat   310 SKLTRLLKDSLGGNCQTIMIAAVSPSSLFYDDTYNTLKYANRAKDIKSSQLKSNVVNLSSHISQY 374

  Fly   322 -----LNPMQVARQKQSLAA-------------------------------------------RT 338
                 :...::...|:.|.|                                           |.
  Rat   375 VKICNMQKAEILMLKEKLKAYEGQKALTDRNDCAKLVHSNVEDKEIERFQEILNCLFQNREGMRQ 439

  Fly   339 THVFRQALCTSTAIKSN-----------------------AANH-------NSIVVPKSKYSTTK 373
            .::..:.|.....:||:                       ..:|       |..|:.|.|....|
  Rat   440 EYLKVEMLLKENELKSSYHQQCHKQIEMMCSEDKLEKATCRRDHRLEKLKSNRCVLEKKKEEMLK 504

  Fly   374 PL---SAVLHRTRSEL------GMTPKAKKRAREL--LELEETTLELSSIH-------------- 413
            ..   :..|||..||:      |..|:...:....  |.|:...|:....|
  Rat   505 QFDENTNWLHRVESEMRLLGQNGDIPEGLNKDLHCHHLHLQNKDLKTQMGHMMTLAALQEQQHGQ 569

  Fly   414 ------------------IQDSSLSLLGFHSDSDKDRHLM--------PPPTGQEPRQASSQNST 452
                              ::::.||...|.||.....||:        ...|.:...|:....::
  Rat   570 TEAVLNALLPVLRKQYWRLKETGLSNAAFDSDFKDIEHLVERKKVVAWADQTAEHSNQSDVPGTS 634

  Fly   453 LMGIVEETEPKESSKVQQSMVAPTV----------------PTTV----------RCQL---FNT 488
            |:....:..|.:|.....||..|::                |..|          |.||   |:.
  Rat   635 LLMTFPQLGPIQSIPCCSSMSDPSILKITPQRRTKRKLIPSPLKVKHTQKSALSERTQLNDSFSK 699

  Fly   489 TISPISLRASSSQRELSGIQPMEETVVASPQQPCLRRSVRLASSMRSQNYGAIPKVMN-LRRSTR 552
            .:.||......|:|.:..:.|           |..|.|...|:.|...:..|:.:..: |.|:..
  Rat   700 ELQPIVYTPEDSRRTVQDLSP-----------PLARASSHSANGMNDNSLKALCRTESPLSRTEC 753

  Fly   553 LAGIREHATSVV------VKNE-TDAIPHLRSTVQK--------KRTRNVKPAPKAWMANNTKC- 601
            ..|:  ::||.:      :||. .:.:|..:||:.:        |.:|:|..:..::||..|..
  Rat   754 KEGL--YSTSAICDGIKSLKNNLPEPLPSSKSTLHRVESSSFPTKDSRSVSTSVPSYMAMTTAAK 816

  Fly   602 ----FLDLLNNGNVK 612
                |:...::.::|
  Rat   817 RKWKFMSSTSDASLK 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	89/302 (29%)
		ComEA	606..>645	CDD:441164	1/7 (14%)
Kif18a	NP_001421255.1	KISc_KIP3_like	11..355	CDD:276821	91/304 (30%)