DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11695 and Zfp410

DIOPT Version :9

Sequence 1:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_659082.1	Gene:	Zfp410 / 52708	MGIID:	1289280	Length:	478	Species:	Mus musculus

Alignment Length:	222	Identity:	51/222 - (22%)
Similarity:	84/222 - (37%)	Gaps:	47/222 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 QQERNEQC--KHCDRSFRTAVDLRLHMRRTHDPAFVPFIC--DSCGAKFKTKQNLLVHKRTVHRE 380
            |.|:..:|  :.|||:|......:.|::...:..  .|||  :.||..|...|.|.||.||.:.|
Mouse   214 QAEKKLKCTVEGCDRTFVWPAHFKYHLKTHRNER--SFICPAEGCGKSFYVLQRLKVHMRTHNGE 276

  Fly   381 GSQLPEVQCQE--CQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHHPK 443
                ....|.|  |....:...:|:.|..:|   ...:.:.||..|
Mouse   277 ----KPFMCHESGCGKQFTTAGNLKNHRRIH---TGEKPFLCEAQG------------------- 315

  Fly   444 EYHKCTHCAKEFKSSRSLEEHTATHTGQDLYECAFCERTFKNSG--NMHKHRRQMHAAQVAALQQ 506
                   |.:.|....||.:|...|:|:..::|..|.:||..||  |:|..:..:......:.:|
Mouse   316 -------CGRSFAEYSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGTTGSQEQ 373

  Fly   507 QKKVPPSKRKDKGDLLLDVLAAGGKDM 533
            .:...|.    .|..||:..:...|::
Mouse   374 DQTAEPL----MGSSLLEDASVPNKNL 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071
		C2H2 Zn finger	268..289	CDD:275368
		C2H2 Zn finger	299..319	CDD:275368
		C2H2 Zn finger	327..348	CDD:275368	6/22 (27%)
		C2H2 Zn finger	357..376	CDD:275368	8/20 (40%)
		C2H2 Zn finger	389..409	CDD:275368	5/21 (24%)
		C2H2 Zn finger	420..440	CDD:275368	3/19 (16%)
		C2H2 Zn finger	448..468	CDD:275368	5/19 (26%)
		C2H2 Zn finger	476..494	CDD:275368	8/19 (42%)
Zfp410	NP_659082.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	84..113
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..214		51/222 (23%)
		SFP1	<189..300	CDD:227516	25/91 (27%)
		C2H2 Zn finger	221..243	CDD:275368	6/21 (29%)
		C2H2 Zn finger	251..273	CDD:275368	9/21 (43%)
		zf-H2C2_2	265..292	CDD:372612	9/30 (30%)
		C2H2 Zn finger	281..303	CDD:275368	5/21 (24%)
		zf-H2C2_2	295..321	CDD:372612	7/54 (13%)
		C2H2 Zn finger	311..333	CDD:275368	8/47 (17%)
		zf-H2C2_2	325..350	CDD:372612	9/24 (38%)
		C2H2 Zn finger	341..361	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100