Protein Alignment nod and kif18b

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_002939283.3
• Gene: kif18b / 100490953
• XenbaseID: XB-GENE-5960389
• Length: 872
• Species: Xenopus tropicalis
• Alignment Length: 810
• Identity: 190/810 - (23%)
• Similarity: 305/810 - (37%)
• Gaps: 221/810 - (27%)

  Fly     9 VRIAVREAPYRQFLGRREP-----SVVQFPPWSDGKSLIVDQNE--------------------- 47
            |.:.||..|..|    ||.     :|||.   .|...|:.|.:|
 Frog    13 VSVVVRVRPPNQ----REQEGNHHAVVQV---VDHNMLVFDPDEPETTGVFSSLRGNDGPKRKGK 70

  Fly    48 ---FHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPE 108
               |.||..|.....|.::::.....::|.:|.|:.|:..|||.||.||:::| |    .|..|
 Frog    71 DMKFIFDRIFGENSRQQDVFEHTTKEILDGVLNGYNCSVFAYGATGAGKTHTMLG----SEADP- 130

  Fly   109 HLGILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLL---GS-----TPHMPMVAAR 165
              |::...:.:::.|:.|.:|  :.:.:|..|::|:|||:..|||   ||     .|...:|...
 Frog   131 --GVMYLTMVELYRRIEAIKE--EKSCEVLISYLEVYNEQIQDLLEPRGSLAIREDPQKGVVVQG 191

  Fly   166 CQRCTCLPLHSQADLHHILEL---GTRNRRVRPTNMNSNSSRSHAIVTIHVKSK---------TH 218
                  |..|.......:|::   |..||...||:.|::||.|||:..|:||.:         ..
 Frog   192 ------LSFHQPKSADQLLQMLASGNLNRTQHPTDANASSSHSHAVFQIYVKQQDRTVSISQDVR 250

  Fly   219 HSRMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGHTV---IPYRDSVLTTV 280
            .::|:::||||||....|..:|...:||.|||..||::..|:.::|...:.   ||||||.||.:
 Frog   251 VAKMSLIDLAGSERASTTNAKGERLREGANINRSLLALINVINALADAKSKKAHIPYRDSKLTRL 315

  Fly   281 LQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLN---------------------- 323
            |:.|:........:|.|||......:|.:||::...||:::|:
 Frog   316 LKDSIGGNCRTVMIAAISPSALSYDDTYNTLKYANRAKEIKLSMKSNVINLDCHISKYAAVCEEL 380

  Fly   324 PMQVA--RQK----------------QSLAARTTHVFRQ------------ALCTSTAIKSNAAN 358
            ..:||  |:|                .||..:|:....:            ||..||: ...:.:
 Frog   381 KAEVAELREKLRFYEMKEQPDDDTSDNSLQDKTSPRREEHSDLGSPEQGSGALLLSTS-SCQSQD 444

  Fly   359 HNSIVVPKSKYSTTKPLSAVLHRTRSELGMTP----KAKKRARELLELEETTLELSSIHIQDSSL 419
            |....:...|:... ||:..|  .|.||...|    ..|..|.|.|    .|..|:.:..|...|
 Frog   445 HKPAEMNPRKWDQV-PLNCSL--GREELEKNPCLHEALKDDAAERL----VTSLLNFVRKQCEIL 502

  Fly   420 SLLGFHSDSDKDRHLMPPPTGQEPRQAS-----SQNSTLMGIVEE---TEP------KESSKVQQ 470
            .|.|.::          |....|.||..     .|.:|...:.|:   ||.      ||..:|.|
 Frog   503 KLAGLYT----------PELEDELRQLEGLALRGQKATAEKVTEKEQVTEEHEMETHKEQEEVPQ 557

  Fly   471 SMVAPTVPTTVRCQLFNTTISPISLRASSSQRELSGIQPMEETVVASPQQPCLRRSVRLASSMRS 535
            :.:...|...::.::....:.|...| ...:|..:.|.|.....:.||..|..||.
 Frog   558 TPLVEDVVFDIKEEVIEDPVPPARKR-KPGKRYRADILPDNSPSLRSPIVPVKRRR--------- 612

  Fly   536 QNYGAIPKVMNLRRSTRLAGIREHATSVVVKNETDAIPHLRSTVQKKRTRNVKPAPKAWMANN-- 598
                   :..|.....||||:.......|.:....:||. |..|..:.:.|:.|:....:|:.
 Frog   613 -------EATNTPTKARLAGVPSTPEVQVKRPRKSSIPS-RCRVSLRSSLNLLPSNAKDIASQPP 669

  Fly   599 ----------------TKCFLDLLNNGNVKQLQEIP--GIGPK---SAFSLALHRSRLGCFEN-- 640
                            ||..:. |....::....:|  .:.|:   :.|.|    |..|||.:
 Frog   670 SLCTPKQTAKIQSQTVTKSRMP-LGTSAIQNCASVPAAALAPRDMNTTFDL----SEEGCFVSEM 729

  Fly   641 ----LFQVKSLPIWSGNKWERFCQINCLDT 666
                .|.....|.|..      ..|:.:||
 Frog   730 DKTVTFGTSDFPGWEN------VPIHNIDT 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	103/361 (29%)
		ComEA	606..>645	CDD:441164	10/49 (20%)
kif18b	XP_002939283.3	KISc_KIP3_like	23..355	CDD:276821	101/353 (29%)