DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11695 and CG8944

DIOPT Version :9

Sequence 1:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_573065.1	Gene:	CG8944 / 32517	FlyBaseID:	FBgn0030680	Length:	762	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	70/308 - (22%)
Similarity:	121/308 - (39%)	Gaps:	51/308 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 RNHHQSLGYVVCCQRRYKKRALYVDHLH-MHNDPNYFRCKICSKQLVSRISYDVHMLRFHPNKDD 294
            |.:.:.||      :::....||.|.:| |.:|...|:|..|.:.:.:....|:|||...|:...
  Fly   444 RLNSERLG------KKFIANYLYYDQMHFMDDDIPPFKCAHCPEIVQTLRELDLHMLTHQPSLGG 502

  Fly   295 LSFACDQCSKRFSKQFLLTIHSRVH---QQERNEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFI 356
             .:.|:.||.:|........|.::|   ..|....|:.|..|||...:...|:||.::..|:|.:
  Fly   503 -GYYCNICSIQFHNAQEFDNHKQLHLGGVTEIKFNCELCTASFREKANYDEHLRRHNEELFLPSL 566

  Fly   357 C------------DSCGAKFKTKQNLLVHKRTVHRE------------------------GSQLP 385
            .            |..|.:.:..:.....::..|..                        |:.:.
  Fly   567 ALNHSIMEGGLGDDEIGVEGEESRGSGSRRKRRHAAKATDDMVDDDDRIGGGGGGGSGGGGTDIA 631

  Fly   386 E-VQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCE--QCGLEKGSRAKLAAHIRYHHPKEYHK 447
            : ..|..|:...:....|..|..:|.|... |.:||:  ||.....:|..|..|::.|:..|..|
  Fly   632 KPYGCDVCRRSFATPGHLNAHRIVHQDERE-RCYKCDYPQCNKSFVARNSLFEHLKQHYSNEEFK 695

  Fly   448 CTHCAKEFKSSRSLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQ 495
            |..|.|.|||:::|:.|...|.....|.|..|...|..:..::.|:|:
  Fly   696 CDICGKTFKSTKNLQNHKQIHDKIKRYVCQICGSAFAQAAGLYLHKRR 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071
		C2H2 Zn finger	268..289	CDD:275368	6/20 (30%)
		C2H2 Zn finger	299..319	CDD:275368	5/19 (26%)
		C2H2 Zn finger	327..348	CDD:275368	8/20 (40%)
		C2H2 Zn finger	357..376	CDD:275368	2/30 (7%)
		C2H2 Zn finger	389..409	CDD:275368	4/19 (21%)
		C2H2 Zn finger	420..440	CDD:275368	6/21 (29%)
		C2H2 Zn finger	448..468	CDD:275368	8/19 (42%)
		C2H2 Zn finger	476..494	CDD:275368	4/17 (24%)
CG8944	NP_573065.1	MADF_DNA_bdg	259..344	CDD:287510
		MADF	379..472	CDD:214738	9/33 (27%)
		C2H2 Zn finger	476..496	CDD:275368	6/19 (32%)
		C2H2 Zn finger	506..526	CDD:275368	5/19 (26%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	636..656	CDD:275368	4/19 (21%)
		zf-C2H2_8	639..712	CDD:292531	23/73 (32%)
		C2H2 Zn finger	666..688	CDD:275368	6/21 (29%)
		zf-C2H2	694..716	CDD:278523	9/21 (43%)
		C2H2 Zn finger	696..716	CDD:275368	8/19 (42%)
		zf-H2C2_2	708..733	CDD:290200	7/24 (29%)
		C2H2 Zn finger	724..744	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030