Protein Alignment CG11696 and ZNF710

DIOPT Version :10

• Sequence 1: NP_572731.1
• Gene: CG11696 / 32104
• FlyBaseID: FBgn0030314
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: XP_047288438.1
• Gene: ZNF710 / 374655
• HGNCID: 25352
• Length: 702
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 143/628 - (22%)
• Similarity: 217/628 - (34%)
• Gaps: 188/628 - (29%)

  Fly   146 DTFEPDFEPE---SQPDEEEEPEPDPVKPRPRGRPRKTALQQ--THQIIK-----RKYEKRKQQN 200
            :.|.||..||   :...|.|.|.||..:....||    ||::  ..::::     .|:.:||.:.
Human    64 EAFYPDLGPELSGAAMGEPEPPGPDVYQLACNGR----ALEEPAEEEVLEVEAACEKHTRRKTRP 124

  Fly   201 KAK-ITELSLRESRARQRELKRSSAGAEDDQDGDEDEEDEEDVGGELTPDADEQP---------- 254
            ..: :.::...:....::|:...|...:|...|..:...|...||   .||..|.
Human   125 PVRLVPKVKFEKVEEEEQEVYEVSVPGDDKDAGPAEAPAEAASGG---CDALVQSSAVKMIDLSA 186

  Fly   255 ---KPRGKRGRPKTKKLVTADDNDDTSEVPVKRSSIKEMDDYIAANVK----------------- 299
               |||..|..|:|               |....::...|.:..|..:
Human   187 FSRKPRTLRHLPRT---------------PRPELNVAPYDPHFPAPARDGFPEPSMALPGPEALP 236

  Fly   300 LDCAI---CAAPLED-------------------FNDLKRHFRVEHDCTGYVKCCNNRYKKRTLY 342
            .:|..   ..|||.|                   :.:..   ..|.|..|...   .|:||..|.
Human   237 TECGFEPPHLAPLSDPEAPSMESPEPVKPEQGFVWQEAS---EFEADTAGSTV---ERHKKAQLD 295

  Fly   343 VDHLHCHKDPQY----------FSCQSCRKNFLNRNSQVMHMLRFHSQQQELVHQCAICEARFAK 397
            ...::...|..|          :.|:.|.|::.::.:.|.|:|..:..:.   |.|..|...|.:
Human   296 RLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKP---HSCPHCSKLFKQ 357

  Fly   398 KFLLTMHLKGHKGTERPEVCDTCSKTFRTKFELSAHVKR---MHAADFTPIICDICGTHFRSKAN 459
            ...|..||..|:|| ||..|..|.|.|..    ::|:||   :| ::..|..|..||..|...:.
Human   358 PSHLQTHLLTHQGT-RPHKCQVCHKAFTQ----TSHLKRHMLLH-SEVKPYSCHFCGRGFAYPSE 416

  Fly   460 FLIHKKALHPDGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDGDTKYRCLLCNAEKSSRAALSS 524
            ...| :..|..|...  .|..||........|::|||.|   .|.|.|:||.|:.....|:.|.:
Human   417 LKAH-EVKHESGRCH--VCVECGLDFSTLTQLKRHLASH---QGPTLYQCLECDKSFHYRSQLQN 475

  Fly   525 HMRYH------------------HSAKRH----------KCSLCDKEFKLPRALAEHMATHTGID 561
            ||..|                  |..|:|          ||.:|.:||.|...:..||..||.:.
Human   476 HMLKHQNVRPFVCTECGMEFSQIHHLKQHSLTHKGVKEFKCEVCGREFTLQANMKRHMLIHTSVR 540

  Fly   562 LYQCQFCTRTF------KSHANMHN----HKKKMHPNDWVRKYSQPSSSITSTAAPLAHPNHPNQ 616
            .|||..|.:||      |:|..:|:    .|.|:....:.|.|:.           |.| .|.:.
Human   541 PYQCHICFKTFVQKQTLKTHMIVHSPVKPFKCKVCGKSFNRMYNL-----------LGH-MHLHA 593

  Fly   617 PAPPAAAP---------TNLAGHM----------LPPLGGIAK 640
            .:.|...|         .||:.||          |...||.||
Human   594 GSKPFKCPYCSSKFNLKGNLSRHMKVKHGVMDIGLDSQGGWAK 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11696	NP_572731.1	zf-AD	2..81	CDD:462262
		C2H2 Zn finger	332..349	CDD:275368	4/16 (25%)
		C2H2 Zn finger	357..378	CDD:275368	6/20 (30%)
		C2H2 Zn finger	388..408	CDD:275368	6/19 (32%)
		C2H2 Zn finger	417..438	CDD:275368	7/23 (30%)
		C2H2 Zn finger	447..465	CDD:275368	5/17 (29%)
		C2H2 Zn finger	478..498	CDD:275368	7/19 (37%)
		C2H2 Zn finger	509..529	CDD:275368	7/19 (37%)
		zf-H2C2_2	521..545	CDD:463886	11/51 (22%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	565..583	CDD:275368	7/27 (26%)
ZNF710	XP_047288438.1	C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)
		C2H2 Zn finger	348..368	CDD:275368	6/19 (32%)
		COG5048	<358..616	CDD:227381	76/281 (27%)
		C2H2 Zn finger	376..396	CDD:275368	7/23 (30%)
		C2H2 Zn finger	404..424	CDD:275368	5/20 (25%)
		C2H2 Zn finger	432..452	CDD:275368	7/19 (37%)
		C2H2 Zn finger	460..480	CDD:275368	7/19 (37%)
		C2H2 Zn finger	488..508	CDD:275368	3/19 (16%)
		C2H2 Zn finger	516..536	CDD:275368	7/19 (37%)
		C2H2 Zn finger	544..564	CDD:275368	6/19 (32%)
		C2H2 Zn finger	572..592	CDD:275368	6/31 (19%)
		C2H2 Zn finger	600..619	CDD:275368	5/18 (28%)