DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11696 and si:dkeyp-69b9.6

DIOPT Version :9

Sequence 1:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_021322542.1	Gene:	si:dkeyp-69b9.6 / 100148274	ZFINID:	ZDB-GENE-100922-227	Length:	1462	Species:	Danio rerio

Alignment Length:	311	Identity:	77/311 - (24%)
Similarity:	110/311 - (35%)	Gaps:	77/311 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 CAICEARFAKKFLLTMHLKGHKGTERPEVCDTCSKTFRTKFELSAHVKRMHAADFTPIICDICGT 452
            |::|...||::..|..|.:.|.| |:|..|..|.|.||..|.||.| ..:|:.: ....|.:||.
Zfish   882 CSVCGRGFARRETLRRHDRIHTG-EKPHHCSVCGKYFREAFHLSKH-HTVHSGE-KNYKCILCGK 943

  Fly   453 HFRSKANFLIHKKALHPDGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDGDTKYRCLLCNAEKS 517
            .|....:...|.| ||..|.:.||..|          ...::|..:....|         |..:.
Zfish   944 DFGYAQSLKRHGK-LHQKGELEEVPTT----------PGIENLNSYPSSGG---------NLIQG 988

  Fly   518 SRAALSSHMRYHHSAKRH-----------KCSLCDKEFKLPRAL-AEHMATHT--GIDLYQCQFC 568
            .:::.||...|....|.|           .|::|.|.|:....| |.|...|.  |..|:.|:.|
Zfish   989 GQSSTSSFYPYSQDVKPHASNTQPPPRLYTCAICWKSFRHHFHLTAHHQTVHEGGGEKLFSCEVC 1053

  Fly   569 TRTFKSHANMHNHKKKMHPNDWVRKYSQPSSSITSTAAPLAH-------------------PNHP 614
            .:.|....::..|:...|             .:|.|..|:|.                   .|..
Zfish  1054 GKAFAYSNSLTRHRLSQH-------------GLTRTGQPVAQRSTGEETNVGGAISESEAATNAL 1105

  Fly   615 NQPAPPAAAPTN----LAGHMLP--PLGGIAKSLIEIPDTEG-FDFGSNSS 658
            .|.|||:.....    |..|..|  |.||.: .|..|||... ....||:|
Zfish  1106 LQLAPPSGTHGEQHGVLHSHHAPPQPQGGYS-PLFYIPDANATHPSSSNAS 1155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	332..349	CDD:275368
		C2H2 Zn finger	357..378	CDD:275368
		C2H2 Zn finger	388..408	CDD:275368	6/19 (32%)
		C2H2 Zn finger	417..438	CDD:275368	9/20 (45%)
		C2H2 Zn finger	447..465	CDD:275368	5/17 (29%)
		C2H2 Zn finger	478..498	CDD:275368	2/19 (11%)
		C2H2 Zn finger	509..529	CDD:275368	3/19 (16%)
		C2H2 Zn finger	537..557	CDD:275368	7/20 (35%)
		C2H2 Zn finger	565..583	CDD:275368	4/17 (24%)
si:dkeyp-69b9.6	XP_021322542.1	zf-C2H2	500..522	CDD:306579
		C2H2 Zn finger	502..522	CDD:275368
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..618	CDD:275368
		C2H2 Zn finger	625..641	CDD:275368
		C2H2 Zn finger	882..902	CDD:275368	6/19 (32%)
		zf-H2C2_2	895..918	CDD:316026	9/23 (39%)
		C2H2 Zn finger	910..930	CDD:275368	9/20 (45%)
		C2H2 Zn finger	938..958	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1019..1040	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1050..1068	CDD:275368	4/17 (24%)
		PHA00733	<1342..1393	CDD:177301
		C2H2 Zn finger	1342..1363	CDD:275368
		C2H2 Zn finger	1377..1397	CDD:275368
		C2H2 Zn finger	1405..1424	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591919
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930