Protein Alignment nod and kif3b

DIOPT Version :10

• Sequence 1: NP_511125.2
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001093615.1
• Gene: kif3b / 100101641
• ZFINID: ZDB-GENE-050119-3
• Length: 775
• Species: Danio rerio
• Alignment Length: 663
• Identity: 171/663 - (25%)
• Similarity: 283/663 - (42%)
• Gaps: 103/663 - (15%)

  Fly    48 FHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSM-GMTPPGEILPEHLG 111
            |.||..:.....|.|:|.....||||.:|.||..|..|||||||||:|:| |:...    ||..|
Zfish    58 FTFDSVYDWNSKQMELYDETFRPLVDSVLFGFNGTIFAYGQTGTGKTYTMEGVRND----PERRG 118

  Fly   112 ILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLG-------STPHMPMVAARCQRC 169
            ::|.:...||..::..|  |:..: |.||::|||.|:..|||.       .....|......:..
Zfish   119 VIPNSFEHIFTHISCSQ--NQQYL-VRASYLEIYQEEIRDLLSKDQARRLELKERPDTGVYVKDL 180

  Fly   170 TCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSK------THHSR---MNIV 225
            :.....|..::.|::.:|.:||.|..||||.:|||||||..|.::..      .:|.|   :|:|
Zfish   181 SSFVTKSVREIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSELGPDGENHIRVGKLNLV 245

  Fly   226 DLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGH-TVIPYRDSVLTTVLQASLTAQS 289
            ||||||...:||.:|...:|...|||.|.::..|:.::..|. |.||||||.||.:||.||...:
Zfish   246 DLAGSERQTKTGAQGERLKEATKINLSLSALGNVISALVDGRSTHIPYRDSKLTRLLQDSLGGNA 310

  Fly   290 YLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNPM---------------QVARQKQSLAARTT 339
            ....:|.|.|...::.|||:|||:...||.::..|.               ::||.|:.|..|:.
Zfish   311 RTVMVANIGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKEQLEKRSG 375

  Fly   340 HVFRQALCTSTAI--------KSNAANHNSIVVPKSKYSTTKPLSAVLHRTRSELGMTPKA---- 392
            ...|:........        :....:.:.....:......|.::...|..:.:|....:|
Zfish   376 RKRRRRRRRRVGEGGEEFEDGEDEEDDDDDDEDEEEGVDADKNIADYWHEQQEKLEKERRAIMED 440

  Fly   393 ------------KKRARELLEL----EETTLELSSIHIQDSSL-----SLLGFHSDSDKDRHLMP 436
                        |::.|::.:|    |.:.:..:.:...:|.|     :::...::..|...|..
Zfish   441 HSLVAEEKQRLLKEKERKMTDLHKEKEASEMLTAKVKAMESKLLVGGKNIVDHTNEQQKVLELKR 505

  Fly   437 PPTGQEPRQASSQNSTLMGIVEET-EPKES-SKVQQSMVAPTVPTTVRCQLFNTTISPISLRASS 499
            ....::.|:.......:....||| |.||: |.:||.:   .:.|....:||:...|..|....:
Zfish   506 QEIAEQKRREREMKQEMECRDEETLELKETYSSLQQEV---DIKTKKLKKLFSKLQSVKSEIQDA 567

  Fly   500 SQRELSGIQPMEETVVASPQQPCLRRSVRLASSMRSQNYGAIP-----KVM---------NLRRS 550
            ....:...|.:|:|      |..|.|.::| ..:..:|:  ||     |::         :|.:.
Zfish   568 QDEHVKYRQELEQT------QNELTRELKL-KHLIIENF--IPMEEKNKIVTRATFDEEDDLWKM 623

  Fly   551 TRLAGIREHATSVVVKNETDAIPHLRSTVQKKRTRNVKPAPKAWMANNTKCFLDLLNNGNVKQLQ 615
            |.:..| :::...::|....|:.:.|...|..|...:......:.|.|. ..|:|.......:..
Zfish   624 TPITRI-QNSDHQMMKRPVSAVGYRRPLSQHARMAMLMRPDVRYKAENI-LLLELDLPSRTTKDY 686

  Fly   616 EIPGIGPKSAFSL 628
            |.|.|.||.|.:|
Zfish   687 EGPVIAPKVAAAL 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_511125.2	KISc	8..318	CDD:276812	105/287 (37%)
		ComEA	606..>645	CDD:441164	7/23 (30%)
kif3b	NP_001093615.1	KISc_KIF3	15..341	CDD:276822	107/289 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	372..419		3/46 (7%)
		Mplasa_alph_rch	<425..>611	CDD:275316	36/197 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	716..775