Protein Alignment nod and Kif7

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001419074.1
• Gene: Kif7 / 293047
• RGDID: 1310310
• Length: 1341
• Species: Rattus norvegicus
• Alignment Length: 802
• Identity: 189/802 - (23%)
• Similarity: 309/802 - (38%)
• Gaps: 195/802 - (24%)

  Fly     1 MEGAKLSAVRIAVREAPY--RQFLGRREPSVVQFPPWSDGKSLIVDQNEFHFDHAFPATISQDEM 63
            :.||:.:.||:|:|..|.  ::.|...: |.:|..| ..|:..:.....|.|.........|:.:
  Rat     8 LSGAEEAPVRVALRVRPLLPKELLHGHQ-SCLQVEP-ERGRITLGRDRHFGFHVVLGEDAGQEAV 70

  Fly    64 YQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILPRALGDIFERVTARQ 128
            |||.:.||::...|||..|..||||||:||:|:||......:..:..||:|||:.:.|:.:   .
  Rat    71 YQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLHEDEQGIIPRAMAEAFKLI---D 132

  Fly   129 ENNKDAIQVYASFIEIYNEKPFDLL--GSTPHMPMVAA--RCQRCTC----LPLHSQADLHHILE 185
            ||:.....|:.|::|:|.|:..|||  |:......:..  |.....|    :.:....::..:||
  Rat   133 ENDLLDCLVHVSYLELYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEVDVEGLDEVLSLLE 197

  Fly   186 LGTRNRRVRPTNMNSNSSRSHAIVTIHVKSK-----------THH---SRMNIVDLAGSEGVRRT 236
            :|...|....|:.|..|||||.:.|:.::.:           ..|   |:.:.|||||||.|.:|
  Rat   198 MGNAARHTGATHFNRLSSRSHTVFTVTLEQRGRAPTRLPRPGAGHLLVSKFHFVDLAGSERVLKT 262

  Fly   237 GHEGVARQEGVNINLGLLSINKVVMSMA-----AGHTVIPYRDSVLTTVLQASLTAQSYLTFLAC 296
            |..|...:|.:.||..||::..|:.::.     ..|  ||||||.:|.:|:.||...:....:||
  Rat   263 GSTGERLKESIQINSTLLALGNVISALGDPQRRGSH--IPYRDSKITRILKDSLGGNAKTVMIAC 325

  Fly   297 ISPHQCDLSETLSTLRFGTSAKKLRLNPM-----QVARQKQSLAA------------RTTHVFRQ 344
            :||...|..|||:||.:.:.|:.:|....     :..|..:..||            |..|..|:
  Rat   326 VSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERVPEEQAAGARGPPRHRSETRIIHRGRR 390

  Fly   345 ALCTSTAIKSNAANHNSIVVP-------KSKYSTTKPLSAVLHRTRSELGMTPKAKKRARE-LLE 401
            .||....        ::.|.|       :.:..|:...| :|...::|.|:...|.::.|: |..
  Rat   391 VLCPGVG--------SAAVAPGLGTECARCRARTSAAYS-LLRELQAEPGLPGAAARKVRDWLCA 446

  Fly   402 LEETTLELSSIHIQDSSLSLLGFHSDSDKDRHLMPPPTGQEPRQASSQNSTLMGIVEETEPK--- 463
            :|.....|||....||.:      ..:..|.......:|::..:.:.|...|...|...|.:
  Rat   447 VEGERSALSSASGPDSGI------ESAPADDQAAQGTSGRKGDEGAQQLLILQSQVARLEEENRD 505

  Fly   464 ---------ESSKVQQSMV----APTVPTTVRCQLFN---------TTISPISLRASSSQRELSG 506
                     |..|:|...:    ...|...:|.:|..         ..:||.|.........|.|
  Rat   506 FLAALEDAMEQYKLQSDRLREQQEEMVELRLRLELAQPGWGAPGLLQGLSPGSFVPRPHTAPLGG 570

  Fly   507 IQ------------PMEETVVASPQQPCLRRSVRL-----------ASSMRSQNYGAIP-----K 543
            ..            |.||  |:|.||....:..:.           |||..|:......     :
  Rat   571 AHTHMTGTMPRTCLPGEE--VSSEQQVANGKEAKAELLAQVDKLGSASSTTSEEEEEEEEEPPRR 633

  Fly   544 VMNLRRS-----TRLAGIR------EHATSVVVKNETDAIPHLRSTVQKKRTRNVKPAPKA---- 593
            .::|||:     ::.||:|      .....|..:....|||..::....|.....:.||.|
  Rat   634 TLHLRRNGISNWSQRAGVRPGSPPDRKGPEVCPEEPAAAIPAPQAVGGSKAPGQTRQAPAAMASE 698

  Fly   594 W-----------MANNTKCFLDLLN------------------------------NGNV----KQ 613
            |           :|.|.:...:|:.                              .|.:    :|
  Rat   699 WRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAERVRGELCEGQRQ 763

  Fly   614 LQEIPGIGPKSAFSLALHRSRL 635
            |:|:.|..|:.    |..||||
  Rat   764 LRELEGREPQD----ASERSRL 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	104/338 (31%)
		ComEA	606..>645	CDD:441164	11/64 (17%)
Kif7	NP_001419074.1	KISc_KIF4	15..350	CDD:276823	105/341 (31%)
		Smc	<700..>1196	CDD:440809	14/86 (16%)