DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11696 and Kr

DIOPT Version :9

Sequence 1:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	NP_001261181.1	Gene:	Kr / 38012	FlyBaseID:	FBgn0001325	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	387	Identity:	82/387 - (21%)
Similarity:	136/387 - (35%)	Gaps:	90/387 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 TPDADEQPKPRGKRGRP-------KTKKLVTADDNDDTSEVPV----KRSSIKEMDDYIAANVKL 300
            :|::..|.....|:.|.       :|:..::.:|...||..|:    ..||.....|....|
  Fly   145 SPNSTPQHHEPAKKARKLSVKKEFQTEISMSVNDMYHTSGGPISPPSSGSSPNSTHDGAGGN--- 206

  Fly   301 DCAICAAPLEDFNDLKRHFRVEHDCTGYVKCCNNRYKKRTLYVDHLHCHKDPQYFSCQSCRKNFL 365
              |.|....:|         ...|.:...|.|:..:..:.:..:|...|...:.|.|..|.|.|.
  Fly   207 --AGCVGVSKD---------PSRDKSFTCKICSRSFGYKHVLQNHERTHTGEKPFECPECHKRFT 260

  Fly   366 NRNSQVMHMLRFHSQQQELVHQCAICEARFAKKFLLTMHLKGHKGTERPEVCDTCSKTFRTKFEL 430
            ..:....|| |.|:.::.  :.|:.|:.:|.:...|..||:.|.| |||..|:.|...|....:|
  Fly   261 RDHHLKTHM-RLHTGEKP--YHCSHCDRQFVQVANLRRHLRVHTG-ERPYTCEICDGKFSDSNQL 321

  Fly   431 SAHVKRMHAADFTPIICDICGTHFRSKANFLIHK--------KALHP----DGPVA------EVQ 477
            .:|: .:|..: .|..|:.|...||.:.:.:.||        .||.|    |.|||      |..
  Fly   322 KSHM-LVHNGE-KPFECERCHMKFRRRHHLMNHKCGIQSPPTPALSPAMSGDYPVAISAIAIEAS 384

  Fly   478 ----CTLCGRWLRDERSLRKHLARHDDRDGDTKYRCLLCNAEKSSRAALSSHMRYHHSAKRHKCS 538
                ..:|..:.....|:....|..:| ||.       .:..:...:::..|.   .:..|.|..
  Fly   385 TNRFAAMCATYGGSNESVDMEKATPED-DGP-------LDLSEDGASSVDGHC---SNIARRKAQ 438

  Fly   539 LCDKEFKL-------------------------PRALAEHMATHTGIDLYQCQFCTRTFKSH 575
            ...:.|:|                         ||::..|..| ..||||.......::..|
  Fly   439 DIRRVFRLPPPQIPHVPSDMPEQTEPEDLSMHSPRSIGSHEQT-DDIDLYDLDDAPASYMGH 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	332..349	CDD:275368	2/16 (13%)
		C2H2 Zn finger	357..378	CDD:275368	7/20 (35%)
		C2H2 Zn finger	388..408	CDD:275368	6/19 (32%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	447..465	CDD:275368	6/25 (24%)
		C2H2 Zn finger	478..498	CDD:275368	3/19 (16%)
		C2H2 Zn finger	509..529	CDD:275368	1/19 (5%)
		C2H2 Zn finger	537..557	CDD:275368	5/44 (11%)
		C2H2 Zn finger	565..583	CDD:275368	1/11 (9%)
Kr	NP_001261181.1	C2H2 Zn finger	224..244	CDD:275368	3/19 (16%)
		zf-H2C2_2	237..261	CDD:290200	7/23 (30%)
		C2H2 Zn finger	252..272	CDD:275368	7/20 (35%)
		zf-H2C2_2	264..289	CDD:290200	7/27 (26%)
		C2H2 Zn finger	280..300	CDD:275368	6/19 (32%)
		zf-H2C2_2	292..316	CDD:290200	10/24 (42%)
		C2H2 Zn finger	308..328	CDD:275368	5/20 (25%)
		zf-H2C2_2	321..345	CDD:290200	7/25 (28%)
		C2H2 Zn finger	336..352	CDD:275368	4/15 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100