Protein Alignment nod and osm-3

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001367796.1
• Gene: osm-3 / 177141
• WormBaseID: WBGene00003884
• Length: 699
• Species: Caenorhabditis elegans
• Alignment Length: 666
• Identity: 174/666 - (26%)
• Similarity: 282/666 - (42%)
• Gaps: 128/666 - (19%)

  Fly     8 AVRIAVREAPYRQFLGRRE------------PSVVQF---PPWSDGKSLIVDQNEFHFDHAFPAT 57
            :||:|||..|:.|    ||            |:|.|.   .|  ||.:     .:|.||.|:...
 Worm     4 SVRVAVRCRPFNQ----REKDLNTTLCVGMTPNVGQVNLNAP--DGAA-----KDFTFDGAYFMD 57

  Fly    58 ISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPEHLGILPRALGDIF 121
            .:.:::|..::.|||:.::||:..|..||||||:||::|| |:    |.:|...|::|||...||
 Worm    58 STGEQIYNDIVFPLVENVIEGYNGTVFAYGQTGSGKTFSMQGI----ETIPAQRGVIPRAFDHIF 118

  Fly   122 ERVTARQENNKDAIQVYASFIEIYNEKPFDLLGS----------TPHMPMVAARCQRCTCLPLHS 176
             ..||..||.|  ..|:.|::|||||:..||||:          .|...:..|......|   |.
 Worm   119 -TATATTENVK--FLVHCSYLEIYNEEVRDLLGADNKQKLEIKEQPDRGVYVAGLSMHVC---HD 177

  Fly   177 QADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSKT-----HHSRMNIVDLAGSEGVRRT 236
            ......::..|..||.|..|.||.:|||||:|.|::|:..|     ...::|:|||||||...:|
 Worm   178 VPACKELMTRGFNNRHVGATLMNKDSSRSHSIFTVYVEGMTETGSIRMGKLNLVDLAGSERQSKT 242

  Fly   237 GHEGVARQEGVNINLGLLSINKVVMSMAAGHTV-IPYRDSVLTTVLQASLTAQSYLTFLACISPH 300
            |..|...:|...|||.|.::..|:.::..|.:. ||||||.||.:||.||...:....:||:||.
 Worm   243 GATGDRLKEATKINLSLSALGNVISALVDGKSKHIPYRDSKLTRLLQDSLGGNTKTIMIACVSPS 307

  Fly   301 QCDLSETLSTLRFGTSAKKLRLNPM-------QVARQKQSLAARTTHVFRQALCTSTAIKSNAAN 358
            ..:..|||||||:...||.::..|.       .:.|:.|...||.     :::....|:...|..
 Worm   308 SDNYDETLSTLRYANRAKNIKNKPTINEDPKDALLREYQEEIARL-----KSMVQPGAVGVGAPA 367

  Fly   359 HNSIVVPKSKYSTTKPLSAVLHRTRSELGMTPKAKKRARELLELEETTLELSSIHIQDSSLSLLG 423
            .::..:.:.:....:.....::..|.|......:|...::.||......|.:     :::|..|.
 Worm   368 QDAFSIEEERKKLREEFEEAMNDLRGEYEREQTSKAELQKDLESLRADYERA-----NANLDNLN 427

  Fly   424 FHSDSDKDRHLMPPPTGQEPRQASSQNSTLMGIVEETEPKESSKVQQSMVAPTVPTTVRCQLFNT 488
            ....:.|.:.|.....|.|....:......|..::|.|.|.........|....|.   .|:::|
 Worm   428 PEEAAKKIQQLQDQFIGGEEAGNTQLKQKRMKQLKEAETKTQKLAAALNVHKDDPL---LQVYST 489

  Fly   489 TISPISLRASSSQRELSGIQPME------------------ETVVASPQQPCLRRSVRLASSMRS 535
            |...:....|..::|:...:..|                  :|:....||      ::|...:..
 Worm   490 TQEKLDAVTSQLEKEVKKSKGYEREIEDLHGEFELDRLDYLDTIRKQDQQ------LKLLMQIMD 548

  Fly   536 QNYGAIPKVMNLRRSTRLAGIREHATSVVVKNETDA---IPHLRSTVQKKRTRNVKPAPKAWMAN 597
            :....|.|..|.....|   |::.|    |.||.::   :|.:                     :
 Worm   549 KIQPIIKKDTNYSNVDR---IKKEA----VWNEDESRWILPEM---------------------S 585

  Fly   598 NTKCFLDLLNNGNVKQ 613
            .::..|.|.|||.:::
 Worm   586 MSRTILPLANNGYMQE 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	122/341 (36%)
		ComEA	606..>645	CDD:441164	3/8 (38%)
osm-3	NP_001367796.1	Motor_domain	3..327	CDD:473979	124/343 (36%)
		SMC_prok_B	<342..559	CDD:274008	36/235 (15%)
		OmpH	384..>470	CDD:461098	16/90 (18%)