Protein Alignment nod and Kif1b

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_038965095.1
• Gene: Kif1b / 117548
• RGDID: 621520
• Length: 1825
• Species: Rattus norvegicus
• Alignment Length: 810
• Identity: 193/810 - (23%)
• Similarity: 314/810 - (38%)
• Gaps: 209/810 - (25%)

  Fly     1 MEGAKLSAVRIAVREAPYRQFLGRREPS-----VVQFPPWSDGKSLIVDQN------EFHFDHAF 54
            |.||   :|::|||..|:..    ||.|     ::|..  .:..|:|..:|      .|.||:::
  Rat     1 MSGA---SVKVAVRVRPFNS----RETSKESKCIIQMQ--GNSTSIINPKNPKEAPKSFSFDYSY 56

  Fly    55 --------PATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLG 111
                    |...||..:|..:...::....||:.....||||||.||||:|    .|:......|
  Rat    57 WSHTSPEDPCFASQSRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTM----MGKQEESQAG 117

  Fly   112 ILPRALGDIFERVTARQEN-NKD-AIQVYASFIEIYNEKPFDLLG-------STPHMPMVAARCQ 167
            |:|:...::||::   .:| |:| :..|..|::|||.|:..|||.       .....|::....:
  Rat   118 IIPQLCEELFEKI---NDNCNEDMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVE 179

  Fly   168 RCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSKTHH----------SRM 222
            ..:.|.:.|..|:..:::.|.:.|.|..||||..||||||:.||....|...          |::
  Rat   180 DLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKQDPETNLSTEKVSKI 244

  Fly   223 NIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGHT------------VIPYRDS 275
            ::|||||||....||.:|...:||.|||..|.::.||:.::|....            .||||||
  Rat   245 SLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVDNCTSKSKKKKKTDFIPYRDS 309

  Fly   276 VLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNPM-------QVARQKQS 333
            |||.:|:.:|...|....:|.:||...:..|||||||:...||:::.|.:       ::.|:.:.
  Rat   310 VLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKE 374

  Fly   334 LAARTTHVFR-QALCTSTAIKSNAANHNSIVVPKSKYSTTKPLSAVLHRTRSELGMTPKAKKRAR 397
            ...|...:.| |.|.....|.....:::.   ...||                  :......:.|
  Rat   375 EVTRLKDLLRAQGLGDIIDIDPLMDDYSG---SGGKY------------------LKDFQNNKHR 418

  Fly   398 ELLELEE------TTLELSSIHIQDSSLSL---LGFHSDSDKDRHLMPPPTGQEPRQASSQNSTL 453
            .||..|.      :|..:.|:....||.||   .|..|.:.....:|..|.|:|..:...::..:
  Rat   419 YLLASENQRPGNFSTASMGSLTSSPSSCSLNSQAGLTSVTSIQERIMSTPGGEEAIERLKESEKI 483

  Fly   454 MGIVEET-EPK----ESSKVQQSMVAPTVPTTVR--------------CQLFNTTISPISL---- 495
            :..:.|| |.|    |:.::::..:...:...:|              ..|.|....|:..
  Rat   484 IAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLL 548

  Fly   496 -----------RASSSQRE---LSGIQPMEETVVASPQQPCLRRS---------VRLASSMRSQN 537
                       :|.:.:|:   |||....||        .|:.||         |.|....||:.
  Rat   549 YYIKDGITRVGQADAERRQDIVLSGAHIKEE--------HCIFRSERNNTGEVIVTLEPCERSET 605

  Fly   538 YGAIPKVMNLRRSTRLAGIREHATSVVVKNETDAIPH---LRSTVQKKRTRNVKPAPKAWMANNT 599
            |      :|.:|......:|.....::.||......|   .|:..:|..:......|..|    |
  Rat   606 Y------VNGKRVAHPVQLRSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDW----T 660

  Fly   600 KCFLDLLNNGNV-------KQLQEIPGI--GPKSAFSLAL------HRSRLGCFENLFQVKSLPI 649
            ....:||....:       |:|||:..:  ..|....|.|      :.|:|...:...:.:||..
  Rat   661 FAQRELLEKQGIDMKQEMEKRLQEMEILYKREKEEADLLLEQQRLDYESKLQALQKQVETRSLAA 725

  Fly   650 -----------------------WSGNKWE 656
                                   |:..||:
  Rat   726 ETTEEEEEEEEVPWTQHEFELAQWAFRKWK 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	112/359 (31%)
		ComEA	606..>645	CDD:441164	10/53 (19%)
Kif1b	XP_038965095.1	KISc_KIF1A_KIF1B	4..361	CDD:276816	116/372 (31%)
		Kinesin_assoc	358..555	CDD:465047	33/217 (15%)
		FHA_KIF1B	530..639	CDD:438779	24/122 (20%)
		GimC	662..>719	CDD:440992	11/56 (20%)
		KIF1B	845..892	CDD:463574
		KIF1B	<956..975	CDD:463574
		DUF3694	1266..1422	CDD:463599
		PH_KIFIA_KIFIB	1710..1808	CDD:269939