Protein Alignment nod and neb

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Alignment Length: 578
• Identity: 140/578 - (24%)
• Similarity: 220/578 - (38%)
• Gaps: 151/578 - (26%)

  Fly    11 IAVREAPYR-------------QFLGRREPSVVQFPPWSDGKSLIV-----DQNEFHFDHAFPAT 57
            :|||..|..             |..|......||....:|..:.:.     ||..:..|......
  Fly   123 VAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYSCDPERKNF 187

  Fly    58 ISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYS-MGMT----------PPGEILPEHLG 111
            ..|.::::....||:|...||:.....||||||:||||| ||:.          ||    .:..|
  Fly   188 ACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPP----HDEAG 248

  Fly   112 ILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLG----------STP--------- 157
            |:||...::|.|:.|.:...:..::|..|:.||||||..|||.          |||
  Fly   249 IIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQQQQR 313

  Fly   158 ------HMPMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVK-- 214
                  ..|:........:...:.|.:.|.:.|.:|...|....|.||..|||||:|..|.:.
  Fly   314 PALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIVLNLT 378

  Fly   215 --------------------SKTHHSRMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKV 259
                                .:|..|::::|||||||.:..:|..|...:|||:||..||::.||
  Fly   379 DLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLTLGKV 443

  Fly   260 VMSMAAGH--------------TVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLST 310
            :.::|...              |.:|||:||||.:|:.:|...|....||.|||......|||:|
  Fly   444 IAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADETLAT 508

  Fly   311 LRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQALCTSTAIKSNAANHNSIVVP-KSKYSTTKP 374
            ||:...|:              |:..|              :|.|.:.|:.|:.. :::....|.
  Fly   509 LRYACKAR--------------SIVNR--------------VKVNESPHDKIIRDLRAEVDRLKS 545

  Fly   375 LSAVLHRTRSELGMTPKAKKRARELLELEETTLELSSIHIQDSSLSLLGFHSDSDKDRHLMPPPT 439
            |.....|.|...|.:.....| :.::|......|:.::..|                       .
  Fly   546 LRNEYERQRRLSGNSNNPVPR-KIIIETSVDETEVEALRQQ-----------------------L 586

  Fly   440 GQEPRQASSQNSTLMGIVEETEPKESSKV----QQSMVAPTVPTTVRCQLFNTTISPI 493
            .:..|:.|....:.|..::|.|.:..|::    ::.:.........:..|.|.|..||
  Fly   587 AERERELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTADPI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	113/396 (29%)
		ComEA	606..>645	CDD:441164
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	117/433 (27%)
		SMC_N	514..>615	CDD:481474	22/152 (14%)
		FHA_KIF14	627..741	CDD:438759	5/18 (28%)