Protein Alignment CG11695 and ZNF160

DIOPT Version :10

• Sequence 1: NP_572732.1
• Gene: CG11695 / 32106
• FlyBaseID: FBgn0030316
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_047295573.1
• Gene: ZNF160 / 90338
• HGNCID: 12948
• Length: 837
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 89/319 - (27%)
• Similarity: 137/319 - (42%)
• Gaps: 35/319 - (10%)

  Fly   192 RSSNSREMDSYIALHG---RLECCICGGDEQFPNFAEMKRHFRNH---HQSLGYVVC--CQRRYK 248
            |||    :.::.|:|.   ..:|..||     .:|.: |.|.|:|   |.......|  |.:.:.
Human   540 RSS----LTTHQAIHSGEKPYKCIECG-----KSFTQ-KSHLRSHRGIHSGEKPYKCNECGKVFA 594

  Fly   249 KRALYVDHLHMHNDPNYFRCKICSKQLVSRISYDVHMLRFHP--NKDDLSFACDQCSKRFSKQFL 311
            :.:....|..:|.....::|..|.:....|.|     |.||.  :..:..:.|.:|.|.|.....
Human   595 QTSQLARHWRVHTGEKPYKCNDCGRAFSDRSS-----LTFHQAIHTGEKPYKCHECGKVFRHNSY 654

  Fly   312 LTIHSRVHQQERNEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFICDSCGAKFKTKQNLLVHKRT 376
            |..|.|:|..|:..:|..|.::|....:|..|  :.......|:.|:.||..|....:|..|:||
Human   655 LATHRRIHTGEKPYKCNECGKAFSMHSNLTTH--KVIHTGEKPYKCNQCGKVFTQNSHLANHQRT 717

  Fly   377 VHREGSQLPEVQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHH 441
            ...|    ...:|.||....|..:||..|..:|   ...:.:||.:||......|.||.|.|.|.
Human   718 HTGE----KPYRCNECGKAFSVRSSLTTHQAIH---TGKKPYKCNECGKVFTQNAHLANHRRIHT 775

  Fly   442 PKEYHKCTHCAKEFKSSRSLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQ 500
            .::.::||.|.|.|:...||..|.|.|||:..|:|..|.:.|:.|.|:..|.| ||..:
Human   776 GEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSNLASHHR-MHTGE 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:462262
		C2H2 Zn finger	268..289	CDD:275368	5/20 (25%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		SUF4-like	327..>387	CDD:411020	15/59 (25%)
		C2H2 Zn finger	327..348	CDD:411020	5/20 (25%)
		C2H2 Zn finger	327..348	CDD:275368	5/20 (25%)
		C2H2 Zn finger	357..378	CDD:411020	8/20 (40%)
		C2H2 Zn finger	357..376	CDD:275368	6/18 (33%)
		C2H2 Zn finger	389..409	CDD:275368	7/19 (37%)
		C2H2 Zn finger	420..440	CDD:275368	8/19 (42%)
		C2H2 Zn finger	448..468	CDD:275368	9/19 (47%)
		C2H2 Zn finger	476..494	CDD:275368	6/17 (35%)
ZNF160	XP_047295573.1	KRAB	27..87	CDD:214630
		SFP1	<235..351	CDD:227516
		C2H2 Zn finger	278..298	CDD:275368
		zf-H2C2_2	290..314	CDD:463886
		C2H2 Zn finger	306..326	CDD:275368
		C2H2 Zn finger	334..354	CDD:275368
		zf-H2C2_2	346..369	CDD:463886
		C2H2 Zn finger	362..382	CDD:275368
		COG5048	386..829	CDD:227381	87/313 (28%)
		C2H2 Zn finger	390..410	CDD:275368
		C2H2 Zn finger	418..438	CDD:275368
		C2H2 Zn finger	446..466	CDD:275368
		C2H2 Zn finger	474..494	CDD:275368
		C2H2 Zn finger	502..522	CDD:275368
		C2H2 Zn finger	530..550	CDD:275368	4/13 (31%)
		C2H2 Zn finger	558..578	CDD:275368	8/25 (32%)
		C2H2 Zn finger	586..606	CDD:275368	3/19 (16%)
		C2H2 Zn finger	614..634	CDD:275368	7/24 (29%)
		C2H2 Zn finger	642..662	CDD:275368	7/19 (37%)
		C2H2 Zn finger	670..690	CDD:275368	5/21 (24%)
		C2H2 Zn finger	698..718	CDD:275368	7/19 (37%)
		C2H2 Zn finger	726..746	CDD:275368	7/19 (37%)
		C2H2 Zn finger	754..774	CDD:275368	8/19 (42%)
		C2H2 Zn finger	782..802	CDD:275368	9/19 (47%)
		C2H2 Zn finger	810..830	CDD:275368	7/20 (35%)