Protein Alignment Reepl1 and REEP4

DIOPT Version :10

• Sequence 1: NP_572730.1
• Gene: Reepl1 / 32103
• FlyBaseID: FBgn0030313
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_079508.2
• Gene: REEP4 / 80346
• HGNCID: 26176
• Length: 257
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 54/258 - (20%)
• Similarity: 105/258 - (40%)
• Gaps: 67/258 - (25%)

  Fly     1 MIYAIVIHILSLLVGCFYPAFASYKILKSQNCSVNDLRGWLIYWIAYGVYVAFDYFTAGLLAFIP 65
            |:..::..::.|:.|...||:||||.:|::|  :.:...|::|||.:.:::|.:..|...:::.|
Human     1 MVSWMICRLVVLVFGMLCPAYASYKAVKTKN--IREYVRWMMYWIVFALFMAAEIVTDIFISWFP 63

  Fly    66 LLSEFKVLLLFWMLPSVGGGSEVIYEEFLR-SFSCNE-------------SFDQVLG-------- 108
            ...|.|:..:.|:|.....|:.::|.:|:. |.|.:|             |::.||.
Human    64 FYYEIKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDAYIVQAKERSYETVLSFGKRGLNI 128

  Fly   109 -------RITLEWGELVWQQVCSVLSHLMVLADRYLLPSGHRPALQITPSIEDLVNDAIAKRQLE 166
                   ..|...|.|..:.....:..|..::|. ..|:.|.|..     :||         |:.
Human   129 AASAAVQAATKSQGALAGRLRSFSMQDLRSISDA-PAPAYHDPLY-----LED---------QVS 178

  Fly   167 EKRKQMG------NLSDTINEVLGENIDLNMDLLHGSESDLLVIKEPISKPKERPIPPPKPMR 223
            .:|..:|      ..|||.:|..               ||...:....::|:|:|:...:.:|
Human   179 HRRPPIGYRAGGLQDSDTEDECW---------------SDTEAVPRAPARPREKPLIRSQSLR 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reepl1	NP_572730.1	TB2_DP1_HVA22	19..97	CDD:460820	22/78 (28%)
REEP4	NP_079508.2	TB2_DP1_HVA22	19..94	CDD:460820	22/76 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..257		11/59 (19%)