Protein Alignment nod and kif5c

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_002935337.3
• Gene: kif5c / 100493873
• XenbaseID: XB-GENE-977474
• Length: 959
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 179/676 - (26%)
• Similarity: 283/676 - (41%)
• Gaps: 161/676 - (23%)

  Fly    31 QFPPWSDGKSLIV--DQNEFHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGK 93
            :|.|...|:..:|  ....:.||..||:..:|:.:|.|....:|..:|:|:..|..|||||.:||
 Frog    28 KFIPVFKGEDTVVVGPSKPYVFDKVFPSNTTQEHVYSACAKQIVKDVLDGYNGTIFAYGQTSSGK 92

  Fly    94 SYSMGMTPPGEILPEH--LGILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLGST 156
            :::|    .|: |.:|  :||:||...|||:.:.:..||.:..|:|  |:.|||.:|..|||..:
 Frog    93 THTM----EGK-LHDHQMMGIIPRIAHDIFDHIYSMDENLEFHIKV--SYFEIYLDKIRDLLDVS 150

  Fly   157 P----------HMPMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTI 211
            .          .:|.|    :.||...:.|..::..:::.|..||.|..||||.:|||||:|..|
 Frog   151 KTNLAVHEDKNRVPFV----KGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLI 211

  Fly   212 HVK------SKTHHSRMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAG-HTV 269
            ::|      .|....::.:|||||||.|.:||.||....|..|||..|.::..|:.::|.| .|.
 Frog   212 NIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTH 276

  Fly   270 IPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSL 334
            :|||||.:|.:||.||......|.:.|.||...:.:||.|||.||..||.:: |.:.|   ...|
 Frog   277 VPYRDSKMTRILQDSLGGNCRTTIIICCSPSIFNEAETKSTLMFGQRAKTIK-NTVSV---NLEL 337

  Fly   335 AARTTHVFRQALCTSTAIKSNAANHNSIVVPKSKY----STTKPLSAVLHRTRSELGMTPKAKKR 395
            .|...                          |.||    ..||.|..::.....||.     :.|
 Frog   338 TAEEW--------------------------KKKYEKEKDKTKSLKNIIQHLEMELN-----RWR 371

  Fly   396 ARELLELEETTLELSSIHIQDSSLSLLGFHSDSDKDRHLMPP----P------------TGQEPR 444
            ..|.:.::|.|                     |.||:..:.|    |            :.:|.:
 Frog   372 RGEAVPVDEQT---------------------SAKDQKTLEPCDNTPVIDNGLVGATNISSEEKK 415

  Fly   445 QASSQNSTLMGIVEETEPKESSKVQQSMVAPTVPTTVRCQLFNTTISPISLRASSS------QRE 503
            :.....::|.|   :.:.|:....|||.:..        :|....:....|.||:.      |.|
 Frog   416 KYDEDIASLYG---QLDDKDDEINQQSQLIE--------KLKQQMLDQEELLASTRRDYEKIQEE 469

  Fly   504 LSGIQPMEETVVASPQQPCLRRSVRLASSMRSQNYGAIPKV-MNLRRSTRLAGIREHATSVVVKN 567
            |:.:| :|........:..|:....||.:...::.....|. :|.:.|..|.  ::.....|.:.
 Frog   470 LTRLQ-IENDAAKDEVKEVLQALEELAVNYDQKSQEVEDKTKLNEQLSEELT--QKTTNLTVTQR 531

  Fly   568 ETDAIPHLRSTVQKKRTRNVKPAPKAWMANNTKCFLDLL-----------NNGNVKQLQEIPGIG 621
            |...:..| |..|:|||..:               |:||           ...:||.|.|:.|:
 Frog   532 ELSQLQEL-SNHQRKRTTEI---------------LNLLLKDLGEIGGIVGTNDVKTLAEVNGV- 579

  Fly   622 PKSAFSLALHRSRLGCFENLFQVKSL 647
            .:..|::|    ||...:...:||||
 Frog   580 IEEEFTMA----RLYISKMKSEVKSL 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	109/307 (36%)
		ComEA	606..>645	CDD:441164	10/49 (20%)
kif5c	XP_002935337.3	KISc_KHC_KIF5	6..327	CDD:276820	111/309 (36%)
		EnvC	452..>676	CDD:443969	39/174 (22%)
		SMC_prok_B	580..>912	CDD:274008	8/26 (31%)
		Khc_CBD_cc	836..905	CDD:467880