DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11696 and ZNF692

DIOPT Version :9

Sequence 1:NP_572731.1 Gene:CG11696 / 32104 FlyBaseID:FBgn0030314 Length:664 Species:Drosophila melanogaster
Sequence 2:XP_011542525.1 Gene:ZNF692 / 55657 HGNCID:26049 Length:625 Species:Homo sapiens


Alignment Length:674 Identity:126/674 - (18%)
Similarity:184/674 - (27%) Gaps:323/674 - (47%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 HGVPIFGQEPPMGQPAHRQLAELIERHLLLVLAENDV-VSTC----LCNRCWRQLAEIEQFCSMV 71
            ||..:    ||.|...           ||..||...| |...    ||..|.|:       ||:|
Human   206 HGAVV----PPQGAAG-----------LLPALAARQVPVGPVHFFRLCPLCSRE-------CSLV 248

  Fly    72 AEKQRSLHRSLQLKTELPELPELTEP--EPALVVWN-----------------TESPIEPKLSY- 116
                                |.|..|  :...:||.                 :|:|....|.: 
Human   249 --------------------PGLRGPGGQDGGLVWECSAGHTFSWGPSLSPTPSEAPKPASLPHT 293

  Fly   117 ----------EGDDIKDHILCEPVIDALSAGDEKDSDYGDTFEPDFEPESQPDEEEEPE--PDPV 169
                      .|.::.|                .:|::.:..:....|.|:||   .|.  |.||
Human   294 TRRSWCSEATSGQELAD----------------LESEHDERTQEARLPSSEPD---APRLLPSPV 339

  Fly   170 KPRPR-GR--PRKTALQQTHQIIKRKYEKRKQQNKAKITELSLRESRAR---------QRELKRS 222
            ...|: |.  |...||                .:...:..||.....:|         |.:|.| 
Human   340 TCTPKEGETPPAPAAL----------------SSPLAVPALSASSLSSRAPPPAEVRVQPQLSR- 387

  Fly   223 SAGAEDDQDGDEDEEDEEDVGGELTPDADEQPKPRGKRGRPKTKKLVTADDNDDTSEVPVKRSSI 287
                                    ||.|.:|.:.....| .:.:...|...::||:::..||   
Human   388 ------------------------TPQAAQQTEALASTG-SQAQSAPTPAWDEDTAQIGPKR--- 424

  Fly   288 KEMDDYIAANVKLDCAICAAPLEDFNDLKRHFRVEHDCTGYVKCCNNRYKKRTLYVDHLHCHKDP 352
                  |....|.:...|..|                                            
Human   425 ------IRKAAKRELMPCDFP-------------------------------------------- 439

  Fly   353 QYFSCQSCRKNFLNRNSQVMHMLRFHSQQQELVHQCAICEARFAKKFLLTMHLKGHKGTERPEVC 417
                  .|.:.|.||     ..|..|.:.|. :||                     |....||  
Human   440 ------GCGRIFSNR-----QYLNHHKKYQH-IHQ---------------------KSFSCPE-- 469

  Fly   418 DTCSKTFRTKFELSAHVKRMHAADFTPIICDICGTHFRSKANFLIHKKALHPDGPVAEVQCTLCG 482
            ..|.|:|..|..|..|:| :| :|....||:.|...||:.:|.:||::....:.|   :||.:||
Human   470 PACGKSFNFKKHLKEHMK-LH-SDTRDYICEFCARSFRTSSNLVIHRRIHTGEKP---LQCEICG 529

  Fly   483 RWLRDERSLRKHLARHDDRDGDTKYRCLLCNAEKSSRAALSSHMRYHHSAKRHKCSLCDKEFKLP 547
            ...|.:.||..|..:|.:                 :.|||           |..|..|.|.|:.|
Human   530 FTCRQKASLNWHQRKHAE-----------------TVAAL-----------RFPCEFCGKRFEKP 566

  Fly   548 RALAEHMATHTGIDLYQCQFCTRTFKSHANMHNHKKKMHPNDWVRKYSQPSSSITSTAAPLAHPN 612
            .::|.                            |:.|.||              ....||...|:
Human   567 DSVAA----------------------------HRSKSHP--------------ALLLAPQESPS 589

  Fly   613 HPNQPAPPAAAPTNLAGHMLPPLG 636
            .|.:|.|..:||        .|||
Human   590 GPLEPCPSISAP--------GPLG 605

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11696NP_572731.1 zf-AD 2..78 CDD:285071 18/70 (26%)
C2H2 Zn finger 332..349 CDD:275368 0/16 (0%)
C2H2 Zn finger 357..378 CDD:275368 5/20 (25%)
C2H2 Zn finger 388..408 CDD:275368 0/19 (0%)
C2H2 Zn finger 417..438 CDD:275368 7/20 (35%)
C2H2 Zn finger 447..465 CDD:275368 7/17 (41%)
C2H2 Zn finger 478..498 CDD:275368 7/19 (37%)
C2H2 Zn finger 509..529 CDD:275368 3/19 (16%)
C2H2 Zn finger 537..557 CDD:275368 6/19 (32%)
C2H2 Zn finger 565..583 CDD:275368 1/17 (6%)
ZNF692XP_011542525.1 zf-C2H2 465..489 CDD:278523 9/26 (35%)
C2H2 Zn finger 467..489 CDD:275368 9/24 (38%)
COG5048 490..>591 CDD:227381 36/173 (21%)
zf-C2H2 495..517 CDD:278523 8/21 (38%)
C2H2 Zn finger 497..517 CDD:275368 7/19 (37%)
zf-H2C2_2 509..534 CDD:290200 8/27 (30%)
C2H2 Zn finger 525..545 CDD:275368 7/19 (37%)
C2H2 Zn finger 556..577 CDD:275368 8/48 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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