Protein Alignment CG11695 and ZFY

DIOPT Version :10

• Sequence 1: NP_572732.1
• Gene: CG11695 / 32106
• FlyBaseID: FBgn0030316
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_003402.2
• Gene: ZFY / 7544
• HGNCID: 12870
• Length: 801
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 118/572 - (20%)
• Similarity: 195/572 - (34%)
• Gaps: 190/572 - (33%)

  Fly    68 CAMVMKKQLGLQQLKMEPFSEDEDADTKAQILCEPEIDVSPAAADNEECNEIDGDASSNSRSSSI 132
            |..|:|..:    .|.:| .||:...|...:..|||.|......|               ::|||
Human   243 CPEVIKVYI----FKADP-GEDDLGGTVDIVESEPENDHGVELLD---------------QNSSI 287

  Fly   133 RTTSLREMRLPSPIRRRMR-------------LPRAVTAPKTQAVKAKARTKTHKAEADEDE--- 181
            |..  ||..:...:....:             :...|...:..|..|.|....|:.:.||||
Human   288 RVP--REKMVYMTVNDSQQEDEDLNVAEIADEVYMEVIVGEEDAAVAAAAAAVHEQQIDEDEMKT 350

  Fly   182 ------------DAEGEGDPESRSSNSREMDSYIALHGRL------------------------- 209
                        :::|..:....:|....:|....| |||
Human   351 FVPIAWAAAYGNNSDGIENRNGTASALLHIDESAGL-GRLAKQKPKKKRRPDSRQYQTAIIIGPD 414

  Fly   210 -------ECCICGGDEQFPNFAEMKRHFRNHHQSLG----------------------------- 238
                   .|.|||  ::|.:...:|||.:||.:.|.
Human   415 GHPLTVYPCMICG--KKFKSRGFLKRHMKNHPEHLAKKKYHCTDCDYTTNKKISLHNHLESHKLT 477

  Fly   239 -----YVVC--CQRRYKKRALYVDHLHMHNDP---NYFRCKICSKQLVSRISYDVHMLRFHPNKD 293
                 .:.|  |.:.:........|..:|.:.   ...:||.|..:...:...:.|:|..|  ..
Human   478 SKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVH--SK 540

  Fly   294 DLSFACDQCSKRFSKQFLLTIHSRVHQQERNEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFICD 358
            :....|.:|.|.|.....|..|.|:|..|:..||::|:.....:.:|:.|::..|... :||.||
Human   541 NFPHICVECGKGFRHPSELRKHMRIHTGEKPYQCQYCEYRSADSSNLKTHIKTKHSKE-MPFKCD 604

  Fly   359 SCGAKF----KTKQNLLVHKRT-VHREGSQLPEVQCQECQVWLSDENSLRKHM-------YMHLD 411
            .|...|    :.:|:.|||:.: .|         ||..|....|:.:.|::|:       |.|
Human   605 ICLLTFSDTKEVQQHTLVHQESKTH---------QCLHCDHKSSNSSDLKRHVISVHTKDYPH-- 658

  Fly   412 AASLRQWKCEQCGLEKGSR--AKLAAHIRYHHPKEYHKCTH------------------------ 450
                   |||.|  |||..  ::|..|:..|..|:.|:|.|
Human   659 -------KCEMC--EKGFHRPSELKKHVAVHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLP 714

  Fly   451 -----CAKEFKSSRSLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMH 497
                 |.|.|:....|::|..||:|:.:|:|.:||.:..::....:|...:|
Human   715 FRCKRCRKGFRQQNELKKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIH 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:462262	3/12 (25%)
		C2H2 Zn finger	268..289	CDD:275368	5/20 (25%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		SUF4-like	327..>387	CDD:411020	16/64 (25%)
		C2H2 Zn finger	327..348	CDD:411020	4/20 (20%)
		C2H2 Zn finger	327..348	CDD:275368	4/20 (20%)
		C2H2 Zn finger	357..378	CDD:411020	8/25 (32%)
		C2H2 Zn finger	357..376	CDD:275368	8/22 (36%)
		C2H2 Zn finger	389..409	CDD:275368	6/26 (23%)
		C2H2 Zn finger	420..440	CDD:275368	8/21 (38%)
		C2H2 Zn finger	448..468	CDD:275368	7/48 (15%)
		C2H2 Zn finger	476..494	CDD:275368	4/17 (24%)
ZFY	NP_003402.2	Zfx_Zfy_act	71..406	CDD:461400	35/185 (19%)
		COG5048	<417..592	CDD:227381	35/178 (20%)
		C2H2 Zn finger	423..443	CDD:275368	8/21 (38%)
		C2H2 Zn finger	454..478	CDD:275368	0/23 (0%)
		C2H2 Zn finger	486..506	CDD:275368	3/19 (16%)
		COG5048	539..>676	CDD:227381	42/157 (27%)
		C2H2 Zn finger	546..566	CDD:275368	7/19 (37%)
		zf-H2C2_2	558..582	CDD:463886	8/23 (35%)
		C2H2 Zn finger	574..593	CDD:275368	4/18 (22%)
		C2H2 Zn finger	603..652	CDD:275368	15/57 (26%)
		C2H2 Zn finger	660..680	CDD:275368	8/21 (38%)
		zf-C2H2	715..737	CDD:395048	5/21 (24%)
		C2H2 Zn finger	717..737	CDD:275368	5/19 (26%)
		zf-H2C2_2	729..753	CDD:463886	9/23 (39%)
		C2H2 Zn finger	745..766	CDD:275368	4/20 (20%)
		C2H2 Zn finger	774..794	CDD:275368