DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11695 and ztf-23

DIOPT Version :9

Sequence 1:	NP_572732.1	Gene:	CG11695 / 32106	FlyBaseID:	FBgn0030316	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_491096.1	Gene:	ztf-23 / 171880	WormBaseID:	WBGene00021846	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	295	Identity:	57/295 - (19%)
Similarity:	87/295 - (29%)	Gaps:	138/295 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 YVDHL------HMHNDPNYFRCKICSKQLVSRISYDVHM--------------------LRFHPN 291
            |:|.|      ..|:|.:|......|.|...|.|.:.|:                    .|..|.
Worm   161 YIDELGNPVFIGAHDDSDYILEDDLSPQGPIRSSNNYHLKYIRTRRMDKLIDNVVVNATQRDSPE 225

  Fly   292 KDDLS------------------FACDQCSKRFSKQFLLTIHSRVHQQERNEQCKHCDRSFRTAV 338
            ::|.|                  |:||:||:.|..|..|..|.|.|...:..||.:|.|.|....
Worm   226 QEDCSTSGVAFADGQTNSGKMGRFSCDRCSRTFKYQSKLDEHRRTHLGVKPFQCHYCTRQFSQRG 290

  Fly   339 DLRLHMR-RTHDPAFVPFICDSCGAKFKTKQNLLVHKRTVHREGSQLPEVQCQECQVWLSDENSL 402
            .|:.||| .|.:.   ||:|
Worm   291 ALKTHMRLHTGER---PFVC--------------------------------------------- 307

  Fly   403 RKHMYMHLDAASLRQWKCEQCGLEKGSRAKLAAHIRYHHPKEYHKCTHCAKEFKSSRSLEEHTAT 467
                          ||:                               |.|:|.||.:...|..|
Worm   308 --------------QWE-------------------------------CGKQFASSSAKSHHEKT 327

  Fly   468 HTGQDLYECAFCERTFKNSGNMHKHRRQMHAAQVA 502
            |:|:..|.|..|.::|..:.::.:|.:.:|..::|
Worm   328 HSGERPYICNVCGKSFTKNSHVIRHLKNIHNRELA 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11695	NP_572732.1	zf-AD	2..81	CDD:285071
		C2H2 Zn finger	268..289	CDD:275368	6/40 (15%)
		C2H2 Zn finger	299..319	CDD:275368	9/19 (47%)
		C2H2 Zn finger	327..348	CDD:275368	8/21 (38%)
		C2H2 Zn finger	357..376	CDD:275368	1/18 (6%)
		C2H2 Zn finger	389..409	CDD:275368	0/19 (0%)
		C2H2 Zn finger	420..440	CDD:275368	0/19 (0%)
		C2H2 Zn finger	448..468	CDD:275368	6/19 (32%)
		C2H2 Zn finger	476..494	CDD:275368	4/17 (24%)
ztf-23	NP_491096.1	C2H2 Zn finger	251..271	CDD:275368	9/19 (47%)
		zf-H2C2_2	264..288	CDD:290200	9/23 (39%)
		C2H2 Zn finger	279..299	CDD:275368	8/19 (42%)
		zf-H2C2_2	291..317	CDD:290200	13/118 (11%)
		C2H2 Zn finger	307..328	CDD:275368	9/110 (8%)
		zf-H2C2_2	324..344	CDD:290200	7/19 (37%)
		C2H2 Zn finger	336..357	CDD:275368	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000