Protein Alignment nod and kif5b

DIOPT Version :9

• Sequence 1: NP_001285129.1
• Gene: nod / 32107
• FlyBaseID: FBgn0002948
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001122126.1
• Gene: kif5b / 100038146
• XenbaseID: XB-GENE-854737
• Length: 962
• Species: Xenopus tropicalis
• Alignment Length: 720
• Identity: 178/720 - (24%)
• Similarity: 295/720 - (40%)
• Gaps: 190/720 - (26%)

  Fly    31 QFPPWSDGK---------------SLIVDQNEFHFDHAFPATISQDEMYQALILPLVDKLLEGFQ 80
            :|.|.:|.:               ::::....:.||..|.:..||:::|.|....:|..:|:|:.
 Frog    14 RFRPLNDSEVTRGDKYVAKFQGEDTVVMASKPYVFDRVFQSNTSQEQVYNACAKAIVKDVLDGYN 78

  Fly    81 CTALAYGQTGTGKSYSMGMTPPGEIL-PEHLGILPRALGDIFERVTARQENNKDAIQVYASFIEI 144
            .|..|||||.:||:::|    .|::. |:.:||:||.:.|||..:.:..||.:..|:|  |:.||
 Frog    79 GTIFAYGQTSSGKTHTM----EGKLHDPDGMGIIPRIVQDIFNYIYSMDENLEFHIKV--SYFEI 137

  Fly   145 YNEKPFDLLGSTP----------HMPMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMN 199
            |.:|..|||..:.          .:|.|....:|..|.|    .::...::.|..||.|..||||
 Frog   138 YLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSP----DEVMDTIDEGKSNRHVAVTNMN 198

  Fly   200 SNSSRSHAIVTIHVKSKTHHS------RMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINK 258
            .:|||||:|..|:||.:...:      ::.:|||||||.|.:||.||....|..|||..|.|:..
 Frog   199 EHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSSLGN 263

  Fly   259 VVMSMAAGHTVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLR-- 321
            |:.::|.|...||||||.:|.:||.||......|.:.|.||...:.:|:.|||.||..||.::
 Frog   264 VISALAEGSVYIPYRDSKMTRILQDSLGGNCRTTIVICCSPSAYNEAESKSTLLFGQRAKTIKNT 328

  Fly   322 ------------------------------------LN--------PMQVARQKQ---------- 332
                                                ||        |::....|:
 Frog   329 VCVNVELTAEQWKKKYEKEKEKTKSLRSTVQWLENELNRWRKGETVPIEEQYDKEKANMDAFVVD 393

  Fly   333 ----------SLAARTTHVFRQALCTSTAI--------KSNAANHNSIVVPKSKY---------- 369
                      :|||..|...|:. |.....        |....|..|.:|.|.|.
 Frog   394 NFVNNEKPAVTLAANFTDAERRK-CEEEVTKLYKQLDDKDEEINQQSQLVEKLKQQMLDQEELLA 457

  Fly   370 STTKP---LSAVLHRTRSELGMTPKAKKRARELLE-LEETTL----------------ELSSIHI 414
            ||.:.   :.|.|:|.::|   ...:|:..:|:|: |||..:                ::.|..:
 Frog   458 STRRDQDNMQAELNRLQAE---NDASKEEVKEVLQALEELAVNYDQKSQEVEDKSKEYDILSEEL 519

  Fly   415 QDSSLSLLGFHSDSDKDRHLMPPPTGQEPRQASSQNSTLM------GIV----EETEPKESSKVQ 469
            ...|:.|....|:..|.:.:    |..:.::|:...::|:      ||.    :..:|:.|..:.
 Frog   520 NQKSVILSSIDSELQKLKEM----TNHQKKRATEMMTSLLKDLAEIGIAVGGNDGKQPEVSGMID 580

  Fly   470 Q---------SMVAPTVPTTV-RCQLFNTTISPISLRASSSQRELSGIQ---PMEETVVASPQ-- 519
            :         |.:...|.|.| ||:....|.|..:.:...:::||:..|   ...|..:.|..
 Frog   581 EEFTVARLYISKMKSEVKTMVKRCKQLEGTQSESNKKMEENEKELAACQLRISQHEAKIKSLTEY 645

  Fly   520 -QPCLRRSVRLASSMRSQNYGAIPKVMNLRRSTRLAGI-REHATSVVVKNET-----DAIPHLRS 577
             |...::...|..|:.|.|    .:::.||...::..: :||...|....|.     :.|...|.
 Frog   646 VQNVEQKKRHLEESVDSLN----EELVKLRAQEKVHEMEKEHLNKVQTATEVKHAVEEQIQSHRE 706

  Fly   578 TVQKK 582
            |.||:
 Frog   707 THQKQ 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nod	NP_001285129.1	KISc	8..325	CDD:214526	111/371 (30%)
		KISc	8..318	CDD:276812	107/318 (34%)
		ComEA	540..648	CDD:224472	11/49 (22%)
kif5b	NP_001122126.1	KISc_KHC_KIF5	6..325	CDD:276820	109/320 (34%)
		Smc	<409..792	CDD:224117	62/315 (20%)
		COG4372	709..>914	CDD:226809	2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910