DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11695 and Zfp160

DIOPT Version :9

Sequence 1:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_663458.2	Gene:	Zfp160 / 224585	MGIID:	108187	Length:	650	Species:	Mus musculus

Alignment Length:	335	Identity:	88/335 - (26%)
Similarity:	135/335 - (40%)	Gaps:	49/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 SYIALHGR-------LECCICGGDEQFPNFAEMKRHFRNHHQSLGYVVC--CQRRYKKRALYVDH 256
            ||:.:|.|       .:|..||  :.|...:.:|.|.|.|.....: .|  |.:.:..|:....|
Mouse   187 SYLLVHERHHTGAKPYKCNECG--KVFSQNSHLKSHRRIHTGEKPF-KCNHCGKAFSVRSNLTHH 248

  Fly   257 LHMHNDPNYFRCKICSKQLVSRISYDVHMLRFHPNKDDLSFACDQCSKRFSKQFLLTIHSRVHQQ 321
            ..:|.....::|..|.|......|..:|. |.|..  :..:.|::|.|.||....|..|..:|..
Mouse   249 QVIHTGDKPYKCNECGKVFSQTSSLTIHR-RTHTG--EKPYRCNECGKVFSSHSNLNTHQAIHTG 310

  Fly   322 ERNEQCKHCDRSFRTAVDLRLHMR-----------------------RTHDPAFV---PFICDSC 360
            |:..:|..|.:.|.....|..|.|                       .||.....   |:.|:.|
Mouse   311 EKPYKCSECGKVFTQNSHLANHWRIHTGEKPYKCNECGKAFSVYSSLTTHQAIHTGEKPYKCNEC 375

  Fly   361 GAKFKTKQNLLVHKRTVHREGSQLPEVQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGL 425
            |..|....:|..| |.||  ..:.| .:|:||....|..::|.:|..:|   ...:.:||.:||.
Mouse   376 GKVFTQNSHLASH-RGVH--SGEKP-YKCEECGKLFSQTSNLARHWRVH---TGEKPYKCSECGK 433

  Fly   426 EKGSRAKLAAHIRYHHPKEYHKCTHCAKEFKSSRSLEEHTATHTGQDLYECAFCERTFKNSGNMH 490
            ....|:.|.||...|..::.:|||.|.|.|..:.||..|...|||:..|.|..|.:.|.:..|::
Mouse   434 AFSVRSSLIAHQVIHTGEKPYKCTECGKVFSQTSSLSIHQRIHTGEKPYRCNECGKAFNSHSNLN 498

  Fly   491 KHRRQMHAAQ 500
            .| :.:|..|
Mouse   499 TH-QVIHTGQ 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071
		C2H2 Zn finger	268..289	CDD:275368	6/20 (30%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..348	CDD:275368	6/43 (14%)
		C2H2 Zn finger	357..376	CDD:275368	6/18 (33%)
		C2H2 Zn finger	389..409	CDD:275368	6/19 (32%)
		C2H2 Zn finger	420..440	CDD:275368	7/19 (37%)
		C2H2 Zn finger	448..468	CDD:275368	8/19 (42%)
		C2H2 Zn finger	476..494	CDD:275368	5/17 (29%)
Zfp160	NP_663458.2	KRAB	8..68	CDD:214630
		KRAB	8..47	CDD:279668
		C2H2 Zn finger	148..168	CDD:275368
		C2H2 Zn finger	176..196	CDD:275368	4/8 (50%)
		zf-H2C2_2	188..213	CDD:290200	7/26 (27%)
		COG5048	200..635	CDD:227381	84/322 (26%)
		zf-C2H2	202..224	CDD:278523	7/23 (30%)
		C2H2 Zn finger	204..224	CDD:275368	7/21 (33%)
		zf-H2C2_2	216..240	CDD:290200	6/24 (25%)
		C2H2 Zn finger	232..252	CDD:275368	4/19 (21%)
		zf-H2C2_2	244..269	CDD:290200	5/24 (21%)
		C2H2 Zn finger	260..280	CDD:275368	6/20 (30%)
		zf-H2C2_2	272..297	CDD:290200	8/27 (30%)
		C2H2 Zn finger	288..308	CDD:275368	7/19 (37%)
		zf-H2C2_2	300..325	CDD:290200	7/24 (29%)
		C2H2 Zn finger	316..336	CDD:275368	6/19 (32%)
		C2H2 Zn finger	344..364	CDD:275368	2/19 (11%)
		zf-H2C2_2	356..381	CDD:290200	7/24 (29%)
		C2H2 Zn finger	372..392	CDD:275368	7/20 (35%)
		zf-H2C2_2	384..409	CDD:290200	9/28 (32%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		zf-H2C2_2	412..436	CDD:290200	7/26 (27%)
		C2H2 Zn finger	428..448	CDD:275368	7/19 (37%)
		zf-H2C2_2	440..465	CDD:290200	10/24 (42%)
		C2H2 Zn finger	456..476	CDD:275368	8/19 (42%)
		zf-H2C2_2	468..493	CDD:290200	10/24 (42%)
		C2H2 Zn finger	484..504	CDD:275368	5/20 (25%)
		zf-H2C2_2	496..521	CDD:290200	4/13 (31%)
		C2H2 Zn finger	512..532	CDD:275368
		zf-H2C2_2	524..548	CDD:290200
		C2H2 Zn finger	540..560	CDD:275368
		zf-H2C2_2	552..577	CDD:290200
		C2H2 Zn finger	568..588	CDD:275368
		zf-H2C2_2	580..604	CDD:290200
		C2H2 Zn finger	596..616	CDD:275368
		zf-H2C2_2	608..633	CDD:290200
		C2H2 Zn finger	624..644	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832269
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930