Protein Alignment nod and kif27

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_031750817.1
• Gene: kif27 / 100497455
• XenbaseID: XB-GENE-6039606
• Length: 1393
• Species: Xenopus tropicalis
• Alignment Length: 777
• Identity: 187/777 - (24%)
• Similarity: 315/777 - (40%)
• Gaps: 205/777 - (26%)

  Fly     9 VRIAVREAPY--RQFLGRREPSVVQFPPWSDGKSLIVDQNE-FHFDHAFPATISQDEMYQALILP 70
            |::|:|..|.  |:.|...:..|...|   :.:.:||.::. |.||..|..:.|||::|::.|.|
 Frog    18 VKVALRVRPLLSREILHNHQVCVRLVP---NTQQVIVGKDRVFTFDFVFGKSSSQDDVYRSSIKP 79

  Fly    71 LVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILPRALGDIFERVTARQENNKDAI 135
            |:..|:||:..|..||||||:||:|::|......:..|..||:|||:.::|:.: |.:.|.:.::
 Frog    80 LLGSLMEGYNATVFAYGQTGSGKTYTIGGGNVASVADEEKGIIPRAIQELFQCI-AERHNVEFSV 143

  Fly   136 QVYASFIEIYNEKPFDLLGSTPHMP-------------MVAAR-CQRCTCLPLHSQADLHHILEL 186
            :|  |:||:|.|:..|||....:|.             :|.|: ||      :.:..::..:|..
 Frog   144 RV--SYIEVYKEELLDLLELETNMKDLHIREDEKGNTVIVGAKECQ------VENADEVMSLLAA 200

  Fly   187 GTRNRRVRPTNMNSNSSRSHAIVTIHV--KSKTH------------HSRMNIVDLAGSEGVRRTG 237
            |:..|....|.||..|||||||.||.:  :|..|            .|:.:.|||||||.|.:||
 Frog   201 GSAARHTGSTQMNERSSRSHAIFTITICQQSSQHGDDAGTNSIQTITSKFHFVDLAGSERVTKTG 265

  Fly   238 HEGVARQEGVNINLGLLSINKVVMSMA-----AGHTVIPYRDSVLTTVLQASLTAQSYLTFLACI 297
            :.|...:|.:.||.|||::..|:.::.     :.|  |||||:.:|.:|:.||...:....:.||
 Frog   266 NTGERFKESIQINSGLLALGNVISALGDPKRKSAH--IPYRDAKITRILKDSLGGNAKTVMITCI 328

  Fly   298 SPHQCDLSETLSTLRFGTSAKKLRLNP-----------------MQVAR-----QKQSLAARTTH 340
            ||...||.|:|::|::...|:.::..|                 ::|.|     |:.|..:||:.
 Frog   329 SPSSSDLDESLNSLKYANRARNIKNKPVVNYNPDWDRMDEMELEIKVLREALQNQQSSRVSRTSQ 393

  Fly   341 V-------------------------FRQALCTSTAIKSNAANHNSIVVPKSKYSTTKPLSAVLH 380
            |                         |.|..||..|........:...:|:|:.:..:....:..
 Frog   394 VSQDWSQGKDKIRSLEEKVAQLQLECFNQRHCTEEAFSLFLDLKDISGLPQSEKNRVQDWLHLAE 458

  Fly   381 RTRSELGMTPKAKKR-----------------------------ARELLELEETTLELSSIH--- 413
            ..||.:....:...|                             ||:.|||:....::.|:.
 Frog   459 GLRSPVAADAEGSSREEPHHVTILQLKRELKKCQDALATDEEVFARKKLELKGLQEQIQSLQQET 523

  Fly   414 ------IQDSSLSLLGFHSDSDKDRHLMPPPTGQEP---RQASSQNSTLMGIVEETEPKESSKVQ 469
                  :|::..:.........:.:.|:.....::|   ||.|.:|..     ||..|:|.|:..
 Frog   524 EEYQKCLQEAEYTKTLQTEKLVEQQLLIDELKSKKPEIYRQFSQENED-----EEELPREISQRP 583

  Fly   470 QSMVAPTVPTTVRCQLFNTT-------ISPISLRAS----SSQRELSGIQPMEETVV-------- 515
            .     |||.:...|..:::       ..|..:|.|    |.:|.::|.:...:.::
 Frog   584 H-----TVPPSTHTQKLSSSSLQAAGQAEPRKVRTSPPSYSLERMVAGFRTRSQMLLELIEEQDE 643

  Fly   516 -----------ASPQQP--------CLRRSVRLASSMRSQNYGAIPKVMNLRRST--------RL 553
                       ..|.:|        ..|||:....:.|..:.||.....|..|..        .|
 Frog   644 VLHEKFSDQSEEEPDEPEKENRKKSPFRRSINRTWTRRQGSAGAETLNSNSDRENDANSNACPAL 708

  Fly   554 AGIREHATSVVVKNETDAIPHLRSTVQKKR--TRNVKPAPKAWMANNTKCFLDLLNNGNVKQ 613
            ..:||.....|.|.:|..: .|....||.|  |.|:|        ...:...:|:..||..|
 Frog   709 ESLRESQVLNVEKLKTSDV-RLADAKQKMRELTINIK--------MKEELIKELIKTGNDAQ 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	113/344 (33%)
		ComEA	606..>645	CDD:441164	3/8 (38%)
kif27	XP_031750817.1	KISc_KIF4	16..352	CDD:276823	114/347 (33%)
		SMC_prok_B	<363..>586	CDD:274008	35/232 (15%)
		SMC_prok_B	<481..900	CDD:274008	55/300 (18%)
		Smc	<707..>1237	CDD:440809	17/64 (27%)