| Sequence 1: | NP_001285129.1 | Gene: | nod / 32107 | FlyBaseID: | FBgn0002948 | Length: | 666 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036442.3 | Gene: | KIF4A / 24137 | HGNCID: | 13339 | Length: | 1232 | Species: | Homo sapiens |
| Alignment Length: | 683 | Identity: | 179/683 - (26%) |
|---|---|---|---|
| Similarity: | 296/683 - (43%) | Gaps: | 143/683 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 EGAKLSAVRIAVREAPYRQFLGRREPS-----VVQFPPWSDGKSLIVDQNEFHFDHAFPATISQD 61
Fly 62 EMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMG--MTPPGEILPEHLGILPRALGDIFERV 124
Fly 125 TARQENNKDAIQVYASFIEIYNEKPFDLL----------------------GSTPHMPMVAARCQ 167
Fly 168 RCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHV-------KSKTHHSRMNIV 225
Fly 226 DLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGHT--VIPYRDSVLTTVLQASLTAQ 288
Fly 289 SYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQALCTSTAIK 353
Fly 354 SNAANHNSIVVPKSKYSTTKPLSAVLHRTRSELGMTPKAKKRARELLE--------LEETTLELS 410
Fly 411 SIHIQDSSLSLLGFHSDSDKDRHLMPPPTGQEPRQASSQNSTLMGIVEETEPKESSKV---QQSM 472
Fly 473 VAPTVPTTVRCQ--LFNTTI--------SPISLRAS---SSQRELSGIQPMEETVVASPQQPCLR 524
Fly 525 RSVRLASSMRSQNYGAIPKVMNLRRSTRLAGIREHATSVVVKNETDAIPHLRSTVQKKRTR---N 586
Fly 587 VKPAPKAWMANNTKCFLDLLNNGNVKQLQEIPG 619 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| nod | NP_001285129.1 | KISc | 8..325 | CDD:214526 | 117/354 (33%) |
| KISc | 8..318 | CDD:276812 | 115/347 (33%) | ||
| ComEA | 540..648 | CDD:224472 | 19/83 (23%) | ||
| KIF4A | NP_036442.3 | KISc_KIF4 | 8..337 | CDD:276823 | 117/351 (33%) |
| SMC_prok_B | <375..714 | CDD:274008 | 53/282 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 496..515 | 4/18 (22%) | |||
| Smc | 558..>918 | CDD:224117 | 15/62 (24%) | ||
| Required for the interaction with PRC1. /evidence=ECO:0000269|PubMed:15297875 | 663..1232 | ||||
| Nuclear localization signal. /evidence=ECO:0000269|PubMed:11736643 | 793..798 | ||||
| Globular | 1000..1232 | ||||
| Pre-SET | <1078..1120 | CDD:368254 | |||
| CRD, required for [4Fe-4S] cluster binding and localization to the spindle midzone and midbody during anaphase and telophase. /evidence=ECO:0000269|PubMed:29848660 | 1086..1144 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1122..1142 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0244 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||