DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11696 and Zfp212

DIOPT Version :9

Sequence 1:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_006236507.1	Gene:	Zfp212 / 297066	RGDID:	1307836	Length:	492	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	80/382 - (20%)
Similarity:	118/382 - (30%)	Gaps:	120/382 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 EDEEDVGGELTPDADEQPKPRGKRGRPKTKKLVTADDNDDTSEVPVKRSSIKE------MDDYIA 295
            |:|.::|.|:..|..|:......|...|.:.|.   ..:..|.:|...||..|      .:..:.
  Rat   187 EEEVELGAEMVGDLVEEGTHLADRAMVKQEMLY---KQEGPSGLPSMFSSAAEPQACFGSEQAVF 248

  Fly   296 ANVKLDCAICAAPLEDFNDLKRHFRVEHDCTGYVKCCNNRYKKRTLYVDHLHCHKDPQYFSCQSC 360
            .|...|.|:..:...|.|                                      |:  |.:|.
  Rat   249 WNSPGDSALLESGPGDSN--------------------------------------PE--SVESS 273

  Fly   361 RKNFLNRNSQVMHMLRFHSQQQ--------------ELVHQCAICEARFAKKFLLTMHLKGHKGT 411
            |.....||.......:.|.|.|              ...::|:.|:..|..|..||.||:.|...
  Rat   274 RDPAPGRNLDCPRKQKSHRQVQLGQECGQGPKVKRDTSPYKCSECQISFRYKQQLTAHLQSHTSR 338

  Fly   412 E-----RPEVCDTCSKTFRTKFELSAHVKR--MHAADFTPIICDICGTHFRSKANFLIHKKALHP 469
            |     .||      ::.|.:..|....||  :|.       ||:|...|..|.:.:.|::....
  Rat   339 ESYSATEPE------ESLRPRPRLKPQAKRSKLHQ-------CDVCHRSFSCKVSLVTHQRCHQQ 390

  Fly   470 DGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDGDTKYRCLLCNAEKSSRAALSSHMRYHHSAKR 534
            :||....|.        .||                        ...:|..||..|:.:..|...
  Rat   391 EGPSTSPQI--------QER------------------------FSPNSLVALPGHIPWRKSRSS 423

  Fly   535 HKCSLCDKEFKLPRALAEHMATHTGIDLYQCQFCTRTF--KSHANMHNHKKKMHPND 589
            ..|..|.|.|..|..|..|...|||...|.|..|.::|  |.|...|   :|:|..:
  Rat   424 LICGYCGKSFSHPSDLVRHQRIHTGERPYSCPECEKSFVQKQHLLQH---QKIHQRE 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	332..349	CDD:275368	0/16 (0%)
		C2H2 Zn finger	357..378	CDD:275368	4/20 (20%)
		C2H2 Zn finger	388..408	CDD:275368	8/19 (42%)
		C2H2 Zn finger	417..438	CDD:275368	4/22 (18%)
		C2H2 Zn finger	447..465	CDD:275368	6/17 (35%)
		C2H2 Zn finger	478..498	CDD:275368	2/19 (11%)
		C2H2 Zn finger	509..529	CDD:275368	4/19 (21%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	565..583	CDD:275368	6/19 (32%)
Zfp212	XP_006236507.1	KRAB_A-box	142..180	CDD:143639
		zf-C2H2	313..335	CDD:278523	8/21 (38%)
		C2H2 Zn finger	315..335	CDD:275368	8/19 (42%)
		COG5048	<329..>474	CDD:227381	46/192 (24%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		C2H2 Zn finger	426..446	CDD:275368	7/19 (37%)
		zf-C2H2	426..446	CDD:278523	7/19 (37%)
		zf-H2C2_2	438..463	CDD:290200	9/24 (38%)
		C2H2 Zn finger	454..474	CDD:275368	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350243
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030