Protein Alignment Drak and DCLK1

DIOPT Version :9

• Sequence 1: NP_001162723.1
• Gene: Drak / 32097
• FlyBaseID: FBgn0052666
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001317000.1
• Gene: DCLK1 / 9201
• HGNCID: 2700
• Length: 740
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 119/454 - (26%)
• Similarity: 197/454 - (43%)
• Gaps: 106/454 - (23%)

  Fly    32 INEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCEGEDN 96
            |.|.|:|.:| ...|.||.|:..:.::|...:|.|.:| :.:.:..:..|::|:::|...: ..|
Human   386 ITERYKVGRT-IGDGNFAVVKECVERSTAREYALKIIK-KSKCRGKEHMIQNEVSILRRVK-HPN 447

  Fly    97 IVNLNAVHETRSDTALLLELATGGELQTILDNEECLTEAQARHCMREVLKALKFLHDRSIAHLDL 161
            ||.|....:..::..|::||..||:|...:.:....||..|...:..:..|:|:||..:|.|.|:
Human   448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512

  Fly   162 KPQNILLAGERIEDG---LKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSV 223
            ||:|:|:...  :||   |||.|||::.:| :| .:..:.|||.|||||::......|..|||:.
Human   513 KPENLLVYEH--QDGSKSLKLGDFGLATIV-DG-PLYTVCGTPTYVAPEIIAETGYGLKVDIWAA 573

  Fly   224 GVLTYVLLSGFSPF--GGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNA 286
            ||:||:||.||.||  .||.::..|..|....:.||...:..||..|.:.|...|.:..:.|.:|
Human   574 GVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSA 638

  Fly   287 TGCLDHIWLKDDCSLDRQIYLQPQSDAEEEEEEDVDDDVEDEEEEEQVEEEEEETQNVEEPTTEA 351
            ...|:|.|:.||
Human   639 VQVLEHPWVNDD----------------------------------------------------- 650

  Fly   352 PQQQQQPVQQHQLAKSGQIHSKPTHNGHHRANSGGSISKIPIATSKLQSTPSSETTTAIHTLTSN 416
                ..|..:|||:.:|:| .|..:.|....::...:|.|              .|||:
Human   651 ----GLPENEHQLSVAGKI-KKHFNTGPKPNSTAAGVSVI--------------ATTAL------ 690

  Fly   417 SNGHVHKPTQIVTPTRRASDSDKENTYTATFVKKPVATIQLGSSNGIEDATVVATLTL-FPDAP 479
                 .|..|:.   ||..:.|..:.|.|    :| |..:|.|.:  ||.:..::.|: .|::|
Human   691 -----DKERQVF---RRRRNQDVRSRYKA----QP-APPELNSES--EDYSPSSSETVRSPNSP 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	87/267 (33%)
		S_TKc	45..295	CDD:214567	82/254 (32%)
		PHA03255	379..>554	CDD:165513	21/102 (21%)
DCLK1	NP_001317000.1	DCX1_DCLK1	55..143	CDD:340660
		DCX2	182..265	CDD:340589
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..378
		STKc_DCKL1	383..650	CDD:271085	88/270 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	697..740		14/53 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910