DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11695 and CG6791

DIOPT Version :9

Sequence 1:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_650090.1	Gene:	CG6791 / 41391	FlyBaseID:	FBgn0037918	Length:	1243	Species:	Drosophila melanogaster

Alignment Length:	629	Identity:	127/629 - (20%)
Similarity:	191/629 - (30%)	Gaps:	271/629 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 CTQCWQQLADFEQFCAMVMKKQLGLQQLKMEPF----SEDEDADTKAQILCEPEIDVSPAAADNE 114
            |..|::...|.::....:      |||..|:..    :|:||.|             :|:|.: :
  Fly   425 CKLCYKGYTDHQEIIRHL------LQQHHMDTLMSEDAEEEDGD-------------APSAIE-D 469

  Fly   115 ECNEIDGDASSNSRSSSIRTTSLREMRLPSPIRRRMRLPRAVTAPKTQAVKAKARTKTHKAEADE 179
            ||:..:|:...|.                                               |..||
  Fly   470 ECDGDNGNGEGNG-----------------------------------------------APLDE 487

  Fly   180 D----EDAEGEGDPESRSSNSREMDSYIALHGRLECCICGGDEQFPNFAEMKRHFRNH----H-- 234
            |    |||...|   .|.|:    |.....|....|..||.:     |.| |:|:|.|    |
  Fly   488 DSPYFEDAPRRG---GRISS----DDIFEPHIDYLCPQCGKE-----FIE-KKHWRTHVVMAHSM 539

  Fly   235 ---QSLGYVVCCQRRYK--------KRALYVDHLHMHNDPN-----YFRCKICSKQLVSRISYDV 283
               ..|.:.:..:|:.|        ..|..:.:...|...:     |.||:.|.|....|.....
  Fly   540 NDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVK 604

  Fly   284 HMLRFH----PNKDDLSFACD----QCSKRFSKQFLLTIHSRVH--------------------- 319
            |:...|    |.|  ||..|.    ..:|:..|| ::|:.:..:
  Fly   605 HLATHHRVGWPRK--LSGGCPAPILTPAKQPRKQ-IVTVANETYEIIYLDDVDQGGMEEDNDFGE 666

  Fly   320 --QQERNE-------------------------QCKHCDRSFRTAVDLRLH----------MRRT 347
              |.|.:|                         :|.||...|.|...:|:|          :||.
  Fly   667 QMQAEEDEYPIAPPPPSPPPPPQPTTQGNHQRYKCVHCGTLFATQAAVRVHISEKRCRKTVVRRR 731

  Fly   348 HDPAF------VP-------FICDSCGAKFKTKQNLLVHKRTVH----REGSQLPEV-----QCQ 390
            ..|..      ||       |:|.|||.::||:.....|...||    |:...:.::     ||.
  Fly   732 RQPVMSSADPSVPTVEQNYIFLCPSCGFEYKTQFEWRRHINEVHNFDKRQYLNMRQLDKYRYQCT 796

  Fly   391 ECQ--VWLSDENSLRKHMYMHLDAASLRQW-KCEQCGLEKGSRAKLAAHIRYHH----------- 441
            :|:  |..|....|:.|.:.||   ..|.: ||..||.....:..:|||:|..|
  Fly   797 QCKDIVCNSKLKGLQDHHFRHL---PYRLYLKCLICGTCYNHKPNIAAHLRARHSIFDRETPTMI 858

  Fly   442 --PKEY---HK---------------------------CTHCAKEFKSSRS-------------- 460
              ||:.   :|                           |:..|....||||
  Fly   859 TKPKQVLGRYKDNSRENPKLPSPPPAPALAPAPPSPPACSSSAAASASSRSLKPQPGGLPARPAG 923

  Fly   461 ---LEEHTATHTGQDL----YECAFCERTFKNSGNMHKHRRQMH 497
               ||:..:.|...||    |.|..|.:.|.:.....||..:.|
  Fly   924 LNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQH 967

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071	5/26 (19%)
		C2H2 Zn finger	268..289	CDD:275368	5/20 (25%)
		C2H2 Zn finger	299..319	CDD:275368	5/23 (22%)
		C2H2 Zn finger	327..348	CDD:275368	9/30 (30%)
		C2H2 Zn finger	357..376	CDD:275368	7/18 (39%)
		C2H2 Zn finger	389..409	CDD:275368	6/21 (29%)
		C2H2 Zn finger	420..440	CDD:275368	7/19 (37%)
		C2H2 Zn finger	448..468	CDD:275368	8/36 (22%)
		C2H2 Zn finger	476..494	CDD:275368	5/17 (29%)
CG6791	NP_650090.1	C2H2 Zn finger	167..188	CDD:275368
		C2H2 Zn finger	208..230	CDD:275368
		C2H2 Zn finger	235..256	CDD:275368
		C2H2 Zn finger	516..532	CDD:275368	8/21 (38%)
		C2H2 Zn finger	557..580	CDD:275368	2/22 (9%)
		C2H2 Zn finger	589..609	CDD:275368	5/19 (26%)
		COG5236	<939..>1096	CDD:227561	8/29 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455514
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930