Protein Alignment CG11695 and ZNF212

DIOPT Version :10

• Sequence 1: NP_572732.1
• Gene: CG11695 / 32106
• FlyBaseID: FBgn0030316
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_036388.2
• Gene: ZNF212 / 7988
• HGNCID: 13004
• Length: 495
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 56/249 - (22%)
• Similarity: 86/249 - (34%)
• Gaps: 73/249 - (29%)

  Fly   314 IHSRVHQQERNEQCK--------HCDRSFRTAVDLRLHMRRTHDPAFVPFICDSCGAKFKTKQNL 370
            :.|||....|...|.        ..|:.....:.|:....|       |:.|..|...|:.||.|
Human   274 VGSRVPSSSRTVGCPKQKSHRQVQLDQECGQGLKLKKDTSR-------PYECSECEITFRYKQQL 331

  Fly   371 LVHKRTVHREGSQLPEVQCQECQVWLSDENSLR---------KHMYMHLDAASLRQWKC------ 420
            ..|.|:....||..||          ..|.|||         |...:|.....||.:.|
Human   332 ATHLRSHSGWGSCTPE----------EPEESLRPRPRLKPQTKKAKLHQCDVCLRSFSCKVSLVT 386

  Fly   421 -EQCGLEKG--------------SRAKLAAHIRYHHPKEYHKCTHCAKEFKSSRSLEEHTATHTG 470
             ::|.|::|              |...|..||.:...:....|.:|.|.|.....|..|...|||
Human   387 HQRCHLQEGPSAGQHVQERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTG 451

  Fly   471 QDLYECAFCERTFKNSGNMHKHRRQMHAAQVAALQQQKKVPPSKRKDKGDLLLD 524
            :..|.|..||::|....::.:|:: :|                 ::::|.|.|:
Human   452 ERPYSCTECEKSFVQKQHLLQHQK-IH-----------------QRERGGLALE 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:462262
		C2H2 Zn finger	268..289	CDD:275368
		C2H2 Zn finger	299..319	CDD:275368	2/4 (50%)
		SUF4-like	327..>387	CDD:411020	16/67 (24%)
		C2H2 Zn finger	327..348	CDD:411020	4/28 (14%)
		C2H2 Zn finger	327..348	CDD:275368	4/28 (14%)
		C2H2 Zn finger	357..378	CDD:411020	8/20 (40%)
		C2H2 Zn finger	357..376	CDD:275368	7/18 (39%)
		C2H2 Zn finger	389..409	CDD:275368	5/28 (18%)
		C2H2 Zn finger	420..440	CDD:275368	8/40 (20%)
		C2H2 Zn finger	448..468	CDD:275368	6/19 (32%)
		C2H2 Zn finger	476..494	CDD:275368	5/17 (29%)
ZNF212	NP_036388.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		KRAB_A-box	142..180	CDD:143639
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..290		5/15 (33%)
		zf-C2H2	316..338	CDD:395048	8/21 (38%)
		C2H2 Zn finger	318..338	CDD:275370	8/19 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	337..361		8/33 (24%)
		C2H2 Zn finger	371..391	CDD:275368	3/19 (16%)
		C2H2 Zn finger	429..449	CDD:275368	6/19 (32%)
		zf-C2H2	429..449	CDD:395048	6/19 (32%)
		zf-C2H2	455..477	CDD:395048	6/22 (27%)
		C2H2 Zn finger	457..477	CDD:275368	5/20 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..495		4/29 (14%)