DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11695 and znf740a

DIOPT Version :9

Sequence 1:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	XP_005172837.1	Gene:	znf740a / 571608	ZFINID:	ZDB-GENE-030131-5064	Length:	543	Species:	Danio rerio

Alignment Length:	337	Identity:	78/337 - (23%)
Similarity:	126/337 - (37%)	Gaps:	48/337 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 CCICGGDEQFPNFAEMKRHFRNHHQSLGYV-VCCQRRYKKRALYVDHLHMHNDPNYFRCKICSKQ 274
            |.:|  |.:|.....::||...|.....|. ..|..|:.:|.....|..:|.....:.|.:|.::
Zfish   204 CSMC--DMRFFQRYHLERHSLTHTGVKPYACTMCDMRFFQRYHLQRHSLIHTGVKPYACSMCDRR 266

  Fly   275 LVSRISYDVHML-------------------RFHPNKDDLS------FACDQCSKRFSKQFLLTI 314
            ...|.....|.|                   |:|..:..|:      |||..|..||.:::.|..
Zfish   267 FFQRYHLQRHSLTHTGVKPYACSICDMRFFQRYHLQRHSLTHTGVKPFACTMCDMRFFQRYHLQR 331

  Fly   315 HSRVHQQERNEQCKHCDRSFRTAVDLRLHMRR---THDPAFVPFICDSCGAKFKTKQNLLVHKRT 376
            ||..|...:...|..||..|..    |.|::|   || ....|:.|..|..:|..:.:|..|..|
Zfish   332 HSITHTGVKPYACSMCDMRFFH----RYHLQRHSLTH-TGVKPYACTMCDMRFFQRYHLQRHSLT 391

  Fly   377 VHREGSQLPEVQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHH 441
             |   :.:....|..|.:.......|::|...|   ..::.:.|..|.:....|..|..|...|.
Zfish   392 -H---TGVKPYACSMCDMRFFQRYHLQRHSLTH---TGVKPYACSMCDMRFFQRYHLERHSLTHT 449

  Fly   442 PKEYHKCTHCAKEFKSSRSLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQVAALQQ 506
            .::...|..|...|.....||.|...|:|:..|:|..|::.|..:..:.:|||......|..::.
Zfish   450 GEKPFACDMCDMRFIQRYHLERHKRVHSGEKPYQCERCQQNFSRTDRLLRHRRLCQGRGVTKVEA 514

  Fly   507 Q-----KKVPPS 513
            |     ::.||:
Zfish   515 QPCPYTQEPPPA 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071
		C2H2 Zn finger	268..289	CDD:275368	6/39 (15%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..348	CDD:275368	7/23 (30%)
		C2H2 Zn finger	357..376	CDD:275368	5/18 (28%)
		C2H2 Zn finger	389..409	CDD:275368	4/19 (21%)
		C2H2 Zn finger	420..440	CDD:275368	5/19 (26%)
		C2H2 Zn finger	448..468	CDD:275368	6/19 (32%)
		C2H2 Zn finger	476..494	CDD:275368	4/17 (24%)
znf740a	XP_005172837.1	COG5048	138..503	CDD:227381	73/312 (23%)
		C2H2 Zn finger	148..168	CDD:275368
		C2H2 Zn finger	176..196	CDD:275368
		C2H2 Zn finger	204..224	CDD:275368	6/21 (29%)
		C2H2 Zn finger	232..252	CDD:275368	4/19 (21%)
		C2H2 Zn finger	260..280	CDD:275368	5/19 (26%)
		C2H2 Zn finger	288..308	CDD:275368	3/19 (16%)
		C2H2 Zn finger	316..336	CDD:275368	7/19 (37%)
		C2H2 Zn finger	344..364	CDD:275368	7/23 (30%)
		C2H2 Zn finger	372..392	CDD:275368	6/20 (30%)
		C2H2 Zn finger	400..420	CDD:275368	4/19 (21%)
		C2H2 Zn finger	428..448	CDD:275368	5/19 (26%)
		C2H2 Zn finger	456..476	CDD:275368	6/19 (32%)
		C2H2 Zn finger	484..503	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100