Protein Alignment Drak and mark2

DIOPT Version :9

• Sequence 1: NP_001162723.1
• Gene: Drak / 32097
• FlyBaseID: FBgn0052666
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_012808991.1
• Gene: mark2 / 594939
• XenbaseID: XB-GENE-876451
• Length: 792
• Species: Xenopus tropicalis
• Alignment Length: 636
• Identity: 162/636 - (25%)
• Similarity: 270/636 - (42%)
• Gaps: 135/636 - (21%)

  Fly    36 YEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCEGEDNIVNL 100
            |.:.:| ..:|.||.|:.|.|..||...|.|.:.:.:...||.:::..|:.::.:. ...|||.|
 Frog    64 YRLLKT-IGKGNFAKVKLARHVLTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL-NHPNIVKL 126

  Fly   101 NAVHETRSDTALLLELATGGELQTILDNEECLTEAQARHCMREVLKALKFLHDRSIAHLDLKPQN 165
            ..|.||.....|::|.|:|||:...|.....:.|.:||...|:::.|:::.|.:.|.|.|||.:|
 Frog   127 FEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKLIVHRDLKAEN 191

  Fly   166 ILLAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQ---YEPLSLLTDIWSVGVLT 227
            :||..:.   .:|:.|||.|.....|..:....|:|.|.|||:.|   |:...:  |:||:||:.
 Frog   192 LLLDSDM---NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEV--DVWSLGVIL 251

  Fly   228 YVLLSGFSPFGGDTKQETFLNISQCALTFP-------DNLFGGVSPVAIDFIRRALRIKPNDRMN 285
            |.|:||..||.|...:|....:.:.....|       :||           :::.|.:.|..|
 Frog   252 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENL-----------LKKFLILNPAKR-- 303

  Fly   286 ATGCLDHI----WL----KDDCSLDRQIYLQPQSDAEEEE-----------EEDVDDDVEDEEEE 331
              |.|:.|    |:    ::|   :.:.|::|..|.::.:           .|::.|.:.:::..
 Frog   304 --GTLEQIMRDRWMNVGHEED---ELKPYVEPIPDYKDPKRTELMITMGYTREEISDSLVNQKYN 363

  Fly   332 EQVEE------EEEETQNVEEPTTEAPQQQQQPVQQHQLAKSGQIHSKPTHNGHHRANSGGSISK 390
            |.:..      :..||.|  :..|..|  :..|...:.:|.|      |.|....      |:|.
 Frog   364 EVMATYLLLGYKSSETDN--DNLTLKP--RPPPDVTNSIAPS------PAHKVQR------SVSA 412

  Fly   391 IPIATSKLQSTPSSETTTAIHTLTSNSNGHVHKPTQIVTPTRRASDSDKENTYTATFVKKPVATI 455
            .|     .|...|.:...||    .|||.: .|.||......|.|:.|||:.      :|..:|:
 Frog   413 NP-----KQRRLSDQAGPAI----PNSNSY-SKKTQSNNAENRRSEDDKESG------RKSSSTV 461

  Fly   456 QLGSS--NGIEDATVVATLTLFPDAPTTPKVIRKTPTGESNGSATSVKALVKKFQLEDSSGSAVA 518
            ::..|  :|::......|       |:|..|: .|.|..|..|....:|            |.|.
 Frog   462 RVPPSPLSGLDRKKTTPT-------PSTNSVL-STGTNRSRNSPMLDRA------------SLVP 506

  Fly   519 RRSGGAVTSSSGLHSPTTTSVRLNSIRRASEPLTTVYKKQTSQNGCSSTSNPSSSPGSSPTTSGS 583
                |:|  .:|..|.:|...|.::   ||.|.|:...:| .|...|::.:||.   .:|:..|:
 Frog   507 ----GSV--QNGKDSFSTPGSRAST---ASAPATSARIRQ-HQKSMSTSVHPSK---PAPSLDGN 558

  Fly   584 TATLLIHSQRLGNSTAPASHCVAVPATATATSSASS-SNSSSGKSTSAAHH 633
            ...     ||  .||||....||.|:....:|:|:. :|...|.|:.:..|
 Frog   559 CEV-----QR--PSTAPQRVPVASPSAHNISSAATERTNFPRGVSSRSTFH 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	79/272 (29%)
		S_TKc	45..295	CDD:214567	77/263 (29%)
		PHA03255	379..>554	CDD:165513	43/176 (24%)
mark2	XP_012808991.1	STKc_MARK	63..315	CDD:270974	79/272 (29%)
		UBA_MARK2	333..374	CDD:270589	4/40 (10%)
		MARK2_C	693..791	CDD:213386

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000