DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpII215 and Ubxn7

DIOPT Version :9

Sequence 1:	NP_511124.1	Gene:	RpII215 / 32100	FlyBaseID:	FBgn0003277	Length:	1887	Species:	Drosophila melanogaster
Sequence 2:	NP_808301.3	Gene:	Ubxn7 / 224111	MGIID:	2146388	Length:	489	Species:	Mus musculus

Alignment Length:	463	Identity:	89/463 - (19%)
Similarity:	150/463 - (32%)	Gaps:	142/463 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 STFRMNLSCTSPYNADFDGDEMNLHVPQSMETRAEVENIHITPRQIITPQANKPVMGIVQ----- 531
            ||...::|...|:..    :|:...:||..|...|.|.:...|::      .:|...|..
Mouse    60 STSSASVSTVRPHTE----EEVRAPIPQKQEILVEPEPLFGAPKR------RRPARSIFDGFRDF 114

  Fly   532 --DTLTAVRKM-----------TKRDVFITREQVMNLLMFLPTWDAKMPQ--------------P 569
              :|:...:::           |..|:|.....:|:...|....:....|              .
Mouse   115 QTETIRQEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFA 179

  Fly   570 CILKPRPLWTGKQIFSLIIPGNVNMIRTHST-----HPDEEDE--------GPYKWISPGD---- 617
            |....|.:|:.:.:        .|:||.|..     |..||.:        |.:.::|..|
Mouse   180 CQCLNRDVWSNEAV--------KNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTG 236

  Fly   618 ------------------TKVMVEHGELIMGI------LCKKS---LGTSAGSLLHICF---LEL 652
                              |..:.|||:| .|:      .|.:|   :..|..|.|....   |:.
Mouse   237 QKLVEWHQLDVSSFLDQVTGFLGEHGQL-DGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQE 300

  Fly   653 GH-DIAGRFYGNIQTVINNWLLFEGHSIGIGDTIADPQTYNEIQQAIKKAKDDVINVIQKAHNME 716
            .| |.|.....:.....:...||.|....|....:|.:  .|::...|..|....::   .|..|
Mouse   301 THFDSAQAKQDSRSDEESESELFSGSEEFISVCGSDEE--EEVENLAKSRKSPHKDL---GHRKE 360

  Fly   717 ------LEP----TPGN-TLRQTFENKVNRILNDARDKTGGSAKKSLTEYNNLKAMVV---SGSK 767
                  .||    .||. |..|...:..:.:|..:.:|:.|..:.  .:.|..||.::   ...|
Mouse   361 ENRRPLTEPPARTEPGTATNHQGLPSMDSEVLEMSPEKSDGIVEG--IDVNGPKAQLMLRYPDGK 423

  Fly   768 GSNINI---SQVIACVGQQNVEGKRIP-------YGFRKRTLPHFIKDDYGPESRGFVENSYLAG 822
            ...|.:   ::::|.|  ::|:.|..|       ..|.:|.|.|...|....|          ||
Mouse   424 REQITLPEQAKLLALV--KHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQE----------AG 476

  Fly   823 LTPSEFYF 830
            |.|.|..|
Mouse   477 LCPQETVF 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpII215	NP_511124.1	PRK08566	14..887	CDD:236292	89/463 (19%)
		RNAP_II_RPB1_N	15..868	CDD:259848	89/463 (19%)
		RNA_pol_Rpb1_5	822..1420	CDD:282807	5/9 (56%)
		RNA_pol_Rpb1_6	890..1071	CDD:282801
		RNAP_II_Rpb1_C	1050..1468	CDD:132720
		TCRP1	1602..1880	CDD:291605
		RCR	<1789..1864	CDD:304939
Ubxn7	NP_808301.3	UBA_UBXD7	16..51	CDD:270530
		UAS	149..261	CDD:239256	17/119 (14%)
		Faf1_like1_UBX	408..489	CDD:176368	22/89 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900