Protein Alignment Reepl1 and REEP3

DIOPT Version :10

• Sequence 1: NP_572730.1
• Gene: Reepl1 / 32103
• FlyBaseID: FBgn0030313
• Length: 240
• Species: Drosophila melanogaster
• Sequence 2: NP_001001330.1
• Gene: REEP3 / 221035
• HGNCID: 23711
• Length: 255
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 51/236 - (21%)
• Similarity: 92/236 - (38%)
• Gaps: 59/236 - (25%)

  Fly     1 MIYAIVIHILSLLVGCFYPAFASYKILKSQNCSVNDLRGWLIYWIAYGVYVAFDYFTAGLLAFIP 65
            |:..::...:.|:.|..|||:.|||.:|::|  |.:...|::|||.:.:|...:......:|:.|
Human     1 MVSWMISRAVVLVFGMLYPAYYSYKAVKTKN--VKEYVRWMMYWIVFALYTVIETVADQTVAWFP 63

  Fly    66 LLSEFKVLLLFWMLPSVGGGSEVIYEEFLRSFSCNESFDQVLGRITLEWGELVWQQVCSVLSHLM 130
            |..|.|:..:.|:|.....|:.:||.:||.                            .:||...
Human    64 LYYELKIAFVIWLLSPYTKGASLIYRKFLH----------------------------PLLSSKE 100

  Fly   131 VLADRYLLPSGHRPALQITPSIEDLVN------DAIAKRQLEEKRKQMGNLSDTINEVLGENIDL 189
            ...|.|::.:..|       ..|.:||      :..|...:....|..|.:::.:...
Human   101 REIDDYIVQAKER-------GYETMVNFGRQGLNLAATAAVTAAVKSQGAITERLRSF------- 151

  Fly   190 NMDLLHGSESDLLVIK--EPISKPKERPIPPPKPMRQPSSS 228
                   |..||..|:  ||:.:...:|:|..|...:|:.|
Human   152 -------SMHDLTTIQGDEPVGQRPYQPLPEAKKKSKPAPS 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reepl1	NP_572730.1	TB2_DP1_HVA22	19..97	CDD:460820	25/77 (32%)
REEP3	NP_001001330.1	TB2_DP1_HVA22	19..95	CDD:460820	25/105 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..242		8/28 (29%)