Protein Alignment CG11695 and E4F1

DIOPT Version :9

• Sequence 1: NP_572732.1
• Gene: CG11695 / 32106
• FlyBaseID: FBgn0030316
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_005255212.1
• Gene: E4F1 / 1877
• HGNCID: 3121
• Length: 837
• Species: Homo sapiens
• Alignment Length: 664
• Identity: 122/664 - (18%)
• Similarity: 187/664 - (28%)
• Gaps: 248/664 - (37%)

  Fly    22 SGDQPVPSNLAELIEKHLQLVLLPNDGVSKSLCTQCWQQLADFEQFCAMVMKKQ----------- 75
            |.|.|.|.:||:|.... |....|.|......|.:|..:....|.|....::|.
Human    82 STDPPRPRHLADLAGPS-QPSTKPPDEDDVHRCGRCQAEFTALEDFVQHKIQKACQRAPPEALPA 145

  Fly    76 -------LGLQQLKMEPFSEDEDADTKAQILCEPEIDVSPAAADNEECNEIDGDASSNSRSSSIR 133
                   ||.:.:...|  ..|:..|.|.|:    ::.:..|||....:::.|..
Human   146 TPATTALLGQEVVPAAP--GPEEPITVAHIV----VEAASLAADISHASDLVGGG---------- 194

  Fly   134 TTSLREMRLPSPIRRRMRLPRAVTAPKTQAVKAKARTKTHKAEADEDEDAEGEGDPESR------ 192
                             .:...:.|.              :||..:.|.||..|.|..:
Human   195 -----------------HIKEVIVAA--------------EAELGDGEMAEAPGSPRQQGLGLAG 228

  Fly   193 SSNSREMDSYIALHGRLECCICGGDEQFPNFAEMKRHFRNH-----HQSLGYVVC--CQRRYKKR 250
            .....::...:...||..|.:|  .:.|...:.:|.|...|     |:      |  |...::.:
Human   229 EGEQAQVKLLVNKDGRYVCALC--HKTFKTGSILKAHMVTHSSRKDHE------CKLCGASFRTK 285

  Fly   251 ALYVDHLHMHNDPNYFRCKICSKQLVSRISYDVHM---------LRFHPNKD------------- 293
            ...:.|...|.|...::|..|.|......:...|:         :||..:||
Human   286 GSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDARAGSG 350

  Fly   294 -------------------------------------------DLSFACD------------QCS 303
                                                       :||....            .||
Human   351 AGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCS 415

  Fly   304 KRFSKQFLL---------------------------------------------------TIHSR 317
            ...|::.||                                                   .:.|.
Human   416 SEGSRENLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLAVAAPQLPVLEVQPLETQVASE 480

  Fly   318 VHQQERNEQCKHCDRSFRTAVDLRLHMRRTHDPAFVPFICDSCGAKFKTKQNLLVHKRTVH-REG 381
            .....|...|..|..:|.||..|..|.|....|.  ||.|..||..| .|..||...:.|| ||
Human   481 ASAVPRTHPCPQCSETFPTAATLEAHKRGHTGPR--PFACAQCGKAF-PKAYLLKKHQEVHVRE- 541

  Fly   382 SQLPEVQCQECQVWLSDENSLRKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHHPKEYH 446
               ...:|.:|.........:|.|..:|.|.   |.:.|.:||....::.....|.|.|..::.|
Human   542 ---RRFRCGDCGKLYKTIAHVRGHRRVHSDE---RPYPCPKCGKRYKTKNAQQVHFRTHLEEKPH 600

  Fly   447 KCTHCAKEFKSSRSLEEHTATHTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQVAALQQQKKVP 511
            .|..|::.|:...||..|...|||:..::|..|.|.|...|.:::|.|
Human   601 VCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRHLR----------------- 648

  Fly   512 PSKRKDKGDLLLDV 525
                 .||..||:|
Human   649 -----TKGGCLLEV 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071	17/76 (22%)
		C2H2 Zn finger	268..289	CDD:275368	5/29 (17%)
		C2H2 Zn finger	299..319	CDD:275368	6/82 (7%)
		C2H2 Zn finger	327..348	CDD:275368	8/20 (40%)
		C2H2 Zn finger	357..376	CDD:275368	7/18 (39%)
		C2H2 Zn finger	389..409	CDD:275368	4/19 (21%)
		C2H2 Zn finger	420..440	CDD:275368	5/19 (26%)
		C2H2 Zn finger	448..468	CDD:275368	6/19 (32%)
		C2H2 Zn finger	476..494	CDD:275368	6/17 (35%)
E4F1	XP_005255212.1	COG5048	236..648	CDD:227381	82/429 (19%)
		C2H2 Zn finger	247..267	CDD:275368	5/21 (24%)
		zf-C2H2	273..295	CDD:278523	4/27 (15%)
		C2H2 Zn finger	275..295	CDD:275368	3/19 (16%)
		zf-H2C2_2	287..310	CDD:290200	6/22 (27%)
		zf-C2H2	301..322	CDD:278523	4/20 (20%)
		C2H2 Zn finger	303..321	CDD:275368	4/17 (24%)
		C2H2 Zn finger	490..510	CDD:275368	8/19 (42%)
		DUF45	<506..585	CDD:302795	26/88 (30%)
		C2H2 Zn finger	518..538	CDD:275368	7/20 (35%)
		C2H2 Zn finger	546..566	CDD:275368	4/19 (21%)
		zf-H2C2_2	558..583	CDD:290200	8/27 (30%)
		C2H2 Zn finger	574..594	CDD:275368	5/19 (26%)
		zf-H2C2_2	588..609	CDD:290200	6/20 (30%)
		C2H2 Zn finger	602..622	CDD:275368	6/19 (32%)
		zf-H2C2_2	614..638	CDD:290200	9/23 (39%)
		C2H2 Zn finger	630..649	CDD:275368	7/40 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100