Protein Alignment nod and kif19

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_031750317.1
• Gene: kif19 / 100145702
• XenbaseID: XB-GENE-5954822
• Length: 1001
• Species: Xenopus tropicalis
• Alignment Length: 657
• Identity: 156/657 - (23%)
• Similarity: 258/657 - (39%)
• Gaps: 173/657 - (26%)

  Fly     2 EGAKLSAVRIAVREAPYRQFLGRREPSVVQFPPWSDGKSLI----VDQNEFHFDHAFPATISQDE 62
            |||.:.|.::             .|..||...|..|...::    ..:..:.||.||..|.:||.
 Frog    28 EGATIIAHKV-------------DEQMVVLMDPMEDPDDVLRANRSREKSYMFDVAFDYTATQDT 79

  Fly    63 MYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMT--PPGEILPEHLGILPRALGDIFERVT 125
            :|:.....|::.::.|:..|..|||.||.||:|:|..|  .|        ||..|.|.|:|:.:
 Frog    80 VYRLTTKGLIEGVISGYNATVFAYGPTGCGKTYTMLGTDWEP--------GIYIRTLNDLFKAI- 135

  Fly   126 ARQENNKD-AIQVYASFIEIYNEKPFDLLG-STPHMPM---------VAARCQRCTCLPLHSQAD 179
              :|.:.| ..:|..|::|||||...|||. |..::.:         ||...:..|.    :..:
 Frog   136 --EETSDDMEYEVLMSYMEIYNEMIRDLLNPSLGYLDLREDSKGVIQVAGITEVSTI----NAKE 194

  Fly   180 LHHILELGTRNRRVRPTNMNSNSSRSHAI--VTIHVKSKTHH-------SRMNIVDLAGSEGVRR 235
            :..:|..|.:.|...||..|..|||||||  ||:..||:..:       .|:.::||||||...:
 Frog   195 IMQLLMKGNKQRTQEPTAANKTSSRSHAILQVTVRQKSRVKNITQEVRVGRLFMIDLAGSERASQ 259

  Fly   236 TGHEGVARQEGVNINLGLLSINKVV--MSMAAGHTVIPYRDSVLTTVLQASLTAQSYLTFLACIS 298
            |.:.|...:||.:||..||::...:  :|...|:..:.||||.||.:|:.||...|....:|.||
 Frog   260 TQNRGQRMKEGAHINRSLLALGNCINALSERGGNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHIS 324

  Fly   299 PHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQALCTSTAIKSNAANHNSIV 363
            |......|:.:||.:...||.::      .|.|::|...:.|:               |.:.||:
 Frog   325 PASTSFEESRNTLTYADRAKNIK------TRVKRNLLNVSYHI---------------AQYTSII 368

  Fly   364 VPKSKYSTTKPLSAVLHRTRSELGMTPKAKKRARELLELEETTLELSSIHIQDSSLSLLGFHSDS 428
                                |:|         .:|:..|:|        .|.:..|
 Frog   369 --------------------SDL---------RKEIQRLKE--------KIDEQGL--------- 387

  Fly   429 DKDRHLMPPPTGQEPRQASSQNSTLMGIVEETEPKESSKVQQSMVAPTVPTTVRCQLFNTTISPI 493
                           :|..|:.|.:..|..|.:...|...:..|      ..::.||.......:
 Frog   388 ---------------KQLRSEKSDIRNIQAEVQLHSSPYGRHEM------EQLKEQLIRAFREQM 431

  Fly   494 SLRASSSQRELSGIQPMEET-----VVASPQQPCLRRSVRLASSMRSQNYG-------------- 539
            .:|....:.|.|.::...||     ::|..:|...||:.:....:|.:.||
 Frog   432 DIRRQLMEIENSSMEMQMETSRHFLIIADWEQEKARRARKWKDELRKETYGKDDSEKDSDTGDEQ 496

  Fly   540 ----AIPKVMNLRRSTRLAGIREHATSVVVKNETDAIPHLRSTVQKKRTRNVKPA-PKAWMANNT 599
                ..|:|...|.:.:   |.|...|.:.:.:.:.....|..  ::|.|.::.| ||...:.:.
 Frog   497 SDIIEPPEVTTARETIQ---ILEGDQSKLRRQKLELEKRFRDI--RQRARRLEEALPKRISSEDQ 556

  Fly   600 KCFLDLL 606
            :..|.||
 Frog   557 REILSLL 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	101/337 (30%)
		ComEA	606..>645	CDD:441164	1/1 (100%)
kif19	XP_031750317.1	KISc_KIP3_like	11..346	CDD:276821	106/345 (31%)
		SMC_N	<361..>615	CDD:481474	46/290 (16%)