Protein Alignment nod and klp5

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_595703.1
• Gene: klp5 / 2540361
• PomBaseID: SPBC2F12.13
• Length: 883
• Species: Schizosaccharomyces pombe
• Alignment Length: 726
• Identity: 174/726 - (23%)
• Similarity: 289/726 - (39%)
• Gaps: 200/726 - (27%)

  Fly     4 AKLSAV--RIAVREAPYRQFLGRREPSVVQFPPWSDGKSLIVDQNEFHFDHAFPATISQDEMYQA 66
            |.|||.  |::..:....: |.|:..:...|     |:.|     .:.||..|..|.:|.::|:.
pombe    70 ATLSATNRRLSTSQQSLAR-LSRKSNNSAGF-----GRDL-----RYAFDRVFDETATQQQVYER 123

  Fly    67 LILPLVDKLLEGFQCTALAYGQTGTGKSYSMG--MTPPGEILPEHLGILPRALGDIFERVT-ARQ 128
            ...||:|.:|:||..|..|||.||.||::::.  |..|        |::...|.::|||:. .|.
pombe   124 TARPLLDNILDGFNATIFAYGATGCGKTHTISGTMQDP--------GLIYLTLKELFERMDHLRD 180

  Fly   129 ENNKDAIQVYASFIEIYNEKPFDLLGS-TPHMPMVAARCQRCTCLPLHSQAD------------- 179
            |...|   :..|::|||||...|||.| ||:         :...|.|...||
pombe   181 EKIFD---LRLSYLEIYNETIRDLLVSPTPN---------QAKPLNLREDADRRITVPGLTSLSP 233

  Fly   180 --LHHILEL---GTRNRRVRPTNMNSNSSRSHAI--VTIHVKSKT-----HH--SRMNIVDLAGS 230
              |..|:::   |..||.:.||..|:.||||||:  ||:..|.:|     .|  :.::|:|||||
pombe   234 ESLEEIIDIIMKGNANRTMSPTEANAASSRSHAVLQVTLIQKPRTAGINEDHTLATLSIIDLAGS 298

  Fly   231 EGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGH--TVIPYRDSVLTTVLQASLTAQSYLTF 293
            |....|...|....||.|||..||::...:.::...|  ..:|||||.||.:|:.||........
pombe   299 ERATATKLRGSRLFEGANINKSLLALGNCINALCDPHRRAHVPYRDSKLTRLLKFSLGGNCRTVM 363

  Fly   294 LACISPHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQALCTSTAIKSNAAN 358
            :.|:||......||.:||::...||.::                 |.|.|
pombe   364 IVCVSPSSVHYEETHNTLKYANRAKNIK-----------------TEVLR--------------- 396

  Fly   359 HNSIVVPK--SKYSTTKPLSAVLHRTRSELGMTPKAKKRARELLELEETTLELSSIHIQDSSLSL 421
             |.|.|.:  |:|                          .:.::||.|...||      ::.|:.
pombe   397 -NMISVDRHVSQY--------------------------VKAIVELREQISEL------ENRLAQ 428

  Fly   422 LGFHSDSD-KDRHLMPPPTGQEPRQASSQNSTLMGIVEETEPKESSKVQQSMVAPTVPTTVRCQL 485
            :...|.|: .|:..:......|.:.|.::|...| ..|||.|.::.         |:....:.:.
pombe   429 IDLSSQSNGSDQDAVTQSFAHESKLAEARNLLRM-TFEETLPLQND---------TINKVEKVKH 483

  Fly   486 FNTTISPISLRASSSQRELSGIQPMEETVVASPQQPCLRRSVRLASSMRSQNYGAIPKVMNLRRS 550
            |:.:|..:....|..:|.|.........:|.|..:..|.|...:.:.:.       |:::..:..
pombe   484 FDDSIRVLKYWLSCYERILPNSADERVFLVRSKLESLLTRRAEIIADID-------PELVYQKFQ 541

  Fly   551 TRLAGI-----REHAT--SVVVKNETDAIPHLRSTVQ------KKRTRNVKPAPKAWMANNTKCF 602
            ..::.|     :|.||  :.|:::|.|.   |:|.::      :.:.....|..::.:.::.|.
pombe   542 RSVSHIINTYKQEGATMYADVLQDEVDL---LKSIIENQVLDAQNKVDEFTPVLESLLRSSFKA- 602

  Fly   603 LDLLNNGNVKQLQEI-------PGIGPKSAFSL---------------ALHRSRLGCF------- 638
            ..||..|.:::|..|       .|:|.|...|:               .::|.|:..|
pombe   603 SSLLKEGGMQELFSILEKWLLGIGLGEKPNISVLSESYKLNSTSDDSRTINRDRVHSFPTQPLLN 667

  Fly   639 ---ENLFQVKS 646
               ..:|.|||
pombe   668 NNLPRMFFVKS 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	106/344 (31%)
		ComEA	606..>645	CDD:441164	12/70 (17%)
klp5	NP_595703.1	KISc_KIP3_like	6..390	CDD:276821	111/350 (32%)