DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11696 and CG6813

DIOPT Version :9

Sequence 1:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	333	Identity:	77/333 - (23%)
Similarity:	110/333 - (33%)	Gaps:	101/333 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 LDCAICA---APLEDFNDLKRHF-RVEHDCTGYVKCCNNRYKKRTLYVDHLHCHKDPQYFSCQSC 360
            |:|.||:   ||::.|.....|. |..|..||.                .|.|.|:.....|.:|
  Fly     4 LNCRICSRSDAPIDLFGPGNGHLVRQIHSITGV----------------ELSCKKEISGQMCTTC 52

  Fly   361 RKNFLNRNSQVMHMLRFHSQQQELVHQCAICEARFAKKFLLTMHLKGHKGTERPEVCDT--CSK- 422
            ..|       :...::|.       .:|.|.|               .:..||.| ||:  ||.
  Fly    53 LDN-------LQAAIKFR-------QRCIIAE---------------KQNLERIE-CDSKDCSTD 87

  Fly   423 ----------------------------TFRTKFELSAHVKRMHAADF----TPIICDICGTHFR 455
                                        ...:..::||.....|....    .|.:|..||....
  Fly    88 PIIYEDIDDNQIESELDESILCPEVKDLPMPSAEKVSAPTSLNHQKSIGGGTGPYVCPDCGRIIN 152

  Fly   456 SKANFLIHKKALHPDGPVAEVQCTLCGRWLRDERSL--RKHLARHDD-RDGDTKYRCLLCNAEKS 517
            :|:||..|  .|...| :....|.    :|..|||.  ||.|..|.. ..|:..|.|:.|....|
  Fly   153 NKSNFQEH--TLRHTG-IKNFHCV----FLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFS 210

  Fly   518 SRAALSSHMRYHHSAKRHKCSLCDKEFKLPRALAEHMATHTGIDLYQCQFCTRTFK------SHA 576
            |..|...|.|.|.:.:|::|..|.|.|.....|.:|...|.....:.|..|.:.||      :|.
  Fly   211 SSGARQEHHRRHRNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHL 275

  Fly   577 NMHNHKKK 584
            :.:.||:|
  Fly   276 SSNIHKRK 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	332..349	CDD:275368	1/16 (6%)
		C2H2 Zn finger	357..378	CDD:275368	3/20 (15%)
		C2H2 Zn finger	388..408	CDD:275368	3/19 (16%)
		C2H2 Zn finger	417..438	CDD:275368	6/51 (12%)
		C2H2 Zn finger	447..465	CDD:275368	7/17 (41%)
		C2H2 Zn finger	478..498	CDD:275368	8/21 (38%)
		C2H2 Zn finger	509..529	CDD:275368	7/19 (37%)
		C2H2 Zn finger	537..557	CDD:275368	6/19 (32%)
		C2H2 Zn finger	565..583	CDD:275368	6/23 (26%)
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	21/114 (18%)
		C2H2 Zn finger	144..164	CDD:275368	8/21 (38%)
		C2H2 Zn finger	172..194	CDD:275368	9/25 (36%)
		zf-H2C2_2	186..211	CDD:290200	6/24 (25%)
		UFD2	<256..>294	CDD:227443	8/28 (29%)
		C2H2 Zn finger	258..280	CDD:275368	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000