DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11696 and CG31388

DIOPT Version :9

Sequence 1:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	625	Identity:	133/625 - (21%)
Similarity:	200/625 - (32%)	Gaps:	205/625 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ICRLCLEDAEHGVP--IFGQEPPMGQPAHRQLAELIERHLLLVLAENDVVSTCLCNRCWRQLAEI 64
            |||.|...|:..|.  :|       .|:...:...||....|.|.|:..:...:|..|...|...
  Fly     4 ICRTCSRMADPAVAKNLF-------DPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIA 61

  Fly    65 EQFCSMVAEKQRSLHRSLQLKTELPELPELTEPEPALVVWNTESPIEPKLSYEGDDIKDHIL-CE 128
            ..|..:..|.|..|  .|||:       ::.:.|.|.     ||..|..|    ||..|.:. ..
  Fly    62 IDFRRVCIEAQELL--ELQLR-------QVEKEEEAF-----ESLAEQWL----DDCPDELSNLS 108

  Fly   129 PVIDALSAGDEKDSDYGDTFEPDFEPESQPDEEEEPEPDPVKPRPRGRPRKTALQQTHQIIKRKY 193
            ||:           ...|..:..|:||.|....:|
  Fly   109 PVL-----------QLNDRMDFIFDPEPQDKNTDE------------------------------ 132

  Fly   194 EKRKQQNKAKITELSLRESRARQRELKRSSAGAEDDQDGDEDEEDEEDVGGELTPDADEQPKPRG 258
                   .|.|...:..|.....:.:....:..|...|.....| ..|:|  |:|:::.:.:
  Fly   133 -------LASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNE-HFDMG--LSPESEPESE--- 184

  Fly   259 KRGRPKTKKLVTADDNDDTSEVPVKRSSIKEMDDYIAANVKLDCAICAAPLEDFNDLKRHFRVEH 323
                        |.||.|||.                   ...|:.|....|:.::||.|....|
  Fly   185 ------------AIDNRDTSS-------------------SHTCSKCGLEFENVDELKLHKYHLH 218

  Fly   324 DC---TGYVKC--CNNRYKKRTLYVDHLHCHKDPQYFSCQSCRKNFLNRNSQVMH-MLRFHSQQ- 381
            |.   |.:| |  |:..::.......|.:....|...||..|:..|.|      | :|..|.|:
  Fly   219 DIPPDTKFV-CDHCDEGFRSAAALTRHCNMINLPLTHSCTKCKSQFHN------HILLETHKQRC 276

  Fly   382 ---QELVHQCAICEARFAKKFLLTMHLKGHKGTERPEVCDTCSKTFRTKFELSAHVKRMHAADFT 443
               ....|.|.||.......|.|..||..|.||.|.: ||.||.:|.|..||.:| ::.|..: .
  Fly   277 LRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHK-CDQCSASFYTAAELCSH-QKTHTTE-R 338

  Fly   444 PIICDI-CGTHFRSKANFLIHKKALHPDGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDGDTKY 507
            |.||.. ||..||..:...:|:: :|.|.                    .|.:           |
  Fly   339 PYICRYNCGKTFRFCSARSMHER-VHMDA--------------------SKRI-----------Y 371

  Fly   508 RCLLCNAEKSSRAALSSHMRYHHSAKRHKCSLCDKEFKLPRALAEHMATHTGIDLYQCQFCTRTF 572
            :|..|.....:.:...:|.:||:..:.|.|.:|...||    .|:|                  :
  Fly   372 QCEYCPKSYVTPSECRTHQKYHNLTRDHGCEICRISFK----TAKH------------------Y 414

  Fly   573 KSHANMHNHKKKMHPNDWVRKYSQPSSSITSTAAPLAHPN 612
            :||...:.||                 ::.:.|...|.||
  Fly   415 RSHLKSNAHK-----------------TLEARAKAAASPN 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071	19/77 (25%)
		C2H2 Zn finger	332..349	CDD:275368	2/16 (13%)
		C2H2 Zn finger	357..378	CDD:275368	6/21 (29%)
		C2H2 Zn finger	388..408	CDD:275368	7/19 (37%)
		C2H2 Zn finger	417..438	CDD:275368	9/20 (45%)
		C2H2 Zn finger	447..465	CDD:275368	6/18 (33%)
		C2H2 Zn finger	478..498	CDD:275368	1/19 (5%)
		C2H2 Zn finger	509..529	CDD:275368	3/19 (16%)
		C2H2 Zn finger	537..557	CDD:275368	6/19 (32%)
		C2H2 Zn finger	565..583	CDD:275368	3/17 (18%)
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	20/80 (25%)
		C2H2 Zn finger	228..254	CDD:275368	4/25 (16%)
		C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)
		C2H2 Zn finger	314..334	CDD:275368	9/20 (45%)
		C2H2 Zn finger	342..363	CDD:275368	6/21 (29%)
		C2H2 Zn finger	373..393	CDD:275368	3/19 (16%)
		C2H2 Zn finger	401..419	CDD:275368	8/39 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100