DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1572 and MYADM

DIOPT Version :9

Sequence 1:	NP_001285126.1	Gene:	CG1572 / 32098	FlyBaseID:	FBgn0030309	Length:	160	Species:	Drosophila melanogaster
Sequence 2:	NP_001018654.1	Gene:	MYADM / 91663	HGNCID:	7544	Length:	322	Species:	Homo sapiens

Alignment Length:	165	Identity:	35/165 - (21%)
Similarity:	63/165 - (38%)	Gaps:	45/165 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 TGYLKTFPGILKLFELIIGASIVGILAFNYQDYHRYFYGQQDLFHYLMAVTFMIGTF--CLLLAC 86
            |||:.|.||:||:.|..:...|..            |....:|:.:..|:.:.:..:  |.:||.
Human   166 TGYMATVPGLLKVLETFVACIIFA------------FISDPNLYQHQPALEWCVAVYAICFILAA 218

  Fly    87 LTSLSTGGIIAKTI---YELIYHSVAAILILVSSTILLL---------------KLRDV----KH 129
            :..|...|.....:   :......:|.:.:|:.:|.|:|               :.|||    .|
Human   219 IAILLNLGECTNVLPIPFPSFLSGLALLSVLLYATALVLWPLYQFDEKYGGQPRRSRDVSCSRSH 283

  Fly   130 -------DAYMAAGVLGLVNAVLYFISAFLAHRSY 157
                   |..:|..:|..:|.:.|.  |.|.|.::
Human   284 AYYVCAWDRRLAVAILTAINLLAYV--ADLVHSAH 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1572	NP_001285126.1	MARVEL	26..152	CDD:279608	31/156 (20%)
MYADM	NP_001018654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		MARVEL	45..152	CDD:366555
		MARVEL	168..312	CDD:366555	31/157 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4788
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900