Protein Alignment nod and kif19l

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_031749711.1
• Gene: kif19l / 100494536
• XenbaseID: XB-GENE-29082239
• Length: 901
• Species: Xenopus tropicalis
• Alignment Length: 702
• Identity: 182/702 - (25%)
• Similarity: 298/702 - (42%)
• Gaps: 137/702 - (19%)

  Fly    12 AVREAPYRQFLGRREPSVVQFPPW---SDGKSLIVDQNEFHFDHAFPATISQDEMYQALILPLVD 73
            |.|:..|         :|...||.   |:|.|  |.|.    ||:. ..:..:|:|.:....|::
 Frog     3 AFRQQAY---------NVAPGPPHNKSSEGPS--VQQT----DHSC-LLLQIEEVYVSTTKSLIE 51

  Fly    74 KLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPEHLGILPRALGDIFERVTARQENNKDAIQV 137
            .::.|:..|..|||.|||||:|:| |       |....||..|.|.|:|..:.. ..|:.| ..|
 Frog    52 GVISGYNATVFAYGPTGTGKTYTMLG-------LDSEPGIYIRTLNDLFRAIEV-SSNSLD-YTV 107

  Fly   138 YASFIEIYNEKPFDLLGSTPHMPM---------VAARCQRCTCLPLHSQADLHHILELGTRNRRV 193
            ..|::|||||...|||.....:.:         :|...:..|    .:..::...|..|.:.|..
 Frog   108 SMSYLEIYNEIIRDLLNPAGVLELREDAKGNIQIAGITEFST----SNAEEIMEFLRKGNKQRTQ 168

  Fly   194 RPTNMNSNSSRSHAIVTIHVKSKTHHSRMN---------IVDLAGSEGVRRTGHEGVARQEGVNI 249
            .||..|..||||||::.:.||.|:....:|         :|||||||...:|.|.|...:||.:|
 Frog   169 EPTAANRTSSRSHAVLQVTVKQKSKGKDINEEVCIGKLFMVDLAGSERASQTRHCGKRMKEGAHI 233

  Fly   250 NLGLLSINKVVMSMA---AGHTVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTL 311
            ||.||::...:.:::   ...|.:.:|||.||.:|:.||...|....:|.|||......|:.:||
 Frog   234 NLSLLALGNCINALSEKGGNRTHVNFRDSKLTRLLKDSLGGNSRTVMIAHISPASTSFEESRATL 298

  Fly   312 RFGTSAKKLRLNPMQVARQKQSLAARTTHV--------------------FRQALCTSTAIKSNA 356
            .:...||.::      .|.|::|...:.|:                    .:|......|.::|.
 Frog   299 IYAYRAKNIK------TRVKRNLQNVSYHIAQYTSIISDLRKEIEHLEEKIKQQEREKKAERTNV 357

  Fly   357 ANHNSIVVPKSKYSTTKPLSAVLHRTRSELGMTPKAK-KRARELLELEETTLELSSIHIQDSSLS 420
            :|....|:.|:...:.:.:|.:    |.:|....|.: :..|.||:||.|.:||   || |:|..
 Frog   358 SNIQGGVLGKASSYSREQMSIL----REQLISAFKEQMEMRRSLLQLENTNIEL---HI-DTSRH 414

  Fly   421 LLGFHS-DSDKDRHLMPPPTGQE-PRQASSQNSTLMGIVEETEPKESSKVQQSMVAPTVPTTVRC 483
            |:.... :.|:.||...|  ||: .|..:::|.......||.|.::.|..:...|  ||......
 Frog   415 LITIADWEQDRARHDKKP--GQKIKRDKTAENRLADSTDEENEEEDGSSPEPHEV--TVAREEIS 475

  Fly   484 QLFNTTISPISLRASSSQR---------ELSGIQPMEETVVASPQQPCLRRSVRLASSMRSQNYG 539
            .|....|...||:|...:|         :|..:.|.:  :.:..||..||...|: ..:..:|..
 Frog   476 MLLAEQIKNASLKAELEKRLSNTKLKASQLERLFPKQ--ISSEEQQEVLRLLCRV-HELEVENTE 537

  Fly   540 AIPKVM---NL--RRSTRLAGIREHAT---SVVVKNET---DAIPHLRSTVQK----------KR 583
            ...|.:   ||  ::...:...::|.|   .::.:.:|   |...|:..::::          |.
 Frog   538 LQAKALCKENLLCQKDFVILHYQQHRTLCDEIIQQQQTLIEDYKIHVPESLERLYQVHSLEVEKG 602

  Fly   584 TRNVKPAPKAWMANNTKCFLDLLNNG------NVKQLQEIPGIGPKSAFSLA 629
            |.| :.....::.:||  ..|.|.:|      |:|||::......||..|.|
 Frog   603 TLN-RLQQFQFVISNT--LRDCLVSGESFQHPNIKQLEKAVAESRKSFHSQA 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	100/330 (30%)
		ComEA	606..>645	CDD:441164	10/30 (33%)
kif19l	XP_031749711.1	Motor_domain	<39..307	CDD:473979	89/280 (32%)
		SMC_prok_B	291..>593	CDD:274008	69/322 (21%)