Protein Alignment nod and Kif22

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_006507264.1
• Gene: Kif22 / 110033
• MGIID: 109233
• Length: 690
• Species: Mus musculus
• Alignment Length: 714
• Identity: 193/714 - (27%)
• Similarity: 300/714 - (42%)
• Gaps: 161/714 - (22%)

  Fly     6 LSAVRIAVREAPYRQFLGRREPSVVQFPPWSDGKSLIV-------DQNEFHFDHAFPATISQDEM 63
            |:.||:|||..|:..  |..|...:......|..||.|       :..::.||..:....:|.|:
Mouse    36 LARVRVAVRLRPFMD--GETEAKELPCVRAIDSCSLEVANWKKYQETLKYQFDAFYGEKSTQQEV 98

  Fly    64 YQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPEHLGILPRALGDIFERVTAR 127
            |...:.|::..||||...:.||||.||.||:::| |.       ||..|::||||.|:.:  .||
Mouse    99 YVGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGS-------PEQPGVIPRALMDLLQ--LAR 154

  Fly   128 QENNKDA---IQVYASFIEIYNEKPFDLLGSTPHMPMVAARCQ------RCTCLPLHSQADLHHI 183
            :|:.:..   :.|..|::|||.||..|||.......::...|:      ..|..|:.|.:|....
Mouse   155 EESAEGRPWDVSVAMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLTQKPITSFSDFEQH 219

  Fly   184 LELGTRNRRVRPTNMNSNSSRSHAIVTIHVKS-------KTHHSRMNIVDLAGSEGVRRTGHEGV 241
            ....:|||.|..|.:|..||||||::.:.|..       :....::.::||||||..||||::|:
Mouse   220 FLPASRNRAVGATRLNQRSSRSHAVLLVKVDQRERLTPFRQREGKLYLIDLAGSEDNRRTGNQGI 284

  Fly   242 ARQEGVNINLGLLSINKVVMSMAAGHTVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSE 306
            ..:|...||..|..:.|||.::..|...||||||.||.:||.||...::...:|.|:|.:....:
Mouse   285 RLKESGAINTSLFVLGKVVDALNQGLPRIPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYQD 349

  Fly   307 TLSTLRFGTSAKKL--------RLNPMQVARQKQSLAARTTHVFRQALCTSTAIKSNAANHNSIV 363
            |:|.|.|...:|::        .|.|..:|..|.|.        ::.|..|.|.|:......|..
Mouse   350 TISALNFTARSKEVINRPFTNESLQPHALAPVKLSQ--------KELLGPSEAKKAKGPEEESTG 406

  Fly   364 VPKSKYSTTKPLSAVLHRTRSELGMTPKAKKRARELLELEETTLELSSIHIQDSSLSLLGFHSDS 428
            .|:   ||..|.||     ..:|.:..|.......:||      .|.|:.      .|||  |..
Mouse   407 SPE---STAAPASA-----SQKLSLLQKLSNMDPAMLE------NLLSME------RLLG--SQG 449

  Fly   429 DKDRHLMPPPTGQEPRQASSQNSTLMGIVEETEPK-ESSKVQQ-----SMVAPTVPTTVRCQLFN 487
            .:...|:..|        ..:...||..|||...: |..|::|     .::|...|.....:...
Mouse   450 SQGTPLLNTP--------KRERMVLMKTVEEKNLEIERLKMKQKELEAKVLAQEAPDPREKENTP 506

  Fly   488 TTISPISLRASSSQRELSGIQPMEETVVASPQQPCLRRSVRLASSMRSQNYGAIPKVMNLRRSTR 552
            |.:.|        ....||       .||.|    |:::|                ||.|:|..:
Mouse   507 TILQP--------PASYSG-------TVAKP----LKKAV----------------VMPLQRIQK 536

  Fly   553 LAGIREHATSVVVKNETDAIPHLRSTVQKKRTRNVKPAPKA---------W--------MANNTK 600
            .   ||.:..:             ..::|...|.::|:|::         |        :|:..|
Mouse   537 Q---RESSNQI-------------QLLKKGPKRKLEPSPESEAVEKDEDYWEVQISPELLAHGRK 585

  Fly   601 CFLDLLNNGNVKQLQEIPGIGPKSAFSLALHRSRLGCF---ENLFQVKSLPIWSGNKWERFCQI 661
            ..|||||.|:.::|:.:..||.|.|..:...|...|.|   |:|.||:.:   ||.:.|.|.::
Mouse   586 KLLDLLNEGSARELRSLQRIGQKKAQLIVGWRELHGPFSEVEDLEQVEGI---SGKQVESFLKV 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	109/333 (33%)
		ComEA	606..>645	CDD:441164	14/41 (34%)
Kif22	XP_006507264.1	KISc_KID_like	38..361	CDD:276827	109/333 (33%)
		ComEA	591..641	CDD:441164	17/52 (33%)