DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11696 and znf367

DIOPT Version :9

Sequence 1:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001017726.2	Gene:	znf367 / 550421	ZFINID:	ZDB-GENE-050417-231	Length:	316	Species:	Danio rerio

Alignment Length:	220	Identity:	51/220 - (23%)
Similarity:	71/220 - (32%)	Gaps:	73/220 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   474 AEVQCTLCGRWLRDERSLRKHLARHDD-----RDGD---TKYRCLLCNAEKSSRAALSSHMRYHH 530
            ||.....|...|:|  .:|:...|.|.     .:|:   ::.||.:||.......:|.:|.|.|.
Zfish    82 AEADPLSCPEHLKD--GIRRGRPRADTVRELINEGENSTSRIRCNICNRVFPREKSLQAHKRTHT 144

  Fly   531 SAKRHKCSL--CDKEFKLPRALAEHMATHTGIDLYQC--QFCTRTFKSHANMHNHK------KKM 585
            ..:.:.|..  |.|.|.....|..|...|||...:.|  :.|...| :|||.|..|      |:.
Zfish   145 GERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPFVCSEKACGSRF-THANRHCAKHPYARLKRE 208

  Fly   586 HPN---------------DWVRKYSQPSSSITSTAAPLAHPNHPNQPAPPAAAPTNLAGHMLPPL 635
            .|.               :|:.||.|              ......|.|..|.|.|
Zfish   209 EPTGGPGKSQGADNKAVAEWLTKYWQ--------------TREQRSPVPGKAKPQN--------- 250

  Fly   636 GGIAKSLIE----------IPDTEG 650
                ||.:|          :|..||
Zfish   251 ----KSPLEDQEQQDPLDFLPSDEG 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	332..349	CDD:275368
		C2H2 Zn finger	357..378	CDD:275368
		C2H2 Zn finger	388..408	CDD:275368
		C2H2 Zn finger	417..438	CDD:275368
		C2H2 Zn finger	447..465	CDD:275368
		C2H2 Zn finger	478..498	CDD:275368	4/19 (21%)
		C2H2 Zn finger	509..529	CDD:275368	6/19 (32%)
		C2H2 Zn finger	537..557	CDD:275368	6/21 (29%)
		C2H2 Zn finger	565..583	CDD:275368	8/25 (32%)
znf367	NP_001017726.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	61..97		5/16 (31%)
		COG5048	115..>182	CDD:227381	17/66 (26%)
		C2H2 Zn finger	123..143	CDD:275368	6/19 (32%)
		C2H2 Zn finger	151..173	CDD:275368	6/21 (29%)
		C2H2 Zn finger	181..200	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..294		12/65 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100